SI3240538T1 - Uporaba masitiniba za zdravljenje subpopulacije bolnikov z amiotrofično lateralno sklerozo - Google Patents
Uporaba masitiniba za zdravljenje subpopulacije bolnikov z amiotrofično lateralno sklerozoInfo
- Publication number
- SI3240538T1 SI3240538T1 SI201730997T SI201730997T SI3240538T1 SI 3240538 T1 SI3240538 T1 SI 3240538T1 SI 201730997 T SI201730997 T SI 201730997T SI 201730997 T SI201730997 T SI 201730997T SI 3240538 T1 SI3240538 T1 SI 3240538T1
- Authority
- SI
- Slovenia
- Prior art keywords
- masitinib
- subpopulations
- patients
- treatment
- lateral sclerosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16162490 | 2016-03-25 | ||
| PCT/EP2017/057134 WO2017162884A1 (en) | 2016-03-25 | 2017-03-24 | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation |
| EP17712175.3A EP3240538B1 (en) | 2016-03-25 | 2017-03-24 | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3240538T1 true SI3240538T1 (sl) | 2022-02-28 |
Family
ID=55637258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201730997T SI3240538T1 (sl) | 2016-03-25 | 2017-03-24 | Uporaba masitiniba za zdravljenje subpopulacije bolnikov z amiotrofično lateralno sklerozo |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10092564B2 (OSRAM) |
| EP (1) | EP3240538B1 (OSRAM) |
| JP (2) | JP7250312B2 (OSRAM) |
| KR (1) | KR102293847B1 (OSRAM) |
| CN (1) | CN108883108B (OSRAM) |
| AU (1) | AU2017236177B2 (OSRAM) |
| BR (1) | BR112018069515A2 (OSRAM) |
| CA (1) | CA3018635C (OSRAM) |
| DK (1) | DK3240538T3 (OSRAM) |
| EA (1) | EA038531B1 (OSRAM) |
| ES (1) | ES2899929T3 (OSRAM) |
| HU (1) | HUE057398T2 (OSRAM) |
| IL (1) | IL261856B (OSRAM) |
| MX (1) | MX390495B (OSRAM) |
| NZ (1) | NZ745778A (OSRAM) |
| PL (1) | PL3240538T3 (OSRAM) |
| PT (1) | PT3240538T (OSRAM) |
| SG (1) | SG11201808106YA (OSRAM) |
| SI (1) | SI3240538T1 (OSRAM) |
| WO (1) | WO2017162884A1 (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| CN109846862A (zh) | 2012-10-25 | 2019-06-07 | 通用医疗公司 | 治疗阿尔茨海默病及相关疾病的组合疗法 |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| EP3060205A4 (en) | 2013-10-22 | 2017-06-28 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| WO2018045217A1 (en) | 2016-08-31 | 2018-03-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| EP3425390B1 (en) | 2016-11-25 | 2020-12-23 | Genuv Inc. | Composition for promoting differentiation of and protecting neural stem cells and method for inducing neural regeneration using same |
| CN116139135A (zh) * | 2017-03-28 | 2023-05-23 | 诺华股份有限公司 | 治疗多发性硬化的方法 |
| JP6957650B2 (ja) * | 2017-05-30 | 2021-11-02 | デシフェラ・ファーマシューティカルズ，エルエルシー | 血小板由来成長因子受容体アルファの遺伝的異常に関連する癌の治療のための、１−［４−ブロモ−５−［１−エチル−７−（メチルアミノ）−２−オキソ−１，２−ジヒドロ−１，６−ナフチリジン−３−イル］−２−フルオロフェニル］−３−フェニルウレアおよびアナログの使用 |
| JP7463281B2 (ja) * | 2018-03-05 | 2024-04-08 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | コロニー刺激因子を標的とすることによる、緑内障および視神経症のための療法 |
| CN113038944A (zh) | 2018-07-02 | 2021-06-25 | 通用医疗公司 | 色甘酸钠和α-乳糖的粉末化制剂 |
