SG99880A1 - A method of chromatographic isolation for vitamin e isomers - Google Patents

A method of chromatographic isolation for vitamin e isomers

Info

Publication number
SG99880A1
SG99880A1 SG200100434A SG200100434A SG99880A1 SG 99880 A1 SG99880 A1 SG 99880A1 SG 200100434 A SG200100434 A SG 200100434A SG 200100434 A SG200100434 A SG 200100434A SG 99880 A1 SG99880 A1 SG 99880A1
Authority
SG
Singapore
Prior art keywords
isomers
vitamin
chromatographic isolation
chromatographic
isolation
Prior art date
Application number
SG200100434A
Other languages
English (en)
Inventor
Choo Yuen May Dr
Ma Ah Ngan Dr
Dr Yusof Basiron Datuk
Original Assignee
Malaysian Palm Oil Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Malaysian Palm Oil Board filed Critical Malaysian Palm Oil Board
Publication of SG99880A1 publication Critical patent/SG99880A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/265—Adsorption chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG200100434A 2000-02-02 2001-02-01 A method of chromatographic isolation for vitamin e isomers SG99880A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI20000368A MY127451A (en) 1999-11-04 2000-02-02 A method of chromatographic isolation for vitamin e isomers

Publications (1)

Publication Number Publication Date
SG99880A1 true SG99880A1 (en) 2003-11-27

Family

ID=19749442

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200100434A SG99880A1 (en) 2000-02-02 2001-02-01 A method of chromatographic isolation for vitamin e isomers

Country Status (8)

Country Link
US (1) US6656358B2 (de)
EP (1) EP1122250B1 (de)
JP (2) JP5051943B2 (de)
AU (1) AU783564B2 (de)
CA (1) CA2334068C (de)
DE (1) DE60103431T2 (de)
MY (1) MY127451A (de)
SG (1) SG99880A1 (de)

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MY127451A (en) 1999-11-04 2006-12-29 Malaysian Palm Oil Board A method of chromatographic isolation for vitamin e isomers
MY127954A (en) 1999-11-04 2007-01-31 Malaysian Palm Oil Board A method of chromatographic isolation for non-glyceride components
MY130618A (en) * 2002-11-27 2007-07-31 Malaysian Palm Oil Board A method of extracting and isolating minor components from vegetable oil
MY138963A (en) * 2003-08-27 2009-08-28 Malaysian Palm Oil Board One-stage and two-stage supercritical fluid extractions of carotenes concentrate, vitamin e concentrate and other minor components concentrates
MY146635A (en) * 2004-09-01 2012-09-14 Malaysian Palm Oil Board Specialty palm oil products and other specialty vegetable oil products
US7332159B2 (en) * 2004-09-30 2008-02-19 Board Of Regents Of The University Of Nebraska Method and composition for inhibiting reperfusion injury in the brain
DK1888059T3 (en) 2005-06-01 2015-03-30 Edison Pharmaceuticals Inc Redox-active therapeutic products for the treatment of mitochondrial diseases and other conditions as well as modulation of energy biomarkers
JP4943001B2 (ja) * 2005-12-27 2012-05-30 ライオン株式会社 トコトリエノール類含有組成物の製造方法
ES2345396T3 (es) * 2006-02-10 2010-09-22 Carotech Sdn. Bhd Proceso para la produccion de fracciones altamente enriquecidas de compuestos naturales de aceite de palma con fluidos supercriticos y proximos al estado critico.
EP1986636B1 (de) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien
MY148321A (en) * 2007-10-02 2013-03-29 Malaysian Palm Oil Board Mpob Vitamin e supplementation to tetanus toxoid
DE102007061436A1 (de) * 2007-12-20 2009-06-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Gewinnung von Fettbegleitstoffen aus Kraftstoffen und Verwendung dieses Verfahrens
EP2344142B1 (de) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Behandlung von pervasiven entwicklungsstörungen mit redox-aktiven therapeutika
CA2974482C (en) 2008-10-28 2019-10-29 Bioelectron Technology Corporation High purity alpha tocotrienol quinone and processes for preparing same
BRPI1013376A8 (pt) 2009-04-28 2017-07-11 Edison Pharmaceuticals Inc Uso de quinonas de tocotrienol,preparação farmacêutica compreendendo as ditas quinonas e uso desta
US20120122969A1 (en) 2009-06-25 2012-05-17 Ampere Life Sciences, Inc. Treatment of pervasive developmental disorders with tocotrienols or tocotrienol enriched extracts
JP2011173949A (ja) * 2010-02-23 2011-09-08 Japan Polyethylene Corp ポリエチレン系樹脂組成物及びそれからなる食品包装容器
US9162957B2 (en) 2011-07-19 2015-10-20 Edison Pharmaceuticals, Inc. Methods for oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols
US9039898B2 (en) 2011-11-15 2015-05-26 Engineering Research Associates, Inc. Method for separating components in natural oil
US9719970B2 (en) 2012-11-30 2017-08-01 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin D metabolites
WO2015050655A1 (en) * 2013-08-30 2015-04-09 Inventure Renewables, Inc. Methods for the separation or purification of vitamin e, tocopherols and tocotrienols from lipid mixtures
US9512098B1 (en) 2014-02-03 2016-12-06 Board Of Trustees Of The University Of Arkansas Process of producing purified gamma- and delta-tocotrienols from tocol-rich oils or distillates
MX2016010238A (es) * 2014-02-11 2016-10-28 Evonik Membrane Extraction Tech Ltd Metodo para producir composiciones de aceites naturales enriquecidas con vitamina e, especialmente enriquecidas con tocotrienol.
DE102014009237A1 (de) 2014-06-24 2015-12-24 Weylchem Wiesbaden Gmbh Verfahren zur Gewinnung von Vitamin E, Sterolen und/oder Terpenen aus öligen oder fettigen Gemischen biologischer Herkunft
JP6786761B2 (ja) * 2015-05-26 2020-11-18 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． Ｓｆｃによるキラル異性体の分離
CN106317007B (zh) * 2015-06-15 2019-03-01 浙江医药股份有限公司新昌制药厂 一种从天然维生素E脚料回收d-α-生育酚的方法
CN106689422A (zh) * 2015-11-12 2017-05-24 中国石油天然气股份有限公司 抗氧化剂组合物及其应用
US10745371B2 (en) 2015-12-16 2020-08-18 Ptc Therapeutics, Inc. Methods for enriching alpha-tocotrienol from mixed tocol compositions
US10703701B2 (en) 2015-12-17 2020-07-07 Ptc Therapeutics, Inc. Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
US11154795B2 (en) 2016-10-21 2021-10-26 Novasep Equipment Solutions Use of compressed gas for moving eluent applied to chromatography
ES2959817T3 (es) * 2016-12-16 2024-02-28 Praj Industries Ltd Procedimiento para la preparación de tocoles y escualeno
CN108929303B (zh) * 2017-05-27 2020-12-15 浙江大学 一种利用聚离子液体从混合生育酚中分离单个生育酚的方法
MY184673A (en) * 2018-03-16 2021-04-15 Palm Nutraceuticals Sdn Bhd A process of preparing vitamin e concentrate
CN110412189A (zh) * 2018-04-27 2019-11-05 株式会社岛津制作所 一种快速检测油脂或生物样品中的维生素d的方法
CN110412139A (zh) 2018-04-27 2019-11-05 株式会社岛津制作所 一种分析系统

