SI3056492T1 - Sol meglumina in njene kristalinične oblike zdravila (delafloksacin) - Google Patents

Sol meglumina in njene kristalinične oblike zdravila (delafloksacin)

Info

Publication number
SI3056492T1
SI3056492T1 SI200532302T SI200532302T SI3056492T1 SI 3056492 T1 SI3056492 T1 SI 3056492T1 SI 200532302 T SI200532302 T SI 200532302T SI 200532302 T SI200532302 T SI 200532302T SI 3056492 T1 SI3056492 T1 SI 3056492T1
Authority
SI
Slovenia
Prior art keywords
delafloxacin
drug
crystalline forms
meglumine salt
meglumine
Prior art date
Application number
SI200532302T
Other languages
English (en)
Inventor
Geoff G. Zhang
Michael F. Bradley
David M. Barnes
Rodger Henry
Original Assignee
Abbvie Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc. filed Critical Abbvie Inc.
Publication of SI3056492T1 publication Critical patent/SI3056492T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18Polyhydroxylic acyclic alcohols
    • C07C31/26Hexahydroxylic alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200532302T 2004-10-08 2005-10-07 Sol meglumina in njene kristalinične oblike zdravila (delafloksacin) SI3056492T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61733404P 2004-10-08 2004-10-08
EP15199355.7A EP3056492B1 (en) 2004-10-08 2005-10-07 Meglumine salt and crystalline forms thereof of a drug (delafloxacin)

Publications (1)

Publication Number Publication Date
SI3056492T1 true SI3056492T1 (sl) 2022-03-31

Family

ID=36129950

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200532302T SI3056492T1 (sl) 2004-10-08 2005-10-07 Sol meglumina in njene kristalinične oblike zdravila (delafloksacin)

Country Status (13)

