SI3309149T1 - Kristal 6-bromo-3-hidroksi-2-pirazinkarboksamida in metoda priprave le-tega - Google Patents
Kristal 6-bromo-3-hidroksi-2-pirazinkarboksamida in metoda priprave le-tegaInfo
- Publication number
- SI3309149T1 SI3309149T1 SI201631237T SI201631237T SI3309149T1 SI 3309149 T1 SI3309149 T1 SI 3309149T1 SI 201631237 T SI201631237 T SI 201631237T SI 201631237 T SI201631237 T SI 201631237T SI 3309149 T1 SI3309149 T1 SI 3309149T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pyrazinecarboxamide
- bromo
- hydroxy
- crystal
- producing same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562172958P | 2015-06-09 | 2015-06-09 | |
| EP16807530.7A EP3309149B1 (en) | 2015-06-09 | 2016-06-08 | 6-bromo-3-hydroxy-2-pyrazinecarboxamide crystal and method for producing same |
| PCT/JP2016/067114 WO2016199824A1 (ja) | 2015-06-09 | 2016-06-08 | ６－ブロモ－３－ヒドロキシ－２－ピラジンカルボキサミドの結晶およびその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3309149T1 true SI3309149T1 (sl) | 2021-09-30 |
Family
ID=57503297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201631237T SI3309149T1 (sl) | 2015-06-09 | 2016-06-08 | Kristal 6-bromo-3-hidroksi-2-pirazinkarboksamida in metoda priprave le-tega |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10266501B2 (sl) |
| EP (1) | EP3309149B1 (sl) |
| JP (1) | JP6705817B2 (sl) |
| CN (1) | CN107635976A (sl) |
| CY (1) | CY1124180T1 (sl) |
| DK (1) | DK3309149T3 (sl) |
| ES (1) | ES2865296T3 (sl) |
| HK (1) | HK1248236A1 (sl) |
| HR (1) | HRP20211070T1 (sl) |
| HU (1) | HUE054654T2 (sl) |
| LT (1) | LT3309149T (sl) |
| PL (1) | PL3309149T3 (sl) |
| PT (1) | PT3309149T (sl) |
| SI (1) | SI3309149T1 (sl) |
| WO (1) | WO2016199824A1 (sl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111349049B (zh) * | 2020-02-28 | 2022-11-11 | 江苏阿尔法药业股份有限公司 | 一种法匹拉韦及其中间体的合成工艺 |
| US11780817B2 (en) * | 2020-05-18 | 2023-10-10 | Weaver Labs, LLC | Methods for preparing Favipiravir |
| CN112851589B (zh) * | 2021-01-25 | 2022-10-11 | 山东邹平大展新材料有限公司 | 一种法匹拉韦中间体6-溴-3-羟基吡嗪-2-甲酰胺的制备方法 |
| CN113461622B (zh) * | 2021-08-11 | 2023-04-07 | 海正药业南通有限公司 | 一种法匹拉韦中间体6-溴-3-羟基吡嗪-2-甲酰胺的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0108374B8 (pt) | 2000-02-16 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivado de pirazina ou um sal deste e composição farmacêutica |
| JP5550347B2 (ja) | 2007-09-27 | 2014-07-16 | 富山化学工業株式会社 | ６−フルオロ−３−ヒドロキシ−２−ピラジンカルボニトリルの有機アミン塩およびその製造法 |
| EP2392566B1 (en) * | 2009-01-28 | 2016-03-02 | Nippon Soda Co., Ltd. | Method for producing dichloropyrazine derivative |
| JP5739618B2 (ja) * | 2009-03-18 | 2015-06-24 | 富山化学工業株式会社 | ３−ヒドロキシ−２−ピラジンカルボキサミドの製造法 |
| JP5559604B2 (ja) * | 2009-05-27 | 2014-07-23 | 富山化学工業株式会社 | ３，６−ジクロロ−２−ピラジンカルボニトリルの製造法 |
| CN102775358B (zh) * | 2012-08-22 | 2015-05-27 | 山东齐都药业有限公司 | 6-氟-3-羟基-2-吡嗪酰胺的制备方法 |
-
2016
- 2016-06-08 ES ES16807530T patent/ES2865296T3/es active Active
- 2016-06-08 DK DK16807530.7T patent/DK3309149T3/da active
- 2016-06-08 PL PL16807530T patent/PL3309149T3/pl unknown
- 2016-06-08 JP JP2017523678A patent/JP6705817B2/ja active Active
- 2016-06-08 US US15/580,731 patent/US10266501B2/en active Active
- 2016-06-08 CN CN201680033471.XA patent/CN107635976A/zh active Pending
- 2016-06-08 EP EP16807530.7A patent/EP3309149B1/en active Active
- 2016-06-08 PT PT168075307T patent/PT3309149T/pt unknown
- 2016-06-08 HU HUE16807530A patent/HUE054654T2/hu unknown
- 2016-06-08 SI SI201631237T patent/SI3309149T1/sl unknown
- 2016-06-08 WO PCT/JP2016/067114 patent/WO2016199824A1/ja active Application Filing
- 2016-06-08 LT LTEP16807530.7T patent/LT3309149T/lt unknown
-
2018
- 2018-06-15 HK HK18107817.6A patent/HK1248236A1/zh unknown
-
2019
- 2019-03-05 US US16/293,100 patent/US10519117B2/en active Active
-
2021
- 2021-05-26 CY CY20211100457T patent/CY1124180T1/el unknown
- 2021-07-06 HR HRP20211070TT patent/HRP20211070T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL3309149T3 (pl) | 2021-10-25 |
| LT3309149T (lt) | 2021-06-25 |
| US10519117B2 (en) | 2019-12-31 |
| EP3309149B1 (en) | 2021-04-07 |
| HRP20211070T1 (hr) | 2021-10-01 |
| PT3309149T (pt) | 2021-05-14 |
| CY1124180T1 (el) | 2022-05-27 |
| JPWO2016199824A1 (ja) | 2018-03-29 |
| EP3309149A1 (en) | 2018-04-18 |
| CN107635976A (zh) | 2018-01-26 |
| EP3309149A4 (en) | 2019-01-09 |
| JP6705817B2 (ja) | 2020-06-03 |
| ES2865296T3 (es) | 2021-10-15 |
| HUE054654T2 (hu) | 2021-09-28 |
| US20190194146A1 (en) | 2019-06-27 |
| US10266501B2 (en) | 2019-04-23 |
| DK3309149T3 (da) | 2021-05-31 |
| HK1248236A1 (zh) | 2018-10-12 |
| US20180141920A1 (en) | 2018-05-24 |
| WO2016199824A1 (ja) | 2016-12-15 |
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