ES2899929T3 - Uso de masitinib para el tratamiento de una subpoblación de pacientes con esclerosis lateral amiotrófica - Google Patents

Uso de masitinib para el tratamiento de una subpoblación de pacientes con esclerosis lateral amiotrófica Download PDF

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Publication number
ES2899929T3
ES2899929T3 ES17712175T ES17712175T ES2899929T3 ES 2899929 T3 ES2899929 T3 ES 2899929T3 ES 17712175 T ES17712175 T ES 17712175T ES 17712175 T ES17712175 T ES 17712175T ES 2899929 T3 ES2899929 T3 ES 2899929T3
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ES
Spain
Prior art keywords
inhibitor
als
masitinib
alsfrs
treatment
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Active
Application number
ES17712175T
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English (en)
Spanish (es)
Inventor
Alain Moussy
Jean-Pierre Kinet
Colin Mansfield
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AB Science SA
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AB Science SA
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Publication of ES2899929T3 publication Critical patent/ES2899929T3/es
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES17712175T 2016-03-25 2017-03-24 Uso de masitinib para el tratamiento de una subpoblación de pacientes con esclerosis lateral amiotrófica Active ES2899929T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16162490 2016-03-25
PCT/EP2017/057134 WO2017162884A1 (en) 2016-03-25 2017-03-24 Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation

Publications (1)

Publication Number Publication Date
ES2899929T3 true ES2899929T3 (es) 2022-03-15

Family

ID=55637258

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17712175T Active ES2899929T3 (es) 2016-03-25 2017-03-24 Uso de masitinib para el tratamiento de una subpoblación de pacientes con esclerosis lateral amiotrófica

Country Status (20)

Country Link
US (1) US10092564B2 (OSRAM)
EP (1) EP3240538B1 (OSRAM)
JP (2) JP7250312B2 (OSRAM)
KR (1) KR102293847B1 (OSRAM)
CN (1) CN108883108B (OSRAM)
AU (1) AU2017236177B2 (OSRAM)
BR (1) BR112018069515A2 (OSRAM)
CA (1) CA3018635C (OSRAM)
DK (1) DK3240538T3 (OSRAM)
EA (1) EA038531B1 (OSRAM)
ES (1) ES2899929T3 (OSRAM)
HU (1) HUE057398T2 (OSRAM)
IL (1) IL261856B (OSRAM)
MX (1) MX390495B (OSRAM)
NZ (1) NZ745778A (OSRAM)
PL (1) PL3240538T3 (OSRAM)
PT (1) PT3240538T (OSRAM)
SG (1) SG11201808106YA (OSRAM)
SI (1) SI3240538T1 (OSRAM)
WO (1) WO2017162884A1 (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
EP2911664B1 (en) 2012-10-25 2019-05-08 The General Hospital Corporation Combination therapies for the treatment of alzheimer's disease and related disorders
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
US10188757B2 (en) 2013-10-22 2019-01-29 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
US20190240194A1 (en) * 2016-08-31 2019-08-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
HUE052854T2 (hu) 2016-11-25 2021-05-28 Genuv Inc Készítmény a neurális õssejtek differenciálódásának elõsegítésére és védelmére, továbbá módszer a neurális regeneráció indukálására ugyanennek a segítségével
KR20190128703A (ko) * 2017-03-28 2019-11-18 노파르티스 아게 다발 경화증 치료를 위한 새로운 방법
EP3630110A1 (en) * 2017-05-30 2020-04-08 Deciphera Pharmaceuticals, Inc. Use of 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea and analogs for the treatment of cancers associated with genetic abnormalities in platelet derived growth factor receptoralpha
US11692029B2 (en) 2018-03-05 2023-07-04 The Schepens Eye Research Institute, Inc. Therapy for glaucoma and optic neuropathy by targeting colony stimulating factors
WO2020010049A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation POWDERED FORMULATIONS OF CROMOLYN SODIUM AND α-LACTOSE
CN113727736A (zh) 2018-12-10 2021-11-30 通用医疗公司 色甘酸酯及其用途
CN112618717A (zh) * 2019-09-24 2021-04-09 北京大学深圳研究生院 Btk抑制剂用于治疗肌萎缩侧索硬化症的用途
CN115243681B (zh) * 2019-12-30 2024-08-16 德西费拉制药有限责任公司 1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物
JP2023520580A (ja) 2020-04-06 2023-05-17 ザ ジェネラル ホスピタル コーポレイション コロナウイルス誘発炎症状態の処置方法
WO2025113494A1 (zh) * 2023-11-27 2025-06-05 浙江径科医药有限公司 多环类化合物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW225528B (OSRAM) 1992-04-03 1994-06-21 Ciba Geigy Ag
CO4940418A1 (es) 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
US8450302B2 (en) 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
CA2494695C (en) 2002-08-02 2011-04-05 Ab Science 2-(3-aminoaryl)amino-4-aryl-thiazoles and their use as c-kit inhibitors
CN101657446B (zh) 2007-02-13 2013-05-15 Ab科学有限公司 合成作为激酶抑制剂的2-氨基噻唑化合物的方法
WO2011131705A1 (en) 2010-04-20 2011-10-27 Ab Science Treatment of multiple sclerosis with masitinib
KR101951220B1 (ko) 2011-07-13 2019-02-22 싸이토키네틱스, 인코포레이티드 조합 als 치료법
BR112015007144A2 (pt) * 2012-10-04 2017-12-12 Ab Science uso de masitinib para o tratamento de câncer em subpopulações de paciente identificadas usando fatores prognosticadores
JP6553589B2 (ja) * 2013-03-15 2019-07-31 ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド ピリミド−ジアゼピノン化合物および障害の治療方法
US20160263110A1 (en) * 2013-11-04 2016-09-15 Ab Science Use of masitinib for treatment of amyotrophic lateral sclerosis

Also Published As

Publication number Publication date
PL3240538T3 (pl) 2022-01-31
MX2018011349A (es) 2019-02-07
MX390495B (es) 2025-03-20
IL261856A (en) 2018-10-31
CA3018635A1 (en) 2017-09-28
EA201800499A1 (ru) 2019-03-29
US20180117037A1 (en) 2018-05-03
IL261856B (en) 2022-04-01
EP3240538B1 (en) 2021-09-29
DK3240538T3 (da) 2021-12-06
WO2017162884A1 (en) 2017-09-28
SG11201808106YA (en) 2018-10-30
EA038531B1 (ru) 2021-09-10
US10092564B2 (en) 2018-10-09
KR102293847B1 (ko) 2021-08-26
CN108883108B (zh) 2021-08-06
AU2017236177B2 (en) 2022-03-31
CN108883108A (zh) 2018-11-23
JP2019515884A (ja) 2019-06-13
JP2022037132A (ja) 2022-03-08
EP3240538A1 (en) 2017-11-08
PT3240538T (pt) 2021-12-07
CA3018635C (en) 2023-09-26
AU2017236177A1 (en) 2018-09-20
NZ745778A (en) 2022-07-01
BR112018069515A2 (pt) 2019-04-16
SI3240538T1 (sl) 2022-02-28
KR20180125966A (ko) 2018-11-26
JP7250312B2 (ja) 2023-04-03
HUE057398T2 (hu) 2022-05-28

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