| MX2021006869A (es) | 2018-12-10 | 2021-07-02 | Massachusetts Gen Hospital | Esteres de cromolin y usos de los mismos. |
| CN112618717A (zh) * | 2019-09-24 | 2021-04-09 | 北京大学深圳研究生院 | Btk抑制剂用于治疗肌萎缩侧索硬化症的用途 |
| KR20250057151A (ko) * | 2019-12-30 | 2025-04-28 | 데시페라 파마슈티칼스, 엘엘씨 | 1-(4-브로모-5-(1-에틸-7-(메틸아미노)-2-옥소-1,2-디히드로-1,6-나프티리딘-3-일)-2-플루오로페닐)-3-페닐우레아의조성물 |
| WO2021207060A1 (en) | 2020-04-06 | 2021-10-14 | The General Hospital Corporation | Methods of treatment of coronavirus-induced inflammation conditions |
| WO2025113494A1 (zh) * | 2023-11-27 | 2025-06-05 | 浙江径科医药有限公司 | 多环类化合物及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW225528B (OSRAM) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| US8450302B2 (en) | 2002-08-02 | 2013-05-28 | Ab Science | 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors |
| ATE375342T1 (de) | 2002-08-02 | 2007-10-15 | Ab Science | 2-(3-aminoaryl)amino-4-aryl-thiazole und ihre verwendung als c-kit inhibitoren |
| US8153792B2 (en) | 2007-02-13 | 2012-04-10 | Ab Science | Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors |
| US8906357B2 (en) | 2010-04-20 | 2014-12-09 | Ab Science | Treatment of multiple sclerosis with masitinib |
| WO2013010015A2 (en) | 2011-07-13 | 2013-01-17 | Cytokinetics, Inc. | Combination als therapy |
| US10238649B2 (en) * | 2012-10-04 | 2019-03-26 | Ab Science | Use of masitinib for treatment of cancer in patient subpopulations identified using predictor factors |
| EP3388436B1 (en) * | 2013-03-15 | 2020-08-12 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinone compounds and methods of treating disorders |
| US20160263110A1 (en) | 2013-11-04 | 2016-09-15 | Ab Science | Use of masitinib for treatment of amyotrophic lateral sclerosis |
-
2017
- 2017-03-24 CA CA3018635A patent/CA3018635C/en active Active
- 2017-03-24 JP JP2018549902A patent/JP7250312B2/ja active Active
- 2017-03-24 HU HUE17712175A patent/HUE057398T2/hu unknown
- 2017-03-24 ES ES17712175T patent/ES2899929T3/es active Active
- 2017-03-24 SG SG11201808106YA patent/SG11201808106YA/en unknown
- 2017-03-24 SI SI201730997T patent/SI3240538T1/sl unknown
- 2017-03-24 PT PT177121753T patent/PT3240538T/pt unknown
- 2017-03-24 EP EP17712175.3A patent/EP3240538B1/en active Active
- 2017-03-24 PL PL17712175T patent/PL3240538T3/pl unknown
- 2017-03-24 MX MX2018011349A patent/MX390495B/es unknown
- 2017-03-24 BR BR112018069515A patent/BR112018069515A2/pt not_active Application Discontinuation
- 2017-03-24 DK DK17712175.3T patent/DK3240538T3/da active
- 2017-03-24 US US15/545,800 patent/US10092564B2/en active Active
- 2017-03-24 KR KR1020187026871A patent/KR102293847B1/ko active Active
- 2017-03-24 EA EA201800499A patent/EA038531B1/ru unknown
- 2017-03-24 NZ NZ745778A patent/NZ745778A/en not_active IP Right Cessation
- 2017-03-24 AU AU2017236177A patent/AU2017236177B2/en active Active
- 2017-03-24 WO PCT/EP2017/057134 patent/WO2017162884A1/en not_active Ceased
- 2017-03-24 CN CN201780019760.9A patent/CN108883108B/zh active Active
-
2018
- 2018-09-20 IL IL261856A patent/IL261856B/en unknown
