SI1383770T1 - Postopek za proizvodnjo 4,6-diaminopirimido(5,4-d)-pirimidinov - Google Patents
Postopek za proizvodnjo 4,6-diaminopirimido(5,4-d)-pirimidinovInfo
- Publication number
- SI1383770T1 SI1383770T1 SI200230048T SI200230048T SI1383770T1 SI 1383770 T1 SI1383770 T1 SI 1383770T1 SI 200230048 T SI200230048 T SI 200230048T SI 200230048 T SI200230048 T SI 200230048T SI 1383770 T1 SI1383770 T1 SI 1383770T1
- Authority
- SI
- Slovenia
- Prior art keywords
- diaminopyrimido
- pyrimidines
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10115921A DE10115921A1 (de) | 2001-03-30 | 2001-03-30 | Verfahren zur Herstellung von 4,6-Diaminopyrimido[5,4-d]pyrimidinen |
| EP02757725A EP1383770B1 (de) | 2001-03-30 | 2002-03-26 | Verfahren zur herstellung von 4,6-diaminopyrimido 5,4-d]pyrimidinen |
| PCT/EP2002/003353 WO2002079202A1 (de) | 2001-03-30 | 2002-03-26 | Verfahren zur herstellung von 4,6-diaminopyrimido[5,4-d]pyrimidinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1383770T1 true SI1383770T1 (sl) | 2005-02-28 |
Family
ID=7679773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230048T SI1383770T1 (sl) | 2001-03-30 | 2002-03-26 | Postopek za proizvodnjo 4,6-diaminopirimido(5,4-d)-pirimidinov |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6680384B2 (cs) |
| EP (1) | EP1383770B1 (cs) |
| JP (1) | JP4451066B2 (cs) |
| KR (1) | KR20030086338A (cs) |
| CN (1) | CN1252072C (cs) |
| AT (1) | ATE277052T1 (cs) |
| BR (1) | BR0208534A (cs) |
| CA (1) | CA2442061C (cs) |
| CZ (1) | CZ296237B6 (cs) |
| DE (2) | DE10115921A1 (cs) |
| DK (1) | DK1383770T3 (cs) |
| ES (1) | ES2224073T3 (cs) |
| HR (1) | HRP20030781A2 (cs) |
| HU (1) | HUP0303590A3 (cs) |
| MX (1) | MXPA03008811A (cs) |
| PL (1) | PL362922A1 (cs) |
| PT (1) | PT1383770E (cs) |
| SI (1) | SI1383770T1 (cs) |
| SK (1) | SK11982003A3 (cs) |
| TR (1) | TR200402474T4 (cs) |
| WO (1) | WO2002079202A1 (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040242568A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| EP1625122A1 (en) | 2003-05-14 | 2006-02-15 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7579357B2 (en) | 2003-08-13 | 2009-08-25 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7790734B2 (en) | 2003-09-08 | 2010-09-07 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| AU2004318013B8 (en) | 2004-03-15 | 2011-10-06 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| JP2008501714A (ja) | 2004-06-04 | 2008-01-24 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼインヒビター |
| WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| EP1828192B1 (en) | 2004-12-21 | 2014-12-03 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| WO2008033851A2 (en) * | 2006-09-13 | 2008-03-20 | Takeda Pharmaceutical Company Limited | Use of 2-6- (3-amino-piperidin-l-yl) -3-methyl-2, 4-dioxo-3, 4-dihydr0-2h-pyrimidin-1-ylmet hyl-4-fluoro-benzonitrile |
| WO2007033265A1 (en) * | 2005-09-14 | 2007-03-22 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors for treating diabetis |
| JP5027137B2 (ja) | 2005-09-14 | 2012-09-19 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼ阻害剤の投与 |
| CN101360723A (zh) | 2005-09-16 | 2009-02-04 | 武田药品工业株式会社 | 制备嘧啶二酮衍生物的方法 |
| WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| KR20230170039A (ko) | 2021-04-13 | 2023-12-18 | 뉴베일런트, 아이엔씨. | Egfr 돌연변이를 지니는 암을 치료하기 위한 아미노-치환된 헤테로사이클 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW414798B (en) | 1994-09-07 | 2000-12-11 | Thomae Gmbh Dr K | Pyrimido (5,4-d) pyrimidines, medicaments comprising these compounds, their use and processes for their preparation |
| DE19608588A1 (de) | 1996-03-06 | 1997-09-11 | Thomae Gmbh Dr K | Pyrimido [5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
-
2001
- 2001-03-30 DE DE10115921A patent/DE10115921A1/de not_active Withdrawn
-
2002
- 2002-03-12 US US10/095,926 patent/US6680384B2/en not_active Expired - Lifetime
- 2002-03-26 SI SI200230048T patent/SI1383770T1/xx unknown
- 2002-03-26 CA CA2442061A patent/CA2442061C/en not_active Expired - Fee Related
- 2002-03-26 HR HR20030781A patent/HRP20030781A2/hr not_active Application Discontinuation
- 2002-03-26 EP EP02757725A patent/EP1383770B1/de not_active Expired - Lifetime
- 2002-03-26 AT AT02757725T patent/ATE277052T1/de active
- 2002-03-26 PL PL02362922A patent/PL362922A1/xx not_active Application Discontinuation
- 2002-03-26 MX MXPA03008811A patent/MXPA03008811A/es active IP Right Grant
- 2002-03-26 WO PCT/EP2002/003353 patent/WO2002079202A1/de active IP Right Grant
- 2002-03-26 CN CNB028075994A patent/CN1252072C/zh not_active Expired - Fee Related
- 2002-03-26 BR BR0208534-8A patent/BR0208534A/pt not_active IP Right Cessation
- 2002-03-26 SK SK1198-2003A patent/SK11982003A3/sk unknown
- 2002-03-26 KR KR10-2003-7012853A patent/KR20030086338A/ko not_active Ceased
- 2002-03-26 TR TR2004/02474T patent/TR200402474T4/xx unknown
- 2002-03-26 DK DK02757725T patent/DK1383770T3/da active
- 2002-03-26 CZ CZ20032654A patent/CZ296237B6/cs not_active IP Right Cessation
- 2002-03-26 DE DE50201120T patent/DE50201120D1/de not_active Expired - Lifetime
- 2002-03-26 PT PT02757725T patent/PT1383770E/pt unknown
- 2002-03-26 ES ES02757725T patent/ES2224073T3/es not_active Expired - Lifetime
- 2002-03-26 HU HU0303590A patent/HUP0303590A3/hu unknown
- 2002-03-26 JP JP2002577826A patent/JP4451066B2/ja not_active Expired - Fee Related
-
2003
- 2003-09-25 US US10/670,535 patent/US6849734B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1383770T3 (da) | 2004-12-20 |
| EP1383770B1 (de) | 2004-09-22 |
| HUP0303590A2 (hu) | 2004-03-01 |
| DE50201120D1 (de) | 2004-10-28 |
| CZ20032654A3 (cs) | 2004-02-18 |
| EP1383770A1 (de) | 2004-01-28 |
| ATE277052T1 (de) | 2004-10-15 |
| US6680384B2 (en) | 2004-01-20 |
| CA2442061C (en) | 2010-06-29 |
| CN1252072C (zh) | 2006-04-19 |
| DE10115921A1 (de) | 2002-10-02 |
| PL362922A1 (en) | 2004-11-02 |
| CA2442061A1 (en) | 2002-10-10 |
| CN1500091A (zh) | 2004-05-26 |
| PT1383770E (pt) | 2004-11-30 |
| HK1064091A1 (en) | 2005-01-21 |
| JP2004525944A (ja) | 2004-08-26 |
| US6849734B2 (en) | 2005-02-01 |
| US20040059114A1 (en) | 2004-03-25 |
| TR200402474T4 (tr) | 2004-12-21 |
| KR20030086338A (ko) | 2003-11-07 |
| HUP0303590A3 (en) | 2004-11-29 |
| ES2224073T3 (es) | 2005-03-01 |
| MXPA03008811A (es) | 2004-02-18 |
| BR0208534A (pt) | 2004-03-23 |
| SK11982003A3 (sk) | 2004-02-03 |
| WO2002079202A1 (de) | 2002-10-10 |
| US20020198380A1 (en) | 2002-12-26 |
| CZ296237B6 (cs) | 2006-02-15 |
| JP4451066B2 (ja) | 2010-04-14 |
| HRP20030781A2 (en) | 2005-06-30 |
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