SI2226381T1 - Postopek za gojenje celic za proizvodnjo snovi - Google Patents

Postopek za gojenje celic za proizvodnjo snovi

Info

Publication number
SI2226381T1
SI2226381T1 SI200332473A SI200332473A SI2226381T1 SI 2226381 T1 SI2226381 T1 SI 2226381T1 SI 200332473 A SI200332473 A SI 200332473A SI 200332473 A SI200332473 A SI 200332473A SI 2226381 T1 SI2226381 T1 SI 2226381T1
Authority
SI
Slovenia
Prior art keywords
glucose
limitation
dgl
qglc
cells
Prior art date
Application number
SI200332473A
Other languages
English (en)
Slovenian (sl)
Inventor
Ruth Essers
Jochen Gaetgens
Thomas Link
Thomas Noll
Kerstin Skopnik
Christian Wandrey
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2226381T1 publication Critical patent/SI2226381T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI200332473A 2002-11-27 2003-11-07 Postopek za gojenje celic za proizvodnjo snovi SI2226381T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10255508A DE10255508A1 (de) 2002-11-27 2002-11-27 Verfahren zur Kultivierung von Zellen zur Produktion von Substanzen
EP10152393.4A EP2226381B1 (de) 2002-11-27 2003-11-07 Verfahren zur kultivierung von zellen zur produktion von substanzen

Publications (1)

Publication Number Publication Date
SI2226381T1 true SI2226381T1 (sl) 2016-05-31

Family

ID=32318751

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200332473A SI2226381T1 (sl) 2002-11-27 2003-11-07 Postopek za gojenje celic za proizvodnjo snovi
SI200331791T SI1585810T1 (sl) 2002-11-27 2003-11-07 Postopek gojenja celic za proizvodnjo substanc
SI200332602T SI2275530T1 (sl) 2002-11-27 2003-11-07 Postopek za gojenje celic za proizvodnjo snovi

Family Applications After (2)

Application Number Title Priority Date Filing Date
SI200331791T SI1585810T1 (sl) 2002-11-27 2003-11-07 Postopek gojenja celic za proizvodnjo substanc
SI200332602T SI2275530T1 (sl) 2002-11-27 2003-11-07 Postopek za gojenje celic za proizvodnjo snovi

Country Status (12)

Country Link
US (2) US20060127975A1 (enExample)
EP (3) EP1585810B1 (enExample)
JP (2) JP4469283B2 (enExample)
AT (1) ATE462013T1 (enExample)
CY (2) CY1110267T1 (enExample)
DE (2) DE10255508A1 (enExample)
DK (2) DK1585810T3 (enExample)
ES (3) ES2749217T3 (enExample)
HU (1) HUE028862T2 (enExample)
PT (1) PT1585810E (enExample)
SI (3) SI2226381T1 (enExample)
WO (1) WO2004048556A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2284271C (en) 1997-03-21 2012-05-08 Chugai Seiyaku Kabushiki Kaisha A preventive or therapeutic agent for sensitized t cell-mediated diseases comprising il-6 antagonist as an active ingredient
UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
SI1623019T1 (sl) * 2003-05-15 2010-10-29 Wyeth Llc Omejeno glukozno dovajanje za živalsko celično kulturo
PE20091174A1 (es) 2007-12-27 2009-08-03 Chugai Pharmaceutical Co Ltd Formulacion liquida con contenido de alta concentracion de anticuerpo
DE102008002210A1 (de) * 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Erythropoietin
AU2016210748B2 (en) * 2009-10-26 2018-03-01 Chugai Seiyaku Kabushiki Kaisha Method for the production of a glycosylated immunoglobulin
ES2981683T3 (es) * 2009-10-26 2024-10-10 Hoffmann La Roche Procedimiento para la producción de una inmunoglobulina glucosilada
AU2015203309B2 (en) * 2009-10-26 2016-05-05 Chugai Seiyaku Kabushiki Kaisha Method for the production of a glycosylated immunoglobulin
TWI563090B (en) * 2009-12-22 2016-12-21 Dsm Ip Assets Bv The preparation of caprolactam from 6-amino caproic acid obtained in a fermentation process
KR20130086628A (ko) 2010-11-08 2013-08-02 제넨테크, 인크. 피하 투여용 항―il―6 수용체 항체
JP6563910B2 (ja) 2013-07-04 2019-08-21 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ
EP3119876B1 (en) 2014-03-19 2024-12-18 Pfizer Inc. Method of cell culture
ES2989780T3 (es) 2015-09-23 2024-11-27 Pfizer Células y procedimiento de cultivo celular
US20220073942A1 (en) 2018-12-06 2022-03-10 Pfizer Inc. Cells with reduced inhibitor production and methods of use thereof
WO2025088516A1 (en) 2023-10-26 2025-05-01 Pfizer Inc. Method of forming multi-specific antibodies from homodimer antibodies and pharmaceutical product including multi-specific antibodies thus obtained

