SI2550286T1 - Kristalne oblike makrolida in njihove uporabe - Google Patents

Kristalne oblike makrolida in njihove uporabe

Info

Publication number
SI2550286T1
SI2550286T1 SI201130745T SI201130745T SI2550286T1 SI 2550286 T1 SI2550286 T1 SI 2550286T1 SI 201130745 T SI201130745 T SI 201130745T SI 201130745 T SI201130745 T SI 201130745T SI 2550286 T1 SI2550286 T1 SI 2550286T1
Authority
SI
Slovenia
Prior art keywords
macrolide
crystalline forms
uses therefor
therefor
crystalline
Prior art date
Application number
SI201130745T
Other languages
English (en)
Slovenian (sl)
Inventor
David E. Pereira
Original Assignee
Cempra Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44673574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2550286(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cempra Pharmaceuticals, Inc. filed Critical Cempra Pharmaceuticals, Inc.
Publication of SI2550286T1 publication Critical patent/SI2550286T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI201130745T 2010-03-22 2011-03-22 Kristalne oblike makrolida in njihove uporabe SI2550286T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31606310P 2010-03-22 2010-03-22
PCT/US2011/029424 WO2011119604A1 (en) 2010-03-22 2011-03-22 Crystalline forms of a macrolide, and uses therefor
EP11760068.4A EP2550286B1 (en) 2010-03-22 2011-03-22 Crystalline forms of a macrolide, and uses therefor

Publications (1)

Publication Number Publication Date
SI2550286T1 true SI2550286T1 (sl) 2016-04-29

Family

ID=44673574

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201130745T SI2550286T1 (sl) 2010-03-22 2011-03-22 Kristalne oblike makrolida in njihove uporabe

Country Status (19)

Country Link
US (4) US8975386B2 (OSRAM)
EP (2) EP2550286B1 (OSRAM)
JP (4) JP5711352B2 (OSRAM)
KR (2) KR102006200B1 (OSRAM)
CN (2) CN103080122A (OSRAM)
AU (2) AU2011232627B2 (OSRAM)
BR (1) BR112012023950A2 (OSRAM)
CA (1) CA2793884C (OSRAM)
DK (1) DK2550286T3 (OSRAM)
ES (1) ES2564097T3 (OSRAM)
HR (1) HRP20160168T1 (OSRAM)
IL (1) IL222018B (OSRAM)
MX (1) MX361413B (OSRAM)
MY (1) MY162411A (OSRAM)
NZ (1) NZ602544A (OSRAM)
PL (1) PL2550286T3 (OSRAM)
RU (1) RU2650883C2 (OSRAM)
SI (1) SI2550286T1 (OSRAM)
WO (1) WO2011119604A1 (OSRAM)

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EP3738591A3 (en) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US9072759B2 (en) 2008-10-24 2015-07-07 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
ES2564097T3 (es) * 2010-03-22 2016-03-17 Cempra Pharmaceuticals, Inc. Formas cristalinas de un macrólido, y usos de las mismas
ES2636948T3 (es) 2010-05-20 2017-10-10 Cempra Pharmaceuticals, Inc. Procesos para preparar macrólidos y cetólidos e intermediarios para los mismos
WO2012034058A1 (en) 2010-09-10 2012-03-15 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
IN2014DN08939A (OSRAM) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
MX377459B (es) 2013-04-04 2025-03-10 Harvard College Macrolidos y metodos para su preparacion y uso.
CA2957034A1 (en) * 2014-08-05 2016-02-11 Cempra Pharmaceuticals, Inc. Powder oral suspension formulations of antibacterial agents
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CN104311611B (zh) * 2014-08-13 2017-01-18 广东东阳光药业有限公司 一种制备固态大环内酯的方法
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
CN107530365A (zh) 2015-03-25 2018-01-02 哈佛大学的校长及成员们 具有修饰的脱氧糖胺糖的大环内酯及其用途
WO2017061431A1 (ja) * 2015-10-05 2017-04-13 富山化学工業株式会社 ソリスロマイシンを含む錠剤
EP3190122A1 (en) * 2016-01-08 2017-07-12 LEK Pharmaceuticals d.d. A novel synthetic pathway towards solithromycin and purification thereof
WO2018045294A1 (en) * 2016-09-02 2018-03-08 Cempra Pharmaceuticals, Inc. Processes for preparing fluoroketolides
AU2020395150A1 (en) * 2019-12-02 2022-06-23 AliquantumRx, Inc. Salts and polymorphs of cethromycin for the treatment of disease salts and polymorphs of cethromycin

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Also Published As

Publication number Publication date
IL222018B (en) 2019-05-30
RU2650883C2 (ru) 2018-04-18
EP3009442A1 (en) 2016-04-20
MX361413B (es) 2018-12-05
JP6121387B2 (ja) 2017-04-26
PL2550286T3 (pl) 2016-07-29
EP2550286B1 (en) 2015-12-09
AU2011232627A1 (en) 2012-10-18
US8975386B2 (en) 2015-03-10
DK2550286T3 (en) 2016-02-29
US8759500B2 (en) 2014-06-24
AU2016203986B2 (en) 2016-10-06
US20130018008A1 (en) 2013-01-17
MY162411A (en) 2017-06-15
RU2012144614A (ru) 2014-04-27
EP3009442B1 (en) 2019-06-19
HK1177937A1 (en) 2013-08-30
EP2550286A4 (en) 2013-10-02
KR20130056226A (ko) 2013-05-29
JP2013522367A (ja) 2013-06-13
US20190040096A1 (en) 2019-02-07
MX2012010895A (es) 2013-02-15
US20160244472A1 (en) 2016-08-25
CN108570083A (zh) 2018-09-25
EP2550286A1 (en) 2013-01-30
JP5711352B2 (ja) 2015-04-30
AU2016203986A1 (en) 2016-06-30
CA2793884C (en) 2019-09-10
KR20180101643A (ko) 2018-09-12
CA2793884A1 (en) 2011-09-29
ES2564097T3 (es) 2016-03-17
BR112012023950A2 (pt) 2016-07-05
AU2011232627B2 (en) 2016-03-17
CN103080122A (zh) 2013-05-01
US20130252915A1 (en) 2013-09-26
JP2017081953A (ja) 2017-05-18
WO2011119604A1 (en) 2011-09-29
JP2015063536A (ja) 2015-04-09
HRP20160168T1 (hr) 2016-03-25
NZ602544A (en) 2014-11-28
KR102006200B1 (ko) 2019-08-01
JP2020002168A (ja) 2020-01-09

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