SI1797038T1 - Termodinamično stabilna oblika BAY 43-9006 tosilata - Google Patents

Termodinamično stabilna oblika BAY 43-9006 tosilata

Info

Publication number
SI1797038T1
SI1797038T1 SI200531571T SI200531571T SI1797038T1 SI 1797038 T1 SI1797038 T1 SI 1797038T1 SI 200531571 T SI200531571 T SI 200531571T SI 200531571 T SI200531571 T SI 200531571T SI 1797038 T1 SI1797038 T1 SI 1797038T1
Authority
SI
Slovenia
Prior art keywords
tosylate
bay
thermodynamically stable
stable form
thermodynamically
Prior art date
Application number
SI200531571T
Other languages
English (en)
Inventor
Alfons Grunenberg
Jana Lenz
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35482258&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1797038(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of SI1797038T1 publication Critical patent/SI1797038T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
SI200531571T 2004-09-29 2005-09-20 Termodinamično stabilna oblika BAY 43-9006 tosilata SI1797038T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04023130 2004-09-29
PCT/EP2005/010119 WO2006034797A1 (en) 2004-09-29 2005-09-20 Thermodynamically stable form of bay 43-9006 tosylate
EP05797740A EP1797038B1 (en) 2004-09-29 2005-09-20 Thermodynamically stable form of bay 43-9006 tosylate

Publications (1)

Publication Number Publication Date
SI1797038T1 true SI1797038T1 (sl) 2012-10-30

Family

ID=35482258

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531571T SI1797038T1 (sl) 2004-09-29 2005-09-20 Termodinamično stabilna oblika BAY 43-9006 tosilata

Country Status (33)

Country Link
US (1) US8877933B2 (sl)
EP (1) EP1797038B1 (sl)
JP (2) JP5215666B2 (sl)
KR (4) KR20070058537A (sl)
CN (1) CN101065360B (sl)
AR (1) AR051301A1 (sl)
AU (1) AU2005289100B2 (sl)
BR (1) BRPI0515946A (sl)
CA (1) CA2581843C (sl)
CU (1) CU20070068A7 (sl)
CY (1) CY1113598T1 (sl)
DK (1) DK1797038T3 (sl)
EC (1) ECSP077356A (sl)
ES (1) ES2387812T3 (sl)
GT (1) GT200500270A (sl)
HK (1) HK1114605A1 (sl)
HN (1) HN2005000722A (sl)
HR (1) HRP20120662T1 (sl)
IL (1) IL181734A (sl)
MA (1) MA28880B1 (sl)
MY (1) MY176929A (sl)
NO (1) NO344272B1 (sl)
NZ (1) NZ553804A (sl)
PE (3) PE20060699A1 (sl)
PL (1) PL1797038T3 (sl)
PT (1) PT1797038E (sl)
SG (1) SG155996A1 (sl)
SI (1) SI1797038T1 (sl)
TW (1) TWI382016B (sl)
UA (1) UA91520C2 (sl)
UY (1) UY29144A1 (sl)
WO (1) WO2006034797A1 (sl)
ZA (1) ZA200702510B (sl)

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CN103896833B (zh) * 2012-12-27 2016-12-28 上海创诺制药有限公司 索拉非尼对甲苯磺酸盐溶剂化物多晶型物及其制法和用途
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CN110204483B (zh) * 2014-12-01 2021-06-29 石药集团中奇制药技术（石家庄）有限公司 一种甲苯磺酸索拉非尼新晶型及其制备方法
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CN105503715A (zh) * 2015-12-03 2016-04-20 神威药业集团有限公司 一种索拉非尼半甲苯磺酸盐多晶型及其制备方法
CN105585523A (zh) * 2015-12-29 2016-05-18 上海北卡医药技术有限公司 一种对甲苯磺酸索拉非尼的新晶型及其制备方法和用途
CN107759517A (zh) * 2016-08-23 2018-03-06 广州白云山医药集团股份有限公司白云山制药总厂 一种甲苯磺酸索拉非尼晶型ⅰ的制备方法
CN107840823B (zh) * 2016-09-20 2021-08-17 意大利合成制造有限公司 用于制备甲苯磺酸索拉非尼乙醇溶剂化物和iii型甲苯磺酸索拉非尼的可变规模的方法
CN108164459B (zh) * 2016-12-07 2021-07-27 上海创诺制药有限公司 甲苯磺酸索拉非尼晶型iii的制备方法
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JP2013531067A (ja) 2010-07-19 2013-08-01 バイエル ヘルスケア リミティド ライアビリティ カンパニー 疾病及び状態の処置及び予防のためのフルオロ置換オメガ−カルボキシアリールジフェニル尿素を用いた組み合わせ薬
CN103228274A (zh) 2010-10-01 2013-07-31 拜耳知识产权有限责任公司 包含取代的n-(2-芳基氨基)芳基磺酰胺的组合
US20140296301A1 (en) 2011-06-28 2014-10-02 Bayer Pharma Aktiengesellschaft Topical ophthalmological pharmaceutical composition containing regoragenib
WO2013000909A1 (en) 2011-06-28 2013-01-03 Bayer Intellectual Property Gmbh Topical ophthalmological pharmaceutical composition containing sorafenib

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