SI0950049T1 - Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them - Google Patents

Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them

Info

Publication number
SI0950049T1
SI0950049T1 SI9730241T SI9730241T SI0950049T1 SI 0950049 T1 SI0950049 T1 SI 0950049T1 SI 9730241 T SI9730241 T SI 9730241T SI 9730241 T SI9730241 T SI 9730241T SI 0950049 T1 SI0950049 T1 SI 0950049T1
Authority
SI
Slovenia
Prior art keywords
pct
preparation
pharmaceutical compositions
compositions containing
tetrahydropyridines
Prior art date
Application number
SI9730241T
Other languages
English (en)
Slovenian (sl)
Inventor
Marco Baroni
Rosanna Cardamone
Jacqueline Fournier
Umberto Guzzi
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of SI0950049T1 publication Critical patent/SI0950049T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9730241T 1996-12-13 1997-12-12 Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them SI0950049T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9615336A FR2757161B1 (fr) 1996-12-13 1996-12-13 Diphenylalkyl-tetrahydropyridines
EP97951326A EP0950049B1 (fr) 1996-12-13 1997-12-12 Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant
PCT/FR1997/002289 WO1998025904A1 (fr) 1996-12-13 1997-12-12 Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant

Publications (1)

Publication Number Publication Date
SI0950049T1 true SI0950049T1 (en) 2002-10-31

Family

ID=9498642

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730241T SI0950049T1 (en) 1996-12-13 1997-12-12 Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (1) US6124318A (ko)
EP (1) EP0950049B1 (ko)
JP (1) JP2001505903A (ko)
KR (1) KR100549656B1 (ko)
CN (1) CN1144784C (ko)
AT (1) ATE207056T1 (ko)
AU (1) AU730142B2 (ko)
BR (1) BR9713926A (ko)
CA (1) CA2274946C (ko)
CY (1) CY2282B1 (ko)
CZ (1) CZ290242B6 (ko)
DE (1) DE69707504T2 (ko)
DK (1) DK0950049T3 (ko)
EE (1) EE03764B1 (ko)
ES (1) ES2167805T3 (ko)
FR (1) FR2757161B1 (ko)
HK (1) HK1024001A1 (ko)
HU (1) HUP0001437A3 (ko)
IL (2) IL130001A0 (ko)
IS (1) IS2001B (ko)
NO (1) NO313282B1 (ko)
NZ (1) NZ336032A (ko)
PL (1) PL192926B1 (ko)
PT (1) PT950049E (ko)
RS (1) RS49672B (ko)
RU (1) RU2198874C2 (ko)
SI (1) SI0950049T1 (ko)
SK (1) SK283332B6 (ko)
TR (1) TR199901290T2 (ko)
UA (1) UA52708C2 (ko)
WO (1) WO1998025904A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
JP2003530432A (ja) * 2000-04-12 2003-10-14 ミナーヴァ・バイオテクノロジーズ・コーポレーション 神経変性疾患の治療
AU2002314744A1 (en) 2001-04-17 2002-10-28 Sepracor, Inc. Thiazole and other heterocyclic ligands and use thereof
WO2005065661A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galanthamine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
BE775611A (fr) * 1970-11-24 1972-03-16 Synthelabo Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent
US5266573A (en) * 1989-08-07 1993-11-30 Elf Sanofi Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5512584A (en) * 1991-04-16 1996-04-30 Basf Aktiengesellschaft 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser

Also Published As

Publication number Publication date
TR199901290T2 (xx) 1999-08-23
HUP0001437A3 (en) 2001-12-28
CY2282B1 (en) 2003-07-04
CN1240428A (zh) 2000-01-05
UA52708C2 (uk) 2003-01-15
IS5074A (is) 1999-06-10
DE69707504D1 (de) 2001-11-22
WO1998025904A1 (fr) 1998-06-18
IS2001B (is) 2005-04-15
RU2198874C2 (ru) 2003-02-20
NO992870L (no) 1999-08-11
YU26399A (sh) 2000-03-21
ATE207056T1 (de) 2001-11-15
AU5489598A (en) 1998-07-03
ES2167805T3 (es) 2002-05-16
NO313282B1 (no) 2002-09-09
FR2757161A1 (fr) 1998-06-19
DK0950049T3 (da) 2002-01-28
US6124318A (en) 2000-09-26
PL192926B1 (pl) 2006-12-29
NZ336032A (en) 2000-12-22
IL130001A (en) 2006-04-10
EP0950049A1 (fr) 1999-10-20
RS49672B (sr) 2007-11-15
SK78799A3 (en) 1999-12-10
EP0950049B1 (fr) 2001-10-17
CA2274946C (en) 2005-09-20
CN1144784C (zh) 2004-04-07
NO992870D0 (no) 1999-06-11
AU730142B2 (en) 2001-03-01
JP2001505903A (ja) 2001-05-08
CA2274946A1 (en) 1998-06-18
CZ211099A3 (cs) 1999-09-15
SK283332B6 (sk) 2003-06-03
HUP0001437A2 (hu) 2000-09-28
EE03764B1 (et) 2002-06-17
BR9713926A (pt) 2000-03-21
PL334073A1 (en) 2000-01-31
DE69707504T2 (de) 2002-06-27
CZ290242B6 (cs) 2002-06-12
HK1024001A1 (en) 2000-09-29
PT950049E (pt) 2002-03-28
IL130001A0 (en) 2000-02-29
KR20000069421A (ko) 2000-11-25
KR100549656B1 (ko) 2006-02-08
EE9900238A (et) 1999-12-15
FR2757161B1 (fr) 1999-03-12

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