DK1828125T3 - Arylpiperazinderivater og deres anvendelse som selektive ligander for dopaminets D3 receptor - Google Patents
Arylpiperazinderivater og deres anvendelse som selektive ligander for dopaminets D3 receptorInfo
- Publication number
- DK1828125T3 DK1828125T3 DK05822892T DK05822892T DK1828125T3 DK 1828125 T3 DK1828125 T3 DK 1828125T3 DK 05822892 T DK05822892 T DK 05822892T DK 05822892 T DK05822892 T DK 05822892T DK 1828125 T3 DK1828125 T3 DK 1828125T3
- Authority
- DK
- Denmark
- Prior art keywords
- nrr
- alkylene
- polyfluoro
- alkyl
- dopamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0412763A FR2878524B1 (fr) | 2004-12-01 | 2004-12-01 | Nouveaux derives d'arylpiperazine |
PCT/FR2005/002964 WO2006058993A1 (fr) | 2004-12-01 | 2005-11-29 | Derives d’arylpiperazine et leur utilisation comme ligands selectifs du recepteur d3 de la dopamine |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1828125T3 true DK1828125T3 (da) | 2008-08-04 |
Family
ID=34951009
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05822892T DK1828125T3 (da) | 2004-12-01 | 2005-11-29 | Arylpiperazinderivater og deres anvendelse som selektive ligander for dopaminets D3 receptor |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080214542A1 (da) |
EP (1) | EP1828125B1 (da) |
AT (1) | ATE391711T1 (da) |
DE (1) | DE602005006018T2 (da) |
DK (1) | DK1828125T3 (da) |
ES (1) | ES2302254T3 (da) |
FR (1) | FR2878524B1 (da) |
HR (1) | HRP20080187T3 (da) |
PL (1) | PL1828125T3 (da) |
PT (1) | PT1828125E (da) |
SI (1) | SI1828125T1 (da) |
WO (1) | WO2006058993A1 (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1836192A2 (en) * | 2005-01-03 | 2007-09-26 | Universita' Degli Studi di Siena | Aryl piperazine derivatives for the treatment of neuropsychiatric disorders |
EP1870405A1 (en) * | 2006-06-22 | 2007-12-26 | Bioprojet | Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands |
WO2009095438A1 (en) * | 2008-02-01 | 2009-08-06 | Neurosearch A/S | Novel aryl piperazine derivatives useful as modulators of dopamine and serotonin receptors |
EP2257531A1 (en) * | 2008-03-14 | 2010-12-08 | NeuroSearch A/S | Novel quinolinylamide derivatives useful as modulators of dopamine and serotonin receptors |
US8829001B2 (en) | 2008-10-10 | 2014-09-09 | The Institute of Pharmacology and Toxicology Academy of Military Medical Science P.L.A. China | Dopamine D3 receptor ligands and preparation and medical uses of the same |
US9227944B2 (en) | 2008-10-10 | 2016-01-05 | Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China | Dopamine D3 receptor ligands and preparation and medical uses of the same |
WO2014079504A1 (en) * | 2012-11-22 | 2014-05-30 | Biofordrug S.R.L. | Polycyclic ligands of 5-ht7 receptor and use thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ254784A (en) * | 1992-08-06 | 1996-11-26 | Smithkline Beecham Plc | Substituted 5-phenyl pyrrole derivatives and medicaments |
US5523229A (en) * | 1994-03-22 | 1996-06-04 | Trustees Of The University Of Pennsylvania | Antibodies specific for oncofetal fibronectin |
EA005013B1 (ru) * | 1999-12-30 | 2004-10-28 | Х.Лундбекк А/С | Галогензамещённые производные 4-фенил-1-пиперазина, -пиперидина и -тетрагидропиридина |
US20050222124A1 (en) * | 2002-02-13 | 2005-10-06 | Bromidge Steven M | Benzenesulfonamide derivatives as antipsychotic agents |
US20040204422A1 (en) * | 2003-04-14 | 2004-10-14 | Abbott Gmbh & Co. Kg. | N-[(Piperazinyl)hetaryl]arylsulfonamide compounds |
-
2004
- 2004-12-01 FR FR0412763A patent/FR2878524B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-29 US US11/720,526 patent/US20080214542A1/en not_active Abandoned
- 2005-11-29 DK DK05822892T patent/DK1828125T3/da active
- 2005-11-29 WO PCT/FR2005/002964 patent/WO2006058993A1/fr active Application Filing
- 2005-11-29 SI SI200530267T patent/SI1828125T1/sl unknown
- 2005-11-29 AT AT05822892T patent/ATE391711T1/de not_active IP Right Cessation
- 2005-11-29 ES ES05822892T patent/ES2302254T3/es active Active
- 2005-11-29 DE DE602005006018T patent/DE602005006018T2/de not_active Expired - Fee Related
- 2005-11-29 PL PL05822892T patent/PL1828125T3/pl unknown
- 2005-11-29 PT PT05822892T patent/PT1828125E/pt unknown
- 2005-11-29 EP EP05822892A patent/EP1828125B1/fr active Active
-
2008
- 2008-04-23 HR HR20080187T patent/HRP20080187T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FR2878524A1 (fr) | 2006-06-02 |
EP1828125A1 (fr) | 2007-09-05 |
PL1828125T3 (pl) | 2008-09-30 |
DE602005006018T2 (de) | 2008-07-10 |
SI1828125T1 (sl) | 2008-08-31 |
WO2006058993A1 (fr) | 2006-06-08 |
ES2302254T3 (es) | 2008-07-01 |
EP1828125B1 (fr) | 2008-04-09 |
ATE391711T1 (de) | 2008-04-15 |
FR2878524B1 (fr) | 2007-01-19 |
HRP20080187T3 (en) | 2008-05-31 |
DE602005006018D1 (de) | 2008-05-21 |
US20080214542A1 (en) | 2008-09-04 |
PT1828125E (pt) | 2008-08-22 |
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