SI1147121T1 - Ketolidni antibiotiki - Google Patents

Ketolidni antibiotiki

Info

Publication number
SI1147121T1
SI1147121T1 SI9930486T SI9930486T SI1147121T1 SI 1147121 T1 SI1147121 T1 SI 1147121T1 SI 9930486 T SI9930486 T SI 9930486T SI 9930486 T SI9930486 T SI 9930486T SI 1147121 T1 SI1147121 T1 SI 1147121T1
Authority
SI
Slovenia
Prior art keywords
ketolide antibiotics
ketolide
antibiotics
Prior art date
Application number
SI9930486T
Other languages
English (en)
Inventor
Takushi Kaneko
William Thomas Mcmillen
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of SI1147121T1 publication Critical patent/SI1147121T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
SI9930486T 1999-01-27 1999-12-28 Ketolidni antibiotiki SI1147121T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11734299P 1999-01-27 1999-01-27
PCT/IB1999/002051 WO2000044761A2 (en) 1999-01-27 1999-12-28 Ketolide antibiotics
EP99959627A EP1147121B1 (en) 1999-01-27 1999-12-28 Ketolide antibiotics

Publications (1)

Publication Number Publication Date
SI1147121T1 true SI1147121T1 (sl) 2004-04-30

Family

ID=22372371

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930486T SI1147121T1 (sl) 1999-01-27 1999-12-28 Ketolidni antibiotiki

Country Status (39)

Country Link
US (1) US6833444B2 (sl)
EP (1) EP1147121B1 (sl)
JP (1) JP3947360B2 (sl)
KR (1) KR20020002380A (sl)
CN (1) CN1342163A (sl)
AP (1) AP2001002222A0 (sl)
AT (1) ATE256694T1 (sl)
AU (1) AU1675400A (sl)
BG (1) BG105730A (sl)
BR (1) BR9916969A (sl)
CA (1) CA2359708C (sl)
CO (1) CO5150229A1 (sl)
CZ (1) CZ20012675A3 (sl)
DE (1) DE69913738T2 (sl)
DK (1) DK1147121T3 (sl)
DZ (1) DZ3000A1 (sl)
EA (1) EA200100623A1 (sl)
EE (1) EE200100394A (sl)
ES (1) ES2212655T3 (sl)
HK (1) HK1042707A1 (sl)
HN (1) HN2000000003A (sl)
HR (1) HRP20010559A2 (sl)
HU (1) HUP0105190A3 (sl)
ID (1) ID30233A (sl)
IL (1) IL144178A0 (sl)
IS (1) IS5984A (sl)
MA (1) MA26717A1 (sl)
NO (1) NO20013680L (sl)
OA (1) OA11753A (sl)
PA (1) PA8489501A1 (sl)
PE (1) PE20001422A1 (sl)
PT (1) PT1147121E (sl)
SI (1) SI1147121T1 (sl)
SK (1) SK10172001A3 (sl)
TN (1) TNSN00007A1 (sl)
TR (1) TR200102128T2 (sl)
UY (1) UY25990A1 (sl)
WO (1) WO2000044761A2 (sl)
ZA (1) ZA200105580B (sl)

