SG11201803043VA - Derivation of human skin organoids from pluripotent stem cells - Google Patents

Derivation of human skin organoids from pluripotent stem cells

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Publication number
SG11201803043VA
SG11201803043VA SG11201803043VA SG11201803043VA SG11201803043VA SG 11201803043V A SG11201803043V A SG 11201803043VA SG 11201803043V A SG11201803043V A SG 11201803043VA SG 11201803043V A SG11201803043V A SG 11201803043VA SG 11201803043V A SG11201803043V A SG 11201803043VA
Authority
SG
Singapore
Prior art keywords
derivation
stem cells
pluripotent stem
human skin
skin organoids
Prior art date
Application number
SG11201803043VA
Inventor
Karl Koehler
Jiyoon Lee
Original Assignee
Univ Indiana Res & Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Indiana Res & Tech Corp filed Critical Univ Indiana Res & Tech Corp
Publication of SG11201803043VA publication Critical patent/SG11201803043VA/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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