SG97777A1 - Benezoheterocyclic compounds - Google Patents

Benezoheterocyclic compounds

Info

Publication number
SG97777A1
SG97777A1 SG9900120A SG1999000120A SG97777A1 SG 97777 A1 SG97777 A1 SG 97777A1 SG 9900120 A SG9900120 A SG 9900120A SG 1999000120 A SG1999000120 A SG 1999000120A SG 97777 A1 SG97777 A1 SG 97777A1
Authority
SG
Singapore
Prior art keywords
benezoheterocyclic
compounds
benezoheterocyclic compounds
Prior art date
Application number
SG9900120A
Other languages
English (en)
Inventor
Ueda Hiraki
Miyamoto Hisashi
Yamashita Hiroshi
Tone Hitoshi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SG97777A1 publication Critical patent/SG97777A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG9900120A 1987-04-16 1988-04-14 Benezoheterocyclic compounds SG97777A1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP9419887 1987-04-16
JP10235187 1987-04-24
JP10836187 1987-04-30
JP12659887 1987-05-22
JP14954487 1987-06-16
JP17612687 1987-07-14
JP28377687 1987-11-09
JP28710887 1987-11-12

Publications (1)

Publication Number Publication Date
SG97777A1 true SG97777A1 (en) 2003-08-20

Family

ID=27572879

Family Applications (3)

Application Number Title Priority Date Filing Date
SG200203819A SG101541A1 (en) 1987-04-16 1988-04-14 Benzoheterocyclic compounds
SG9900120A SG97777A1 (en) 1987-04-16 1988-04-14 Benezoheterocyclic compounds
SG1996007292A SG49836A1 (en) 1987-04-16 1988-04-14 Benzoheterocyclic compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG200203819A SG101541A1 (en) 1987-04-16 1988-04-14 Benzoheterocyclic compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG1996007292A SG49836A1 (en) 1987-04-16 1988-04-14 Benzoheterocyclic compounds

Country Status (13)

Country Link
US (5) US5563138A (de)
EP (3) EP0287951B1 (de)
JP (2) JPH0696557B2 (de)
KR (2) KR940002113B1 (de)
CN (1) CN1053666C (de)
CY (1) CY2050B1 (de)
DE (4) DE3855388T2 (de)
DK (2) DK170640B1 (de)
ES (3) ES2172734T3 (de)
HK (1) HK128797A (de)
NL (1) NL980011I2 (de)
SA (1) SA97180461A (de)
SG (3) SG101541A1 (de)

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US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
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WO1996022988A1 (fr) * 1995-01-24 1996-08-01 Hokuriku Seiyaku Co., Ltd. Derives de l'acide quiloleine carboxylique
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US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
EP1117406A1 (de) * 1998-09-30 2001-07-25 Alcon Laboratories, Inc. Antibiotische zusammensetzungen zur behandlung der auge, der nase und den ohren
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
DE19850788A1 (de) * 1998-11-04 2000-05-11 Clariant Gmbh Verfahren zur Herstellung von Trifluorbenzoesäuren
RU2270695C2 (ru) 1999-03-17 2006-02-27 Дайити Фармасьютикал Ко., Лтд. Фармацевтическая композиция
DE19962470A1 (de) * 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
WO2002041891A2 (en) * 2000-11-01 2002-05-30 The Procter & Gamble Company Hiv treatment with benzimidazoles
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
JP2005521712A (ja) * 2002-03-26 2005-07-21 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティー オブ アリゾナ 弱塩基の可溶化
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
CA2470365C (en) * 2002-11-20 2011-05-17 Japan Tobacco Inc. 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
US7164023B2 (en) 2003-09-04 2007-01-16 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
WO2005026147A1 (ja) * 2003-09-10 2005-03-24 Kyorin Pharmaceutical Co., Ltd. ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体
WO2005026145A2 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
ES2531190T3 (es) 2006-03-06 2015-03-11 Japan Tobacco Inc Método para producir un compuesto de 4-oxoquinolina
CN101437801B (zh) 2006-03-06 2013-02-06 日本烟草产业株式会社 制备4-氧代喹啉化合物的方法
EP2066672B1 (de) 2006-09-29 2015-06-24 Cipla Limited Verbessertes verfahren zur herstellung von temozolomid und analoga
US8222407B2 (en) * 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
EP2222662A4 (de) * 2007-11-15 2011-08-03 Univ Maryland Inhibitoren der kynurenin-aminotransferase
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CN106913569B (zh) * 2016-01-04 2022-04-22 广东工业大学 苯酞类化合物在制备抗耐药菌药物中的应用
CN112266326A (zh) * 2020-11-10 2021-01-26 杭州臻挚生物科技有限公司 二氯甲苯硝化物中间体的制备方法

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DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3420770A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-(3-oxo-1-piperazinyl)-3-chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Also Published As

Publication number Publication date
KR940002113B1 (ko) 1994-03-17
US5811576A (en) 1998-09-22
US5591744A (en) 1997-01-07
EP0823413A2 (de) 1998-02-11
DE3856434T2 (de) 2001-06-13
SG101541A1 (en) 2004-01-30
SA97180461A (ar) 2005-12-03
DE3856515T2 (de) 2002-08-14
DE3855388T2 (de) 1997-02-13
US5495020A (en) 1996-02-27
DK101492A (da) 1992-08-13
EP0287951A2 (de) 1988-10-26
EP0287951B1 (de) 1996-07-03
ES2091180T3 (es) 1996-11-01
EP0287951A3 (en) 1990-06-13
DE3855388D1 (de) 1996-08-08
DK207688A (da) 1988-10-17
EP0565132A2 (de) 1993-10-13
DK171820B1 (da) 1997-06-23
CN1053666C (zh) 2000-06-21
HK128797A (en) 1997-09-19
ES2172734T3 (es) 2002-10-01
DE3856515D1 (de) 2002-03-21
JPH07138232A (ja) 1995-05-30
EP0565132A3 (en) 1994-05-18
CY2050B1 (en) 1998-04-30
JPH0696557B2 (ja) 1994-11-30
JP2654537B2 (ja) 1997-09-17
KR880012506A (ko) 1988-11-28
EP0565132B1 (de) 2000-10-25
DE3856434D1 (de) 2000-11-30
EP0823413B1 (de) 2002-02-13
DK170640B1 (da) 1995-11-20
CN1030237A (zh) 1989-01-11
KR960006145B1 (ko) 1996-05-09
US5563138A (en) 1996-10-08
DK101492D0 (da) 1992-08-13
ES2152936T3 (es) 2001-02-16
EP0823413A3 (de) 1998-12-09
SG49836A1 (en) 1998-06-15
NL980011I2 (nl) 1998-10-01
DK207688D0 (da) 1988-04-15
NL980011I1 (nl) 1998-05-06
DE19775083I2 (de) 2001-06-13
US5723648A (en) 1998-03-03
JPH01230558A (ja) 1989-09-14

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