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657863A (en) * 1982-07-02 1987-04-14 Celanese Corporation Stabilization of a mutant microorganism population
JPH066054B2 (ja) * 1987-10-15 1994-01-26 帝人株式会社 動物細胞の培養方法
ATE125157T1 (de) * 1990-04-03 1995-08-15 Genentech Inc Methoden und zusammensetzungen zur impfung gegen hiv.
GB9022545D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Culture medium
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
CA2111561A1 (en) 1992-05-01 1993-11-11 Yoshiharu Takazawa Fed batch culture method for protein secreting cells
GB9506249D0 (en) * 1995-03-27 1995-05-17 Karobio Ab Media for insect cell cultures
US6156570A (en) * 1997-03-20 2000-12-05 Regents Of The University Of Minnesota Process for the continuous culture of cells
US6338964B1 (en) * 1999-05-07 2002-01-15 Bayer Corporation Process and medium for mammalian cell culture under low dissolved carbon dioxide concentration

Also Published As

Publication number Publication date
US20140329277A1 (en) 2014-11-06
SI2275530T1 (sl) 2019-11-29
ES2340377T3 (es) 2010-06-02
ES2567161T3 (es) 2016-04-20
EP2275530A2 (de) 2011-01-19
CY1117558T1 (el) 2017-04-26
DE10255508A1 (de) 2004-06-17
EP2226381B1 (de) 2016-03-09
WO2004048556A1 (de) 2004-06-10
EP1585810B1 (de) 2010-03-24
EP2275530A3 (de) 2012-05-23
JP2010110331A (ja) 2010-05-20
CY1110267T1 (el) 2015-01-14
SI1585810T1 (sl) 2010-06-30
PT1585810E (pt) 2010-05-05
EP2275530B1 (de) 2019-08-07
EP1585810A1 (de) 2005-10-19
DK2226381T3 (en) 2016-04-11
JP2006507821A (ja) 2006-03-09
ES2749217T3 (es) 2020-03-19
HUE028862T2 (en) 2017-01-30
DK1585810T3 (da) 2010-06-07
JP5221573B2 (ja) 2013-06-26
DE50312554D1 (de) 2010-05-06
US20060127975A1 (en) 2006-06-15
ATE462013T1 (de) 2010-04-15
EP2226381A1 (de) 2010-09-08
JP4469283B2 (ja) 2010-05-26

Similar Documents

Publication Publication Date Title
CY1117558T1 (el) Μεθοδος για καλλιεργεια κυτταρων για παραγωγη ουσιων
DK1623019T3 (da) Begrænset glucosetilførsel til dyrecellekultur
YU61799A (sh) Postupak za fermentacionu proizvodnju d-pantotenske kiseline pomoću pojačanja pan d-gena u mikroorganizmima
YU55100A (sh) Postupak za fermentacionu proizvodnju d-pantotenske kiseline upotrebom bakterija korinskog oblika
DE602004014158D1 (de) Verfahren zur herstellung von l-lysin oder l-threonin unter verwendung von escherichia-bakterien mit abgeschwächter malatenzymaktivität
BRPI0516261A (pt) método para produzir uma substãncia básica por fermentação, e, caldo de fermentação ou produto de fermentação contendo uma substáncia básica
BR0200285A (pt) Bactéria corineforme, e método para a produção de l-cisteìna
TR200401091T4 (tr) Gelişim faktörleri ve L-glutamin içeren hücre kültürü besiyeri
IL160445A0 (en) A unit and a process for carrying out high cell density fermentation
EP4406615A3 (en) Method for the production of a glycosylated immunoglobulin
DK1085083T3 (da) Dyrkningsmedium for dyreceller og fremgangsmåde til proteinfremstilling under anvendelse af dette
DE60138127D1 (de) Stoffwechseländerungen in gärungen zur produktion rekombinanter proteine
UA92157C2 (ru) Способ продуцирования гормона роста
EP1687413B8 (en) Method for differentiating mesenchymal stem cell into neural cell and pharmaceutical composition containing the neural cell for neurodegenerative disease
ATE317442T1 (de) Verfahren zur züchtung von mikroorganismen die methanol metabolisieren
WO2004029260A3 (en) Astaxanthin production using fed-batch fermentation process by phaffia rhodozyma
ATE386134T1 (de) Verfahren zur herstellung von glutathion
PT1212448E (pt) Processo de producao de exopolissacaridos
AU2001243667A1 (en) Method of aerating yeast prior to pitching
AU2003273521A1 (en) Production method of iturin a and its homologues
WO2001020016A3 (de) Verfahren zur steigerung der ausbeute von rekombinanten proteinen in mikrobiellen fermentationsprozessen
AU2002214085A1 (en) Method for producing proteins by electroporation
DE50013563D1 (de) Verwendung von pankreatischer Procarboxypeptidase B zur Herstellung von Insulin
AU2003242533A1 (en) Glutamine-free medium
EP1477555A3 (en) Method for culturing bacterial cells belonging to the enterococcus genus and method of producing killed bacterial cells belonging to the enterococcus genus