SI21655A - Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida - Google Patents

Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida Download PDF

Info

Publication number
SI21655A
SI21655A SI200300320A SI200300320A SI21655A SI 21655 A SI21655 A SI 21655A SI 200300320 A SI200300320 A SI 200300320A SI 200300320 A SI200300320 A SI 200300320A SI 21655 A SI21655 A SI 21655A
Authority
SI
Slovenia
Prior art keywords
aminopropyl
synthesis
methoxybenzenesulfonamide
tamsulosin
group
Prior art date
Application number
SI200300320A
Other languages
English (en)
Slovenian (sl)
Inventor
Barbara Mohar
Original Assignee
LEK farmacevtska dru�ba d.d.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LEK farmacevtska dru�ba d.d. filed Critical LEK farmacevtska dru�ba d.d.
Priority to SI200300320A priority Critical patent/SI21655A/sl
Priority to SI200431679T priority patent/SI1704140T1/sl
Priority to RU2006127298/04A priority patent/RU2419605C2/ru
Priority to DE602004031879T priority patent/DE602004031879D1/de
Priority to CN2004800394296A priority patent/CN1902165B/zh
Priority to CA2549604A priority patent/CA2549604C/en
Priority to PCT/SI2004/000046 priority patent/WO2005063701A1/en
Priority to AU2004309314A priority patent/AU2004309314B2/en
Priority to AT04809254T priority patent/ATE502007T1/de
Priority to EP04809254A priority patent/EP1704140B1/en
Priority to JP2006546936A priority patent/JP4695095B2/ja
Priority to BRPI0418219-7A priority patent/BRPI0418219A/pt
Priority to US10/584,369 priority patent/US7538246B2/en
Publication of SI21655A publication Critical patent/SI21655A/sl
Priority to ZA200604812A priority patent/ZA200604812B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
    • C07C303/08—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with halogenosulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200300320A 2003-12-29 2003-12-29 Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida SI21655A (sl)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SI200300320A SI21655A (sl) 2003-12-29 2003-12-29 Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida
AU2004309314A AU2004309314B2 (en) 2003-12-29 2004-12-27 Synthesis of optically pure (R)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
AT04809254T ATE502007T1 (de) 2003-12-29 2004-12-27 Synthese von optisch reinem (r)-5-(2-aminopropyl)-2-methoxybenzolsulphonami
DE602004031879T DE602004031879D1 (en) 2003-12-29 2004-12-27 Synthese von optisch reinem (r)-5-(2-aminopropyl)-2-methoxybenzolsulphonamid
CN2004800394296A CN1902165B (zh) 2003-12-29 2004-12-27 光学纯(r)-5-(2-氨基丙基)-2-甲氧基苯磺酰胺的合成
CA2549604A CA2549604C (en) 2003-12-29 2004-12-27 Synthesis of optically pure (r)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
PCT/SI2004/000046 WO2005063701A1 (en) 2003-12-29 2004-12-27 Synthesis of optically pure (r)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
SI200431679T SI1704140T1 (sl) 2003-12-29 2004-12-27 Postopek za pripravo (R)-5-(2-aminopril)-2-metoksibenzensulfonamida
RU2006127298/04A RU2419605C2 (ru) 2003-12-29 2004-12-27 Синтез оптически чистого (r)-5-(2-аминопропил)-2-метоксибензолсульфонамида
EP04809254A EP1704140B1 (en) 2003-12-29 2004-12-27 Synthesis of optically pure (r)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
JP2006546936A JP4695095B2 (ja) 2003-12-29 2004-12-27 光学的に純粋な（ｒ）−５−（２−アミノプロピル）−２−メトキシベンゼンスルホンアミドの合成
BRPI0418219-7A BRPI0418219A (pt) 2003-12-29 2004-12-27 sìntese de (r)-5-(2-aminopropil)-2-metoxibenzenossulfonamida opticamente pura
US10/584,369 US7538246B2 (en) 2003-12-29 2004-12-27 Synthesis of optically pure(r)-5-(2-amynopropyl)-2-methoxybenzenesulphonamide
ZA200604812A ZA200604812B (en) 2003-12-29 2006-06-12 Synthesis of optically pure (R)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200300320A SI21655A (sl) 2003-12-29 2003-12-29 Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida

Publications (1)

Publication Number Publication Date
SI21655A true SI21655A (sl) 2005-06-30

Family

ID=34738130

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200300320A SI21655A (sl) 2003-12-29 2003-12-29 Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida
SI200431679T SI1704140T1 (sl) 2003-12-29 2004-12-27 Postopek za pripravo (R)-5-(2-aminopril)-2-metoksibenzensulfonamida

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200431679T SI1704140T1 (sl) 2003-12-29 2004-12-27 Postopek za pripravo (R)-5-(2-aminopril)-2-metoksibenzensulfonamida

Country Status (13)