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HUT63158A (en) * 1990-05-23 1993-07-28 Lipogenics Inc Process for obtaining tokotrienols, tokoferols and tokotrienol-like compounds and pahrmaceutical compositions comprising same as active ingredient
DE69332946T2 (de) * 1992-10-16 2004-05-19 Suprex Corp. Automatisierte extrakion mittels eines superkritischen fluidum
US5972357A (en) * 1996-12-19 1999-10-26 Kikkoman Corporation Healthy foods and cosmetics
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MY127954A (en) * 1999-11-04 2007-01-31 Malaysian Palm Oil Board A method of chromatographic isolation for non-glyceride components
MY127451A (en) * 1999-11-04 2006-12-29 Malaysian Palm Oil Board A method of chromatographic isolation for vitamin e isomers

Non-Patent Citations (3)

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Title
A. STABY ET. AL. : "Quantitative analysis of marine oils by capillary supercritical fluid chromatography." CHROMATOGRAPHIA, vol. 39, no. 11, December 1994 (1994-12), pages 697-705, XP000999090 *
G. GALUBA ET. AL.: "Separation of tocopherols and sterols in soybean oil condensate utilising supercritical fluid chromatographs (SFC)" CHEMICAL ANALYSIS (WARSAW), vol. 42, - 1997 pages 245-8, XP000999091 *
T. YARITA ET. AL.: "Supercritical fluid chromatographic determination of tocopherols on an ODS-silica gel column. " JOURNAL OF CHROMATOGRAPHY, A, , vol. 679, 1994, pages 329-34, XP000999044 *

Also Published As

Publication number Publication date
AU783564B2 (en) 2005-11-10
JP2001261671A (ja) 2001-09-26
US20010044548A1 (en) 2001-11-22
JP5051943B2 (ja) 2012-10-17
CA2334068C (en) 2010-04-06
MY127451A (en) 2006-12-29
EP1122250A1 (de) 2001-08-08
DE60103431D1 (de) 2004-07-01
AU1826001A (en) 2001-08-09
US6656358B2 (en) 2003-12-02
DE60103431T2 (de) 2005-06-16
JP2012140467A (ja) 2012-07-26
CA2334068A1 (en) 2001-08-02
EP1122250B1 (de) 2004-05-26

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