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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
OA11753A (en) 1999-01-27 2005-07-19 Pfizer Prod Inc Ketolide antibiotics.
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
CN1373767A (zh) 1999-04-16 2002-10-09 奥索-麦克尼尔药品公司 酮式大环内酯抗菌剂
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
JP2003523938A (ja) 1999-04-16 2003-08-12 コーサン バイオサイエンシーズ, インコーポレイテッド マクロライド系抗感染剤
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
TR200401847T4 (tr) 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
AU2002217277B2 (en) * 2000-12-21 2005-06-16 Glaxo Group Limited Macrolide antibiotics
PE20030438A1 (es) * 2001-09-05 2003-07-03 Hokuriku Pharmaceutical Medicamento que comprende un derivado de eritromicina como agente antituberculoso
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
EP1794171A2 (en) * 2004-07-28 2007-06-13 Ranbaxy Laboratories, Ltd. Ketolide derivatives as antibacterial agents
EP1836211B1 (en) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
WO2007129646A1 (ja) * 2006-05-01 2007-11-15 Taisho Pharmaceutical Co., Ltd. マクロライド誘導体
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308180B2 (en) 2008-10-24 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating gastrointestinal diseases
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
ES2564097T3 (es) 2010-03-22 2016-03-17 Cempra Pharmaceuticals, Inc. Formas cristalinas de un macrólido, y usos de las mismas
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
JP6208742B2 (ja) 2012-03-27 2017-10-04 センプラ ファーマシューティカルズ,インコーポレイテッド マクロライド抗生物質を投与するための非経口製剤
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
JP6332266B2 (ja) 2013-03-28 2018-05-30 不二製油株式会社 緑豆蛋白ゲル状組成物及びチーズ様食品
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
CN110234323A (zh) * 2016-10-04 2019-09-13 Ti生物制药有限公司 具有抗菌活性的酮内酯

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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
EP1115732B1 (en) 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PL348114A1 (en) 1998-11-03 2002-05-06 Pfizer Prod Inc Novel macrolide antibiotics
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
ATE344269T1 (de) * 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
OA11753A (en) 1999-01-27 2005-07-19 Pfizer Prod Inc Ketolide antibiotics.
FR2789392B1 (fr) 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP2003523938A (ja) 1999-04-16 2003-08-12 コーサン バイオサイエンシーズ, インコーポレイテッド マクロライド系抗感染剤
CN1373767A (zh) 1999-04-16 2002-10-09 奥索-麦克尼尔药品公司 酮式大环内酯抗菌剂
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
TR200401847T4 (tr) 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.

Also Published As

Publication number Publication date
CA2359708C (en) 2005-10-25
EP1147121B1 (en) 2003-12-17
WO2000044761A2 (en) 2000-08-03
NO20013680D0 (no) 2001-07-26
HUP0105190A3 (en) 2003-03-28
HK1042707A1 (zh) 2002-08-23
JP2002535414A (ja) 2002-10-22
DE69913738D1 (de) 2004-01-29
CN1342163A (zh) 2002-03-27
PE20001422A1 (es) 2000-12-18
WO2000044761A3 (en) 2001-01-04
HUP0105190A2 (hu) 2002-04-29
TR200102128T2 (tr) 2001-12-21
TNSN00007A1 (fr) 2005-11-10
CA2359708A1 (en) 2000-08-03
NO20013680L (no) 2001-09-19
PT1147121E (pt) 2004-04-30
SK10172001A3 (sk) 2002-06-04
OA11753A (en) 2005-07-19
DZ3000A1 (fr) 2004-03-27
EA200100623A1 (ru) 2002-02-28
CO5150229A1 (es) 2002-04-29
HN2000000003A (es) 2001-02-02
ID30233A (id) 2001-11-15
AU1675400A (en) 2000-08-18
UY25990A1 (es) 2000-09-29
US20020156027A1 (en) 2002-10-24
DE69913738T2 (de) 2004-06-17
ZA200105580B (en) 2003-02-17
KR20020002380A (ko) 2002-01-09
IS5984A (is) 2001-06-28
EE200100394A (et) 2002-10-15
PA8489501A1 (es) 2000-09-29
JP3947360B2 (ja) 2007-07-18
IL144178A0 (en) 2002-05-23
EP1147121A2 (en) 2001-10-24
BR9916969A (pt) 2001-11-06
ES2212655T3 (es) 2004-07-16
MA26717A1 (fr) 2004-12-20
BG105730A (en) 2002-03-29
AP2001002222A0 (en) 2001-09-30
CZ20012675A3 (cs) 2002-04-17
HRP20010559A2 (en) 2002-08-31
US6833444B2 (en) 2004-12-21
DK1147121T3 (da) 2004-04-13
ATE256694T1 (de) 2004-01-15

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