SI3818078T1 - Postopki za proizvodnjo rekombinantnih proteinov - Google Patents

Postopki za proizvodnjo rekombinantnih proteinov

Info

Publication number
SI3818078T1
SI3818078T1 SI201930722T SI201930722T SI3818078T1 SI 3818078 T1 SI3818078 T1 SI 3818078T1 SI 201930722 T SI201930722 T SI 201930722T SI 201930722 T SI201930722 T SI 201930722T SI 3818078 T1 SI3818078 T1 SI 3818078T1
Authority
SI
Slovenia
Prior art keywords
methods
recombinant proteins
producing recombinant
producing
proteins
Prior art date
Application number
SI201930722T
Other languages
English (en)
Inventor
Jianlin Xu
Andrew Yongky
Jun Tian
Michael C. BORYS
Zhengjian Li
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of SI3818078T1 publication Critical patent/SI3818078T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SI201930722T 2018-07-03 2019-07-02 Postopki za proizvodnjo rekombinantnih proteinov SI3818078T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862693606P 2018-07-03 2018-07-03
EP19745845.8A EP3818078B1 (en) 2018-07-03 2019-07-02 Methods of producing recombinant proteins
PCT/US2019/040298 WO2020010080A1 (en) 2018-07-03 2019-07-02 Methods of producing recombinant proteins

Publications (1)

Publication Number Publication Date
SI3818078T1 true SI3818078T1 (sl) 2024-05-31

Family

ID=67470657

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201930722T SI3818078T1 (sl) 2018-07-03 2019-07-02 Postopki za proizvodnjo rekombinantnih proteinov

Country Status (23)

Country Link
US (1) US20210253996A1 (sl)
EP (2) EP3818078B1 (sl)
JP (2) JP7419273B2 (sl)
KR (1) KR20210027427A (sl)
CN (1) CN112839954A (sl)
AU (1) AU2019299358A1 (sl)
BR (1) BR112020025623A2 (sl)
CA (1) CA3104684A1 (sl)
DK (1) DK3818078T3 (sl)
EA (1) EA202092904A1 (sl)
ES (1) ES2976708T3 (sl)
FI (1) FI3818078T3 (sl)
HR (1) HRP20240584T1 (sl)
HU (1) HUE066560T2 (sl)
IL (1) IL279782A (sl)
LT (1) LT3818078T (sl)
MX (1) MX2020013633A (sl)
PL (1) PL3818078T3 (sl)
PT (1) PT3818078T (sl)
RS (1) RS65472B1 (sl)
SG (1) SG11202012582QA (sl)
SI (1) SI3818078T1 (sl)
WO (1) WO2020010080A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023242238A1 (en) * 2022-06-15 2023-12-21 UCB Biopharma SRL Cell culture processes
EP4339274A1 (en) 2022-09-13 2024-03-20 Sartorius Stedim Biotech GmbH Method for operating a bioprocess installation for production of a bioproduct

Family Cites Families (28)

* Cited by examiner, † Cited by third party
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US5672347A (en) 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
EP0420937B1 (en) 1988-06-21 1994-11-09 Genentech, Inc. Therapeutic compositions for the treatment of myocardial infarction
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
DE122006000006I2 (de) 1991-08-14 2011-06-16 Genentech Inc Veränderte Immunglobuline für spezifische FC-Epsilon Rezeptoren
ES2112431T3 (es) 1992-08-21 1998-04-01 Genentech Inc Procedimiento para el tratamiento de un trastorno mediado por lfa-1.
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
DE69405251T2 (de) 1993-12-10 1998-02-05 Genentech Inc Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika
DE69501817T2 (de) 1994-01-18 1998-09-10 Genentech Inc Verfahren zur behandlung von parasitären infektionen unter verwendung von ige-antagonisten
JP3780315B2 (ja) 1994-03-03 2006-05-31 ジェネンテク・インコーポレイテッド 炎症性疾患の処置のための抗il−8モノクローナル抗体
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
WO1996040210A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
WO1997026912A2 (en) 1996-01-23 1997-07-31 Genentech, Inc. Anti-cd18 antibodies for use against stroke
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
WO1998023761A1 (en) 1996-11-27 1998-06-04 Genentech, Inc. HUMANIZED ANTI-CD11a ANTIBODIES
DE122007000021I1 (de) 1997-04-07 2007-05-24 Genentech Inc Anti-vefg Antibodies
DE69838249T3 (de) 1997-05-15 2012-01-19 Genentech, Inc. Anti-apo-2 antikörper
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
NZ518477A (en) 1999-10-29 2004-10-29 Genentech Inc Isolated anti-prostate stem cell antigen (PSCA) antibodies that internalise upon binding to PSCA on a mammalian cell, including a PSCA-expressing tumour cell, in vivo
TWI374935B (en) * 2004-08-27 2012-10-21 Pfizer Ireland Pharmaceuticals Production of α-abeta
SG10201510384UA (en) * 2006-09-13 2016-01-28 Abbvie Inc Cell culture improvements
SI2767546T1 (sl) 2011-02-07 2019-03-29 Cerenis Therapeutics Holding Sa Lipoproteinski kompleksi in izdelava ter uporaba le-teh
CN103827292B (zh) * 2011-07-01 2018-01-26 安姆根有限公司 哺乳动物细胞培养
CN106536746A (zh) * 2014-06-03 2017-03-22 鲁宾有限公司 用于生产蛋白的细胞培养方法
WO2015198451A1 (ja) 2014-06-26 2015-12-30 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
PT3818078T (pt) 2024-04-18
JP2021529527A (ja) 2021-11-04
CN112839954A (zh) 2021-05-25
IL279782A (en) 2021-03-01
EA202092904A1 (ru) 2021-04-22
HRP20240584T1 (hr) 2024-07-19
FI3818078T3 (fi) 2024-05-14
DK3818078T3 (da) 2024-05-21
MX2020013633A (es) 2021-03-25
AU2019299358A1 (en) 2021-02-18
US20210253996A1 (en) 2021-08-19
LT3818078T (lt) 2024-04-25
HUE066560T2 (hu) 2024-08-28
EP3818078A1 (en) 2021-05-12
EP4368699A3 (en) 2024-09-11
SG11202012582QA (en) 2021-01-28
KR20210027427A (ko) 2021-03-10
EP4368699A2 (en) 2024-05-15
PL3818078T3 (pl) 2024-04-29
JP7419273B2 (ja) 2024-01-22
JP2024050590A (ja) 2024-04-10
RS65472B1 (sr) 2024-05-31
ES2976708T3 (es) 2024-08-07
CA3104684A1 (en) 2020-01-09
BR112020025623A2 (pt) 2021-03-23
EP3818078B1 (en) 2024-02-28
WO2020010080A1 (en) 2020-01-09

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