SG91796A1 - N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use - Google Patents
N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their useInfo
- Publication number
- SG91796A1 SG91796A1 SG9702412A SG1997002412A SG91796A1 SG 91796 A1 SG91796 A1 SG 91796A1 SG 9702412 A SG9702412 A SG 9702412A SG 1997002412 A SG1997002412 A SG 1997002412A SG 91796 A1 SG91796 A1 SG 91796A1
- Authority
- SG
- Singapore
- Prior art keywords
- thiazol
- aryl
- sulphonamide derivatives
- sulphonamide
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/50—Nitrogen atoms bound to hetero atoms
- C07D277/52—Nitrogen atoms bound to hetero atoms to sulfur atoms, e.g. sulfonamides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96111661 | 1996-07-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG91796A1 true SG91796A1 (en) | 2002-10-15 |
Family
ID=8223010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG9702412A SG91796A1 (en) | 1996-07-19 | 1997-07-09 | N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use |
Country Status (23)
Country | Link |
---|---|
US (2) | US5877193A (xx) |
EP (1) | EP0819681A3 (xx) |
JP (1) | JP2991679B2 (xx) |
KR (1) | KR100247672B1 (xx) |
CN (1) | CN1176101A (xx) |
AU (1) | AU725496B2 (xx) |
BR (1) | BR9704023A (xx) |
CA (1) | CA2210613A1 (xx) |
CO (1) | CO4900053A1 (xx) |
CZ (1) | CZ227397A3 (xx) |
HR (1) | HRP970393A2 (xx) |
HU (1) | HUP9701193A3 (xx) |
IL (1) | IL121298A (xx) |
MA (1) | MA24273A1 (xx) |
MX (1) | MX9705385A (xx) |
NO (1) | NO973338L (xx) |
NZ (1) | NZ328331A (xx) |
PE (1) | PE91298A1 (xx) |
PL (1) | PL321203A1 (xx) |
SG (1) | SG91796A1 (xx) |
TR (1) | TR199700653A2 (xx) |
YU (1) | YU30297A (xx) |
ZA (1) | ZA976222B (xx) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9725138D0 (en) * | 1997-11-27 | 1998-01-28 | Pharmacia & Upjohn Spa | Thiophenesulfonamide compounds |
GB9725141D0 (en) * | 1997-11-27 | 1998-01-28 | Pharmacia & Upjohn Spa | Benzenesulfonamide compounds |
US6211185B1 (en) | 1999-05-05 | 2001-04-03 | Veterinary Pharmacy Corporation | Concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution, and a suspending agent |
SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
HUP0303857A3 (en) * | 2000-12-13 | 2007-07-30 | Wyeth Corp | Heterocyclic sulifonamide inhibitors of beta amyloid production |
ES2346961T3 (es) | 2001-11-22 | 2010-10-22 | Biovitrum Ab | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa de tipo 1. |
US6869970B2 (en) * | 2002-02-04 | 2005-03-22 | Novartis Ag | Crystalline salt forms of valsartan |
FR2849598B1 (fr) * | 2003-01-07 | 2006-09-22 | Merck Sante Sas | Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans |
FR2849599B1 (fr) * | 2003-01-07 | 2006-12-29 | Merck Sante Sas | Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete |
JPWO2005054216A1 (ja) * | 2003-12-01 | 2007-06-28 | 株式会社リバース・プロテオミクス研究所 | 新規抗癌剤「スルコキシン」 |
EP2054397B1 (en) * | 2006-08-16 | 2015-10-07 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Small molecule inhibitors of kynurenine-3-monooxygenase |
EP2054056A4 (en) * | 2006-08-16 | 2010-08-25 | J David Gladstone Inst A Testa | SMALL MOLECULAR INHIBITORS OF KYNURENINE-3-MONOOXYGENASE |
WO2009123776A2 (en) * | 2008-01-15 | 2009-10-08 | Siga Technologies, Inc. | Antiviral drugs for treatment of arenavirus infection |
WO2009124086A2 (en) * | 2008-04-04 | 2009-10-08 | Siga Technologies, Inc. | Antibacterial drug for treatment of staphylococcus aureus and other gram-positive bacterial infections |
UA103319C2 (xx) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Сполуки бензенсульфонамідтіазолу та -оксазолу$соединения бензенсульфонамидтиазола и -оксазола |
CN101602687A (zh) * | 2008-06-13 | 2009-12-16 | 上海特化医药科技有限公司 | 6-硝基苯乙酮类化合物、其制备方法及用途 |
EA027451B1 (ru) * | 2011-08-30 | 2017-07-31 | Схди Фаундейшн, Инк. | Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и их применение |
CN102627589A (zh) * | 2012-04-05 | 2012-08-08 | 天津理工大学 | 一种两步合成制备4-异丙基苯磺酰氯的方法和工艺 |
CN102633687B (zh) * | 2012-04-05 | 2016-06-08 | 天津瑞岭化工有限公司 | 一种对位取代烷基苯磺酰氯的制备方法和工艺 |
CN102633695A (zh) * | 2012-04-05 | 2012-08-15 | 天津理工大学 | 一种4-异丙基苯磺酰氯的制备方法和工艺 |
