SI0868428T1 - Phosphonic acid derivatives with metallopeptidase inhibitory activity - Google Patents

Phosphonic acid derivatives with metallopeptidase inhibitory activity

Info

Publication number
SI0868428T1
SI0868428T1 SI9630584T SI9630584T SI0868428T1 SI 0868428 T1 SI0868428 T1 SI 0868428T1 SI 9630584 T SI9630584 T SI 9630584T SI 9630584 T SI9630584 T SI 9630584T SI 0868428 T1 SI0868428 T1 SI 0868428T1
Authority
SI
Slovenia
Prior art keywords
aryl
heterocycle
inhibitory activity
acid derivatives
phosphonic acid
Prior art date
Application number
SI9630584T
Other languages
English (en)
Slovenian (sl)
Inventor
Gabriele Norcini
Daniela Botta
Francesco Santangelo
Original Assignee
Zambon Group S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group S.P.A. filed Critical Zambon Group S.P.A.
Publication of SI0868428T1 publication Critical patent/SI0868428T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
SI9630584T 1995-11-23 1996-11-11 Phosphonic acid derivatives with metallopeptidase inhibitory activity SI0868428T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT95MI002430A IT1276161B1 (it) 1995-11-23 1995-11-23 Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
PCT/EP1996/004911 WO1997019102A1 (en) 1995-11-23 1996-11-11 Phosphonic acid derivatives with metallopeptidase inhibitory activity
EP96938164A EP0868428B1 (en) 1995-11-23 1996-11-11 Phosphonic acid derivatives with metallopeptidase inhibitory activity

Publications (1)

Publication Number Publication Date
SI0868428T1 true SI0868428T1 (en) 2003-06-30

Family

ID=11372578

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630584T SI0868428T1 (en) 1995-11-23 1996-11-11 Phosphonic acid derivatives with metallopeptidase inhibitory activity

Country Status (23)

Country Link
US (1) US6548480B1 (xx)
EP (1) EP0868428B1 (xx)
JP (1) JP2000501079A (xx)
KR (1) KR100458359B1 (xx)
CN (1) CN1127513C (xx)
AT (1) ATE234856T1 (xx)
AU (1) AU707570B2 (xx)
BR (1) BR9611465A (xx)
CA (1) CA2249343A1 (xx)
CZ (1) CZ291926B6 (xx)
DE (1) DE69626846T2 (xx)
DK (1) DK0868428T3 (xx)
EA (1) EA000743B1 (xx)
ES (1) ES2192619T3 (xx)
HU (1) HUP0000080A3 (xx)
IL (1) IL124021A (xx)
IT (1) IT1276161B1 (xx)
MX (1) MX9803760A (xx)
NO (1) NO982363L (xx)
PT (1) PT868428E (xx)
SI (1) SI0868428T1 (xx)
WO (1) WO1997019102A1 (xx)
ZA (1) ZA969774B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3973748B2 (ja) 1998-01-14 2007-09-12 花王株式会社 発毛抑制剤
JP4796296B2 (ja) * 2004-12-02 2011-10-19 インターナショナル・ビジネス・マシーンズ・コーポレーション Ｗｅｂページ・オーサリング装置、Ｗｅｂページ・オーサリング方法及びプログラム
CN101636527B (zh) * 2007-03-15 2011-11-09 日矿金属株式会社 铜电解液和使用该铜电解液得到的两层挠性基板

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1276392C (en) * 1981-08-03 1990-11-13 Donald S. Karanewsky Phosphonamidate compounds
US4432972A (en) * 1981-08-03 1984-02-21 E. R. Squibb & Sons, Inc. Phosphonamidate compounds
IT1274673B (it) * 1994-04-14 1997-07-24 Zambon Spa Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari

Also Published As

Publication number Publication date
WO1997019102A1 (en) 1997-05-29
NO982363D0 (no) 1998-05-25
DK0868428T3 (da) 2003-07-21
ES2192619T3 (es) 2003-10-16
CN1127513C (zh) 2003-11-12
NO982363L (no) 1998-07-22
ITMI952430A1 (it) 1997-05-23
EP0868428B1 (en) 2003-03-19
EA199800470A1 (ru) 1998-12-24
PT868428E (pt) 2003-06-30
HUP0000080A3 (en) 2001-05-28
ATE234856T1 (de) 2003-04-15
HUP0000080A2 (hu) 2001-04-28
MX9803760A (es) 1998-09-30
AU707570B2 (en) 1999-07-15
KR100458359B1 (ko) 2005-01-15
AU7568996A (en) 1997-06-11
IT1276161B1 (it) 1997-10-27
CZ291926B6 (cs) 2003-06-18
KR19990071550A (ko) 1999-09-27
DE69626846T2 (de) 2003-12-24
CN1202901A (zh) 1998-12-23
EA000743B1 (ru) 2000-02-28
ITMI952430A0 (xx) 1995-11-23
CZ158898A3 (cs) 1998-11-11
IL124021A (en) 2001-06-14
CA2249343A1 (en) 1997-05-29
DE69626846D1 (de) 2003-04-24
ZA969774B (en) 1997-06-17
US6548480B1 (en) 2003-04-15
BR9611465A (pt) 1999-05-18
EP0868428A1 (en) 1998-10-07
JP2000501079A (ja) 2000-02-02

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