SI2139490T1 - Diazo bicikliäśni smac mimeti in njih uporaba - Google Patents

Diazo bicikliäśni smac mimeti in njih uporaba

Info

Publication number
SI2139490T1
SI2139490T1 SI200831285T SI200831285T SI2139490T1 SI 2139490 T1 SI2139490 T1 SI 2139490T1 SI 200831285 T SI200831285 T SI 200831285T SI 200831285 T SI200831285 T SI 200831285T SI 2139490 T1 SI2139490 T1 SI 2139490T1
Authority
SI
Slovenia
Prior art keywords
smac mimetics
diazo bicyclic
bicyclic smac
diazo
mimetics
Prior art date
Application number
SI200831285T
Other languages
English (en)
Slovenian (sl)
Inventor
Shaomeng Wang
Yuefeng Peng
Haiying Sun
Qian Cai
Zaneta Nikolovska-Coleska
Jianfeng Lu
Su Qiu
Original Assignee
The Regents Of The University Of Mchigan Office Of Technology Transfer, University Of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39864640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2139490(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Regents Of The University Of Mchigan Office Of Technology Transfer, University Of Michigan filed Critical The Regents Of The University Of Mchigan Office Of Technology Transfer, University Of Michigan
Publication of SI2139490T1 publication Critical patent/SI2139490T1/sl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
SI200831285T 2007-04-13 2008-04-14 Diazo bicikliäśni smac mimeti in njih uporaba SI2139490T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92334807P 2007-04-13 2007-04-13
EP08745750.3A EP2139490B1 (en) 2007-04-13 2008-04-14 Diazo bicyclic smac mimetics and the uses thereof
PCT/US2008/060215 WO2008128171A2 (en) 2007-04-13 2008-04-14 Diazo bicyclic smac mimetics and the uses thereof

Publications (1)

Publication Number Publication Date
SI2139490T1 true SI2139490T1 (sl) 2014-11-28

Family

ID=39864640

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831285T SI2139490T1 (sl) 2007-04-13 2008-04-14 Diazo bicikliäśni smac mimeti in njih uporaba

Country Status (22)

Country Link
US (2) US8278293B2 (OSRAM)
EP (1) EP2139490B1 (OSRAM)
JP (1) JP5416089B2 (OSRAM)
KR (1) KR101081685B1 (OSRAM)
CN (1) CN101686981B (OSRAM)
AU (1) AU2008240119B2 (OSRAM)
BR (1) BRPI0810522B8 (OSRAM)
CA (1) CA2683318C (OSRAM)
CY (1) CY1115735T1 (OSRAM)
DK (1) DK2139490T3 (OSRAM)
EA (1) EA017797B1 (OSRAM)
ES (1) ES2504216T3 (OSRAM)
HR (1) HRP20140885T1 (OSRAM)
HU (1) HUE024142T2 (OSRAM)
IL (1) IL201474A (OSRAM)
MX (1) MX2009011069A (OSRAM)
NZ (1) NZ580468A (OSRAM)
PL (1) PL2139490T3 (OSRAM)
PT (1) PT2139490E (OSRAM)
SI (1) SI2139490T1 (OSRAM)
WO (1) WO2008128171A2 (OSRAM)
ZA (1) ZA200907055B (OSRAM)

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EP2491041B1 (en) 2009-10-23 2017-08-09 The Regents of the University of Michigan Bivalent diazo bicyclic smac mimetics and the uses thereof
KR20120101050A (ko) * 2009-11-05 2012-09-12 더 유에이비 리서치 파운데이션 기저형 유전자형 암의 치료 방법
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GB201610147D0 (en) 2016-06-10 2016-07-27 Glaxosmithkline Ip Dev Ltd Novel compounds
KR20230127371A (ko) 2016-11-01 2023-08-31 아비나스 오퍼레이션스, 인코포레이티드 타우(Tau)-단백질 표적화 프로탁(PROTAC) 및 관련 사용 방법
IL297717A (en) 2016-12-01 2022-12-01 Arvinas Operations Inc History of tetrahydronaphthalene and tetrahydroisoquinoline as estrogen receptor antagonists
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MX2019007649A (es) 2016-12-23 2019-09-10 Arvinas Operations Inc Compuestos y metodos para la degradacion dirigida de polipeptidos de fibrosarcoma acelerado rapidamente.
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Also Published As

Publication number Publication date
CY1115735T1 (el) 2017-01-25
AU2008240119A1 (en) 2008-10-23
WO2008128171A3 (en) 2008-12-11
IL201474A (en) 2015-11-30
DK2139490T3 (da) 2014-09-08
BRPI0810522B1 (pt) 2020-02-04
NZ580468A (en) 2012-02-24
US8278293B2 (en) 2012-10-02
WO2008128171A2 (en) 2008-10-23
BRPI0810522A2 (pt) 2014-10-21
EA017797B1 (ru) 2013-03-29
EA200901400A1 (ru) 2010-04-30
US8664212B2 (en) 2014-03-04
HRP20140885T1 (hr) 2014-11-21
KR20100005213A (ko) 2010-01-14
IL201474A0 (en) 2010-05-31
CA2683318C (en) 2012-10-30
HUE024142T2 (en) 2016-02-29
MX2009011069A (es) 2009-12-03
CN101686981B (zh) 2013-04-10
JP5416089B2 (ja) 2014-02-12
EP2139490A4 (en) 2010-10-27
AU2008240119B2 (en) 2012-04-05
EP2139490B1 (en) 2014-07-02
KR101081685B1 (ko) 2011-11-09
PT2139490E (pt) 2014-10-08
US20120309961A1 (en) 2012-12-06
ES2504216T3 (es) 2014-10-08
CA2683318A1 (en) 2008-10-23
PL2139490T3 (pl) 2014-11-28
ZA200907055B (en) 2011-03-30
BRPI0810522B8 (pt) 2021-05-25
US20100273812A1 (en) 2010-10-28
JP2010523722A (ja) 2010-07-15
HK1141456A1 (en) 2010-11-12
EP2139490A2 (en) 2010-01-06
CN101686981A (zh) 2010-03-31

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