-
2021
- 2021-12-16 JP JP2021204244A patent/JP2022037132A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3240538A1 (en) | 2017-11-08 |
| EA038531B1 (ru) | 2021-09-10 |
| PL3240538T3 (pl) | 2022-01-31 |
| KR20180125966A (ko) | 2018-11-26 |
| JP2019515884A (ja) | 2019-06-13 |
| EP3240538B1 (en) | 2021-09-29 |
| MX2018011349A (es) | 2019-02-07 |
| WO2017162884A1 (en) | 2017-09-28 |
| PT3240538T (pt) | 2021-12-07 |
| BR112018069515A2 (pt) | 2019-04-16 |
| JP7250312B2 (ja) | 2023-04-03 |
| AU2017236177A1 (en) | 2018-09-20 |
| US10092564B2 (en) | 2018-10-09 |
| NZ745778A (en) | 2022-07-01 |
| US20180117037A1 (en) | 2018-05-03 |
| IL261856A (en) | 2018-10-31 |
| CN108883108A (zh) | 2018-11-23 |
| KR102293847B1 (ko) | 2021-08-26 |
| DK3240538T3 (da) | 2021-12-06 |
| AU2017236177B2 (en) | 2022-03-31 |
| CA3018635A1 (en) | 2017-09-28 |
| CN108883108B (zh) | 2021-08-06 |
| CA3018635C (en) | 2023-09-26 |
| SG11201808106YA (en) | 2018-10-30 |
| ES2899929T3 (es) | 2022-03-15 |
| JP2022037132A (ja) | 2022-03-08 |
| IL261856B (en) | 2022-04-01 |
| HUE057398T2 (hu) | 2022-05-28 |
| MX390495B (es) | 2025-03-20 |
| EA201800499A1 (ru) | 2019-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI3240538T1 (sl) | Uporaba masitiniba za zdravljenje subpopulacije bolnikov z amiotrofično lateralno sklerozo | |
| IL283086A (en) | Use of cannabidiol in the treatment of tuberous sclerosis complex | |
| MA45192A (fr) | Traitement d'association | |
| HUE060711T2 (hu) | Makrociklusos vegyületek betegségek kezelésére | |
| DK3668509T3 (da) | Fremgangsmåde til behandling af amyotrofisk lateralsklerose med pridopidin | |
| HUE058737T2 (hu) | Eljárások arenaviridae vírusok okozta fertõzések kezelésére | |
| DK3347030T3 (da) | Brug af pasteuriseret akkermansia til behandling af stofskiftesygdomme | |
| EP3347835A4 (en) | PERSONALIZED ENTITY MEMORY | |
| DK3474802T3 (da) | Medicinsk forbinding | |
| HUE056006T2 (hu) | Kombináció Parkinson-kór kezelésére | |
| IL273705B (en) | Benzothiazol compounds and methods using the same for treating neurodegenerative disorders | |
| HUE055263T2 (hu) | 11-Szubsztituált 24-hidroxiszterolok NMDA-hoz kapcsolódó állapotok kezelésére | |
| IL271863B (en) | Compounds and use thereof for the treatment of microbial infections | |
| EP3250367A4 (en) | ACTIVE CALIBRATION | |
| EP3409744A4 (en) | SURFACE TREATMENT AGENT | |
| HUE049413T2 (hu) | Nazális porkészítmény hipoglikémia kezelésére | |
| EP3858943A4 (en) | Surface treatment agent | |
| EP3431566A4 (en) | SURFACE TREATMENT AGENT | |
| IL272375A (en) | Medicinal cannabis | |
| IL268688A (en) | Improved use of botulinum neurotoxin in the treatment of sialorrhea | |
| IL248594B (en) | Ppar gamma agonists for treatment of multiple sclerosis | |
| PL3978074T3 (pl) | Terlipresyna do leczenia zespołu wątrobowo-nerkowego typu 1 | |
| LT3463351T (lt) | Parkinsono ligos gydymas | |
| LT3307267T (lt) | Išsėtinės sklerozės gydymas | |
| HUE064253T2 (hu) | Emulziók hüvelyi fertõzések kezelésére |