Country Link
US (1) US7538246B2 (zh)
EP (1) EP1704140B1 (zh)
JP (1) JP4695095B2 (zh)
CN (1) CN1902165B (zh)
AT (1) ATE502007T1 (zh)
AU (1) AU2004309314B2 (zh)
BR (1) BRPI0418219A (zh)
CA (1) CA2549604C (zh)
DE (1) DE602004031879D1 (zh)
RU (1) RU2419605C2 (zh)
SI (2) SI21655A (zh)
WO (1) WO2005063701A1 (zh)
ZA (1) ZA200604812B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101284807B (zh) * 2008-06-11 2010-12-08 药源药物化学（上海）有限公司 盐酸坦索罗辛的制备方法
CN102898336B (zh) * 2012-10-16 2013-11-27 北京悦康科创医药科技有限公司 一种盐酸坦索罗辛的制备方法
MX2017003290A (es) * 2014-09-16 2017-06-21 Shionogi & Co Proceso para la preparacion de derivados de trifenilbuteno.
BR112018017117B1 (pt) 2016-03-15 2021-11-16 Shionogi & Co., Ltd. Metodo de produqao para derivados de fenoxietanol
CN110156643A (zh) * 2019-06-24 2019-08-23 新乡市锦源化工有限公司 一种对乙酰氨基苯磺酰氯高效催化制备方法
CN113582947B (zh) * 2021-09-07 2023-06-20 南开大学 一种脱除胺的磺酰基保护的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860647A (en) * 1973-08-20 1975-01-14 Smithkline Corp {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
JPS62114952A (ja) * 1985-11-13 1987-05-26 Yamanouchi Pharmaceut Co Ltd 置換フエネチルアミン誘導体の製造法
JP2696363B2 (ja) * 1988-02-19 1998-01-14 北陸製薬株式会社 フェノキシエチルアミン誘導体
CZ20013848A3 (cs) * 2001-10-25 2003-05-14 Léčiva, A.S. Způsob výroby (R)-(-)-5-[2-[2-(2-ethoxyfenoxy)ethylamino]propyl]-2-methoxybenzensulfonamidu

Also Published As

Publication number Publication date
SI1704140T1 (sl) 2011-10-28
ZA200604812B (en) 2007-09-26
EP1704140B1 (en) 2011-03-16
RU2006127298A (ru) 2008-02-10
JP4695095B2 (ja) 2011-06-08
CA2549604A1 (en) 2005-07-14
DE602004031879D1 (en) 2011-04-28
EP1704140A1 (en) 2006-09-27
ATE502007T1 (de) 2011-04-15
JP2007517796A (ja) 2007-07-05
US20070155989A1 (en) 2007-07-05
CA2549604C (en) 2012-09-18
CN1902165A (zh) 2007-01-24
US7538246B2 (en) 2009-05-26
AU2004309314A1 (en) 2005-07-14
WO2005063701A1 (en) 2005-07-14
AU2004309314B2 (en) 2011-09-01
RU2419605C2 (ru) 2011-05-27
CN1902165B (zh) 2010-06-16
BRPI0418219A (pt) 2007-04-27

Similar Documents

Publication Publication Date Title
KR100220266B1 (ko) 광학 활성 2차 아민 화합물, 이의 제조방법 및 이를 이용한 광학 활성 카르복실산의 제조방법
US7737303B2 (en) Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof
US9944599B2 (en) Processes for the preparation of beta-aminosulfone compounds
TW514634B (en) Process to make chiral compounds
ZA200604812B (en) Synthesis of optically pure (R)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
CA1269997A (en) Racemization process
EP1828110B1 (en) Process for the preparation of tamsulosin and intermediates thereof
ZA200604240B (en) Preparation of r-5-(2-(2-ethoxyphenoxyetylamino)propyl)-2-methoxybenzenesulphonamide hydrochloride of high chemical purity
CN100371320C (zh) S-芳基-半胱氨酸及其衍生物的制备方法
CA2356855A1 (en) Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
EP2674414A1 (en) Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds
FR2669333A1 (fr) Procede de separation des enantiomeres des 5-aryl-5-alkylhydantouines.
EP1697316B1 (en) Novel intermediates for the synthesis of (r)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation
MXPA06007482A (en) Synthesis of optically pure (r)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide
CA2407103A1 (en) Process and intermediates for the preparation of 1-(9h-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol, carvedilol or acid addition salts thereof
US20060079714A1 (en) Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation
EP1539684B1 (en) Benzenesulphonamides and process for their preparation
AU2003211537A1 (en) Novel crystals of 5-hydroxycarbamimidoyl-2-hydroxybenzenesulfonamide derivative
JP2004155696A (ja) 光学活性２−アミノ−２−フェニルエタノール類の製造方法およびその中間体
WO2007037242A1 (ja) 光学活性ベンジルアミン誘導体の製造方法
MXPA06007477A (en) Preparation of r-5-(2-(2-ethoxyphenoxyetylamino)propyl)-2- methoxybenzenesulphonamide hydrochloride of high chemical
JP2006528167A (ja) イミン中間体の製法
JP2004083457A (ja) 光学活性２−アミノ−２−フェニルエタノール類の製造法およびその中間体
IE55651B1 (en) Process for producing and separating diastereomeric urea derivatives

Legal Events

Date Code Title Description
OO00 Grant of patent

Effective date: 20040517

KO00 Lapse of patent

Effective date: 20130808