ATE234856T1 - Phosphonsäurederivate mit metallopeptidase inhibierender aktivität - Google Patents

Phosphonsäurederivate mit metallopeptidase inhibierender aktivität

Info

Publication number
ATE234856T1
ATE234856T1 AT96938164T AT96938164T ATE234856T1 AT E234856 T1 ATE234856 T1 AT E234856T1 AT 96938164 T AT96938164 T AT 96938164T AT 96938164 T AT96938164 T AT 96938164T AT E234856 T1 ATE234856 T1 AT E234856T1
Authority
AT
Austria
Prior art keywords
aryl
heterocycle
metallopeptidase
acid derivatives
phosphonic acid
Prior art date
Application number
AT96938164T
Other languages
English (en)
Inventor
Gabriele Norcini
Daniela Botta
Francesco Santangelo
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of ATE234856T1 publication Critical patent/ATE234856T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
AT96938164T 1995-11-23 1996-11-11 Phosphonsäurederivate mit metallopeptidase inhibierender aktivität ATE234856T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI002430A IT1276161B1 (it) 1995-11-23 1995-11-23 Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
PCT/EP1996/004911 WO1997019102A1 (en) 1995-11-23 1996-11-11 Phosphonic acid derivatives with metallopeptidase inhibitory activity

Publications (1)

Publication Number Publication Date
ATE234856T1 true ATE234856T1 (de) 2003-04-15

Family

ID=11372578

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938164T ATE234856T1 (de) 1995-11-23 1996-11-11 Phosphonsäurederivate mit metallopeptidase inhibierender aktivität

Country Status (23)

Country Link
US (1) US6548480B1 (de)
EP (1) EP0868428B1 (de)
JP (1) JP2000501079A (de)
KR (1) KR100458359B1 (de)
CN (1) CN1127513C (de)
AT (1) ATE234856T1 (de)
AU (1) AU707570B2 (de)
BR (1) BR9611465A (de)
CA (1) CA2249343A1 (de)
CZ (1) CZ291926B6 (de)
DE (1) DE69626846T2 (de)
DK (1) DK0868428T3 (de)
EA (1) EA000743B1 (de)
ES (1) ES2192619T3 (de)
HU (1) HUP0000080A3 (de)
IL (1) IL124021A (de)
IT (1) IT1276161B1 (de)
MX (1) MX9803760A (de)
NO (1) NO982363L (de)
PT (1) PT868428E (de)
SI (1) SI0868428T1 (de)
WO (1) WO1997019102A1 (de)
ZA (1) ZA969774B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3973748B2 (ja) 1998-01-14 2007-09-12 花王株式会社 発毛抑制剤
JP4796296B2 (ja) * 2004-12-02 2011-10-19 インターナショナル・ビジネス・マシーンズ・コーポレーション Ｗｅｂページ・オーサリング装置、Ｗｅｂページ・オーサリング方法及びプログラム
JPWO2008126522A1 (ja) * 2007-03-15 2010-07-22 日鉱金属株式会社 銅電解液及びそれを用いて得られた２層フレキシブル基板

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4432972A (en) * 1981-08-03 1984-02-21 E. R. Squibb & Sons, Inc. Phosphonamidate compounds
EP0071544B1 (de) * 1981-08-03 1986-10-08 E.R. Squibb & Sons, Inc. Phosphonamidate Verbindungen
IT1274673B (it) * 1994-04-14 1997-07-24 Zambon Spa Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari

Also Published As

Publication number Publication date
DE69626846T2 (de) 2003-12-24
AU7568996A (en) 1997-06-11
MX9803760A (es) 1998-09-30
KR100458359B1 (ko) 2005-01-15
AU707570B2 (en) 1999-07-15
EP0868428A1 (de) 1998-10-07
ZA969774B (en) 1997-06-17
WO1997019102A1 (en) 1997-05-29
CA2249343A1 (en) 1997-05-29
SI0868428T1 (en) 2003-06-30
CN1127513C (zh) 2003-11-12
IL124021A (en) 2001-06-14
US6548480B1 (en) 2003-04-15
KR19990071550A (ko) 1999-09-27
EA199800470A1 (ru) 1998-12-24
CZ291926B6 (cs) 2003-06-18
EA000743B1 (ru) 2000-02-28
HUP0000080A2 (hu) 2001-04-28
EP0868428B1 (de) 2003-03-19
PT868428E (pt) 2003-06-30
DE69626846D1 (de) 2003-04-24
DK0868428T3 (da) 2003-07-21
NO982363L (no) 1998-07-22
HUP0000080A3 (en) 2001-05-28
CN1202901A (zh) 1998-12-23
CZ158898A3 (cs) 1998-11-11
ITMI952430A1 (it) 1997-05-23
JP2000501079A (ja) 2000-02-02
BR9611465A (pt) 1999-05-18
ITMI952430A0 (de) 1995-11-23
ES2192619T3 (es) 2003-10-16
IT1276161B1 (it) 1997-10-27
NO982363D0 (no) 1998-05-25

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