SI1963278T1 - Substituirani imidazolinski derivati - Google Patents

Substituirani imidazolinski derivati

Info

Publication number
SI1963278T1
SI1963278T1 SI200630546T SI200630546T SI1963278T1 SI 1963278 T1 SI1963278 T1 SI 1963278T1 SI 200630546 T SI200630546 T SI 200630546T SI 200630546 T SI200630546 T SI 200630546T SI 1963278 T1 SI1963278 T1 SI 1963278T1
Authority
SI
Slovenia
Prior art keywords
alkyl
aryl
saturated
optionally substituted
imidazoline derivatives
Prior art date
Application number
SI200630546T
Other languages
English (en)
Slovenian (sl)
Inventor
Beatrix Merla
Stefan Oberborsch
Bernd Sundermann
Werner Englberger
Hagen-Heinrich Hennies
Heinz Graubaum
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of SI1963278T1 publication Critical patent/SI1963278T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI200630546T 2005-12-22 2006-12-19 Substituirani imidazolinski derivati SI1963278T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005061430A DE102005061430A1 (de) 2005-12-22 2005-12-22 Substituierte Imidazolin-Derivate
EP06841028A EP1963278B1 (de) 2005-12-22 2006-12-19 Substituierte imidazolin-derivate

Publications (1)

Publication Number Publication Date
SI1963278T1 true SI1963278T1 (sl) 2010-03-31

Family

ID=37946192

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200630546T SI1963278T1 (sl) 2005-12-22 2006-12-19 Substituirani imidazolinski derivati

Country Status (17)

Country Link
US (1) US7728028B2 (enExample)
EP (1) EP1963278B1 (enExample)
JP (1) JP2009523124A (enExample)
CN (1) CN101384557A (enExample)
AT (1) ATE449075T1 (enExample)
AU (1) AU2006334743B2 (enExample)
CA (1) CA2633918A1 (enExample)
CY (1) CY1110465T1 (enExample)
DE (2) DE102005061430A1 (enExample)
DK (1) DK1963278T3 (enExample)
ES (1) ES2336833T3 (enExample)
IL (1) IL192268A0 (enExample)
PL (1) PL1963278T3 (enExample)
PT (1) PT1963278E (enExample)
RU (1) RU2427571C2 (enExample)
SI (1) SI1963278T1 (enExample)
WO (1) WO2007079927A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2257526T3 (pl) 2008-03-27 2012-05-31 Gruenenthal Gmbh Pochodne spiro (5.5) undekanu
US8357705B2 (en) 2008-03-27 2013-01-22 Gruenenthal Gmbh Substituted cyclohexyldiamines
ES2694103T3 (es) 2008-03-27 2018-12-18 Grünenthal GmbH Derivados de 4-aminociclohexano sustituidos
CL2009000731A1 (es) 2008-03-27 2009-05-15 Gruenenthal Gmbh Compuestos derivados de ciclohexano espirociclicos sustituidos, composicion farmaceutica que contiene a dicho compuesto y su uso como moduladores del receptor de opioides µ y el receptor orl-1 para tratar el dolor, ansiedad, depresion, epilepsia, alzheimer, abuso de alcohol, hipertension, anorexia, obesidad y diarrea.
JP5599774B2 (ja) 2008-03-27 2014-10-01 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ヒドロキシメチルシクロヘキシルアミン類
HUE026184T2 (en) 2008-03-27 2016-05-30 Gruenenthal Gmbh (Hetero-) aryl-cyclohexane derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9034798A (en) * 1997-08-28 1999-03-16 Eli Lilly And Company Method for treating pain
US5952360A (en) * 1997-08-28 1999-09-14 Eli Lilly And Company Method for treating neuropathic pain
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
US7183276B2 (en) * 2002-02-28 2007-02-27 Takeda Pharmaceutical Company Limited Azole compounds
US6878735B2 (en) * 2002-05-31 2005-04-12 Board Of Trustees Of Michigan State University Multi-substituted imidazolines and method of use thereof
US7345078B2 (en) * 2002-05-31 2008-03-18 The Board Of Trustees Of Michigan State University NF-κB inhibitors and uses thereof
DE102005061429A1 (de) * 2005-12-22 2007-06-28 Grünenthal GmbH Substituierte Oxazol-Derivate

Also Published As

Publication number Publication date
PT1963278E (pt) 2009-12-16
DE502006005426D1 (de) 2009-12-31
EP1963278B1 (de) 2009-11-18
US20090048323A1 (en) 2009-02-19
ATE449075T1 (de) 2009-12-15
AU2006334743A1 (en) 2007-07-19
RU2427571C2 (ru) 2011-08-27
CN101384557A (zh) 2009-03-11
US7728028B2 (en) 2010-06-01
CA2633918A1 (en) 2007-07-19
WO2007079927A1 (de) 2007-07-19
CY1110465T1 (el) 2015-04-29
AU2006334743B2 (en) 2011-07-07
HK1122019A1 (zh) 2009-05-08
EP1963278A1 (de) 2008-09-03
IL192268A0 (en) 2008-12-29
DE102005061430A1 (de) 2007-07-05
DK1963278T3 (da) 2010-03-29
JP2009523124A (ja) 2009-06-18
PL1963278T3 (pl) 2010-04-30
RU2008129377A (ru) 2010-03-27
ES2336833T3 (es) 2010-04-16

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