PT3309149T - Cristal de 6-bromo-3-hidroxi-2-pirazinocarboxamida e processo para a sua produção - Google Patents
Cristal de 6-bromo-3-hidroxi-2-pirazinocarboxamida e processo para a sua produçãoInfo
- Publication number
- PT3309149T PT3309149T PT168075307T PT16807530T PT3309149T PT 3309149 T PT3309149 T PT 3309149T PT 168075307 T PT168075307 T PT 168075307T PT 16807530 T PT16807530 T PT 16807530T PT 3309149 T PT3309149 T PT 3309149T
- Authority
- PT
- Portugal
- Prior art keywords
- pyrazinecarboxamide
- bromo
- hydroxy
- crystal
- producing same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562172958P | 2015-06-09 | 2015-06-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3309149T true PT3309149T (pt) | 2021-05-14 |
Family
ID=57503297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT168075307T PT3309149T (pt) | 2015-06-09 | 2016-06-08 | Cristal de 6-bromo-3-hidroxi-2-pirazinocarboxamida e processo para a sua produção |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10266501B2 (pt) |
| EP (1) | EP3309149B1 (pt) |
| JP (1) | JP6705817B2 (pt) |
| CN (2) | CN120081794A (pt) |
| CY (1) | CY1124180T1 (pt) |
| DK (1) | DK3309149T3 (pt) |
| ES (1) | ES2865296T3 (pt) |
| HK (1) | HK1248236A1 (pt) |
| HR (1) | HRP20211070T1 (pt) |
| HU (1) | HUE054654T2 (pt) |
| LT (1) | LT3309149T (pt) |
| PL (1) | PL3309149T3 (pt) |
| PT (1) | PT3309149T (pt) |
| SI (1) | SI3309149T1 (pt) |
| WO (1) | WO2016199824A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111349049B (zh) * | 2020-02-28 | 2022-11-11 | 江苏阿尔法药业股份有限公司 | 一种法匹拉韦及其中间体的合成工艺 |
| US11780817B2 (en) * | 2020-05-18 | 2023-10-10 | Weaver Labs, LLC | Methods for preparing Favipiravir |
| CN114057656B (zh) * | 2020-08-05 | 2025-11-18 | 广东东阳光药业股份有限公司 | 一种法匹拉韦共晶及其制备方法 |
| CN112851589B (zh) * | 2021-01-25 | 2022-10-11 | 山东邹平大展新材料有限公司 | 一种法匹拉韦中间体6-溴-3-羟基吡嗪-2-甲酰胺的制备方法 |
| CN113461622B (zh) * | 2021-08-11 | 2023-04-07 | 海正药业南通有限公司 | 一种法匹拉韦中间体6-溴-3-羟基吡嗪-2-甲酰胺的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100589935B1 (ko) | 2000-02-16 | 2006-06-15 | 토야마 케미칼 컴퍼니 리미티드 | 신규한 피라진 유도체 또는 그 염, 및 이를 함유하는 의약 조성물 |
| KR101686813B1 (ko) | 2007-09-27 | 2016-12-16 | 토야마 케미칼 컴퍼니 리미티드 | 6-플루오로-3-히드록시-2-피라진카보니트릴의 유기아민염 및 그 제조법 |
| KR101297541B1 (ko) * | 2009-01-28 | 2013-08-14 | 닛뽕소다 가부시키가이샤 | 디클로로피라진 유도체의 제조 방법 |
| JP5739618B2 (ja) | 2009-03-18 | 2015-06-24 | 富山化学工業株式会社 | ３−ヒドロキシ−２−ピラジンカルボキサミドの製造法 |
| JP5559604B2 (ja) | 2009-05-27 | 2014-07-23 | 富山化学工業株式会社 | ３，６−ジクロロ−２−ピラジンカルボニトリルの製造法 |
| CN102775358B (zh) * | 2012-08-22 | 2015-05-27 | 山东齐都药业有限公司 | 6-氟-3-羟基-2-吡嗪酰胺的制备方法 |
-
2016
- 2016-06-08 CN CN202510238014.5A patent/CN120081794A/zh active Pending
- 2016-06-08 EP EP16807530.7A patent/EP3309149B1/en active Active
- 2016-06-08 SI SI201631237T patent/SI3309149T1/sl unknown
- 2016-06-08 PL PL16807530T patent/PL3309149T3/pl unknown
- 2016-06-08 DK DK16807530.7T patent/DK3309149T3/da active
- 2016-06-08 HU HUE16807530A patent/HUE054654T2/hu unknown
- 2016-06-08 HK HK18107817.6A patent/HK1248236A1/zh unknown
- 2016-06-08 US US15/580,731 patent/US10266501B2/en active Active
- 2016-06-08 ES ES16807530T patent/ES2865296T3/es active Active
- 2016-06-08 PT PT168075307T patent/PT3309149T/pt unknown
- 2016-06-08 WO PCT/JP2016/067114 patent/WO2016199824A1/ja not_active Ceased
- 2016-06-08 HR HRP20211070TT patent/HRP20211070T1/hr unknown
- 2016-06-08 JP JP2017523678A patent/JP6705817B2/ja active Active
- 2016-06-08 LT LTEP16807530.7T patent/LT3309149T/lt unknown
- 2016-06-08 CN CN201680033471.XA patent/CN107635976A/zh active Pending
-
2019
- 2019-03-05 US US16/293,100 patent/US10519117B2/en active Active
-
2021
- 2021-05-26 CY CY20211100457T patent/CY1124180T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1248236A1 (zh) | 2018-10-12 |
| CN107635976A (zh) | 2018-01-26 |
| EP3309149A1 (en) | 2018-04-18 |
| US20190194146A1 (en) | 2019-06-27 |
| HRP20211070T1 (hr) | 2021-10-01 |
| PL3309149T3 (pl) | 2021-10-25 |
| SI3309149T1 (sl) | 2021-09-30 |
| HUE054654T2 (hu) | 2021-09-28 |
| DK3309149T3 (da) | 2021-05-31 |
| JP6705817B2 (ja) | 2020-06-03 |
| WO2016199824A1 (ja) | 2016-12-15 |
| US10519117B2 (en) | 2019-12-31 |
| US10266501B2 (en) | 2019-04-23 |
| CN120081794A (zh) | 2025-06-03 |
| EP3309149A4 (en) | 2019-01-09 |
| JPWO2016199824A1 (ja) | 2018-03-29 |
| US20180141920A1 (en) | 2018-05-24 |
| CY1124180T1 (el) | 2022-05-27 |
| EP3309149B1 (en) | 2021-04-07 |
| ES2865296T3 (es) | 2021-10-15 |
| LT3309149T (lt) | 2021-06-25 |
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