Country Link
US (8) US7728143B2 (sl)
EP (3) EP3957632A1 (sl)
CA (1) CA2582954C (sl)
CY (1) CY1125048T1 (sl)
DK (1) DK3056492T3 (sl)
ES (1) ES2901955T3 (sl)
HU (1) HUE056718T2 (sl)
LT (1) LT3056492T (sl)
MX (1) MX2007004111A (sl)
PL (1) PL3056492T3 (sl)
PT (1) PT3056492T (sl)
SI (1) SI3056492T1 (sl)
WO (1) WO2006042034A2 (sl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7576216B2 (en) 2004-07-30 2009-08-18 Abbott Laboratories Preparation of pyridonecarboxylic acid antibacterials
HUE056718T2 (hu) * 2004-10-08 2022-03-28 Abbvie Inc Hatóanyag (delafloxacin) meglumin sója és ennek kristályos formái
MX2007012642A (es) * 2005-04-11 2008-01-11 Abbott Lab Composiciones farmaceuticas que tienen perfiles mejorados de disolucion para farmacos poco solubles.
DK2346855T3 (en) 2008-09-24 2017-07-24 Melinta Therapeutics Inc PROCEDURE FOR PREPARING QUINOLONE COMPOSITIONS
JP6063123B2 (ja) 2008-11-15 2017-01-18 メリンタ セラピューティクス、インク 抗菌性組成物
CA2903755A1 (en) * 2013-03-08 2014-09-12 Melinta Therapeutics, Inc. Crystalline forms of d-glucitol, 1-deoxy-1-(methylamino)-, 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate
TW201605447A (zh) * 2014-06-20 2016-02-16 美林塔治療學有限公司 處理感染的方法
TWI732337B (zh) * 2014-06-20 2021-07-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
MX2017006319A (es) 2014-11-14 2017-08-10 Melinta Therapeutics Inc Método para tratar, prevenir o reducir el riesgo de infección cutánea.
CN105693695A (zh) * 2014-11-24 2016-06-22 重庆医药工业研究院有限责任公司 一种德拉沙星葡甲胺盐的晶型及其制备方法
CN106256824B (zh) * 2015-06-18 2020-10-27 重庆医药工业研究院有限责任公司 一种高纯度德拉沙星葡甲胺盐的制备方法
CN105017223B (zh) * 2015-07-08 2017-08-01 扬子江药业集团有限公司 德拉沙星葡甲胺晶型i及其制备方法
CN105017224A (zh) * 2015-07-10 2015-11-04 扬子江药业集团有限公司 一种德拉沙星葡甲胺晶型的制备方法
CN106916142A (zh) * 2015-12-25 2017-07-04 江苏奥赛康药业股份有限公司 一种制备高纯度德拉沙星的方法
CN111718329A (zh) * 2019-03-23 2020-09-29 南京海润医药有限公司 一种德拉沙星杂质iv及产品精制方法
CN111718330A (zh) * 2019-03-23 2020-09-29 南京海润医药有限公司 一种德拉沙星杂质iii及产品精制方法
CN111718331A (zh) * 2019-03-23 2020-09-29 南京海润医药有限公司 德拉沙星的杂质i和ii及产品精制方法
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207994B (it) 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US5578609A (en) 1994-03-25 1996-11-26 The Dupont Merck Pharmaceutical Company 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
ES2177644T3 (es) 1994-04-12 2002-12-16 Arakis Ltd Procedimiento para la resolucion de etodolac utilizando derivados de glucamina.
PT911327E (pt) * 1995-09-22 2002-05-31 Wakunaga Pharma Co Ltd Novos derivados do acido piridonocarboxilico ou seus sais e agente antibacteriano compreendendo os mesmos como o ingrediente activo
EP0945134A1 (de) 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
JP2005097116A (ja) 1999-11-11 2005-04-14 Wakunaga Pharmaceut Co Ltd キノリンカルボン酸誘導体アルカリ金属塩及びこれを用いたキノリンカルボン酸誘導体の精製法
GB9929037D0 (en) * 1999-12-08 2000-02-02 Glaxo Wellcome Spa Heterocyclic derivatives
JP2003522165A (ja) 2000-01-31 2003-07-22 ファイザー・プロダクツ・インク Pde4アイソザイムの阻害剤として有用なピリミジンカルボキサミド
JP4337283B2 (ja) 2001-07-11 2009-09-30 ソニー株式会社 光ピックアップ装置及び記録及び/又は再生装置
JP4290381B2 (ja) 2002-04-11 2009-07-01 学校法人 聖マリアンナ医科大学 ピリドンカルボン酸化合物含有エマルション
JP2004168772A (ja) 2002-11-06 2004-06-17 Takeda Chem Ind Ltd 受容体調節剤
HUE056718T2 (hu) * 2004-10-08 2022-03-28 Abbvie Inc Hatóanyag (delafloxacin) meglumin sója és ennek kristályos formái

Also Published As

Publication number Publication date
CA2582954A1 (en) 2006-04-20
US20140155380A1 (en) 2014-06-05
CA2582954C (en) 2014-07-29
US8969569B2 (en) 2015-03-03
CY1125048T1 (el) 2023-06-09
JP2008515910A (ja) 2008-05-15
PT3056492T (pt) 2021-12-27
JP5294633B2 (ja) 2013-09-18
US20130060040A1 (en) 2013-03-07
US20170073329A1 (en) 2017-03-16
LT3056492T (lt) 2022-01-25
US9873681B2 (en) 2018-01-23
HUE056718T2 (hu) 2022-03-28
US20100261703A1 (en) 2010-10-14
US20180105510A1 (en) 2018-04-19
US20100286397A1 (en) 2010-11-11
MX2007004111A (es) 2007-06-14
US8273892B2 (en) 2012-09-25
EP1802607A2 (en) 2007-07-04
WO2006042034A8 (en) 2007-09-07
DK3056492T3 (da) 2021-12-13
EP3056492B1 (en) 2021-09-22
ES2901955T3 (es) 2022-03-24
US20150196547A1 (en) 2015-07-16
US7728143B2 (en) 2010-06-01
US8648093B2 (en) 2014-02-11
US9539250B2 (en) 2017-01-10
EP3957632A1 (en) 2022-02-23
US8252813B2 (en) 2012-08-28
WO2006042034A2 (en) 2006-04-20
US20070043019A1 (en) 2007-02-22
US10329276B2 (en) 2019-06-25
EP3056492A1 (en) 2016-08-17
WO2006042034A3 (en) 2006-06-22
PL3056492T3 (pl) 2022-03-21

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