CN102633696A (zh) * | 2012-04-05 | 2012-08-15 | 天津理工大学 | 一种两步合成制备对位取代烷基苯磺酰氯的方法和工艺 |
EP2897607B1 (en) * | 2012-09-21 | 2017-11-22 | Rhode Island Hospital | Inhibitors of beta-hydrolase for treatment of cancer |
JP6938545B2 (ja) | 2016-05-20 | 2021-09-22 | ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
KR20190086772A (ko) | 2016-12-09 | 2019-07-23 | 제논 파마슈티칼스 인크. | 벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 |
WO2019241533A1 (en) | 2018-06-13 | 2019-12-19 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
EP3844150A1 (en) | 2018-08-31 | 2021-07-07 | Xenon Pharmaceuticals Inc. | Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents |
US10752623B2 (en) | 2018-08-31 | 2020-08-25 | Xenon Pharmaceuticals Inc. | Heteroaryl-substituted sulfonamide compounds and their use as sodium channel inhibitors |
CN114516807B (zh) * | 2022-02-24 | 2023-11-17 | 南京大学 | 一种含硝基多取代芳香二胺单体及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0569193A1 (en) * | 1992-05-06 | 1993-11-10 | E.R. SQUIBB & SONS, INC. | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists |
WO1994027979A1 (en) * | 1993-05-20 | 1994-12-08 | Immunopharmaceutics, Inc. | Sulfonamides and derivatives thereof that modulate the activity of endothelin |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996016650A1 (fr) * | 1994-11-29 | 1996-06-06 | Hisamitsu Pharmaceutical Co., Inc. | Antibacterien et bactericide comprenant un derive de 2-aminothiazole et sels de ce derive |
GB9702194D0 (en) * | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
-
1997
- 1997-06-12 US US08/874,050 patent/US5877193A/en not_active Expired - Fee Related
- 1997-07-09 SG SG9702412A patent/SG91796A1/en unknown
- 1997-07-10 EP EP97111745A patent/EP0819681A3/de not_active Ceased
- 1997-07-11 YU YU30297A patent/YU30297A/sh unknown
- 1997-07-11 PE PE1997000613A patent/PE91298A1/es not_active Application Discontinuation
- 1997-07-14 ZA ZA9706222A patent/ZA976222B/xx unknown
- 1997-07-14 NZ NZ328331A patent/NZ328331A/xx unknown
- 1997-07-14 IL IL12129897A patent/IL121298A/xx not_active IP Right Cessation
- 1997-07-14 HU HU9701193A patent/HUP9701193A3/hu unknown
- 1997-07-16 JP JP9190990A patent/JP2991679B2/ja not_active Expired - Fee Related
- 1997-07-16 CA CA002210613A patent/CA2210613A1/en not_active Abandoned
- 1997-07-16 MX MX9705385A patent/MX9705385A/es not_active Application Discontinuation
- 1997-07-17 TR TR97/00653A patent/TR199700653A2/xx unknown
- 1997-07-17 CZ CZ972273A patent/CZ227397A3/cs unknown
- 1997-07-17 MA MA24722A patent/MA24273A1/fr unknown
- 1997-07-17 CO CO97040540A patent/CO4900053A1/es unknown
- 1997-07-18 NO NO973338A patent/NO973338L/no not_active Application Discontinuation
- 1997-07-18 CN CN97114715A patent/CN1176101A/zh active Pending
- 1997-07-18 AU AU28752/97A patent/AU725496B2/en not_active Ceased
- 1997-07-18 BR BR9704023A patent/BR9704023A/pt active Search and Examination
- 1997-07-18 PL PL97321203A patent/PL321203A1/xx unknown
- 1997-07-18 HR HR96111661.3A patent/HRP970393A2/xx not_active Application Discontinuation
- 1997-07-19 KR KR1019970033826A patent/KR100247672B1/ko not_active IP Right Cessation
-
1998
- 1998-11-20 US US09/197,070 patent/US5958910A/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0569193A1 (en) * | 1992-05-06 | 1993-11-10 | E.R. SQUIBB & SONS, INC. | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists |
WO1994027979A1 (en) * | 1993-05-20 | 1994-12-08 | Immunopharmaceutics, Inc. | Sulfonamides and derivatives thereof that modulate the activity of endothelin |
Also Published As
Publication number | Publication date |
---|---|
EP0819681A2 (de) | 1998-01-21 |
PE91298A1 (es) | 1998-12-31 |
NO973338L (no) | 1998-01-20 |
US5958910A (en) | 1999-09-28 |
HU9701193D0 (en) | 1997-09-29 |
HUP9701193A2 (hu) | 1999-02-01 |
TR199700653A2 (xx) | 1998-02-21 |
MA24273A1 (fr) | 1998-04-01 |
KR100247672B1 (ko) | 2000-04-01 |
MX9705385A (es) | 1998-04-30 |
NO973338D0 (no) | 1997-07-18 |
CZ227397A3 (cs) | 1998-02-18 |
ZA976222B (en) | 1998-01-19 |
HRP970393A2 (en) | 1998-04-30 |
AU2875297A (en) | 1998-01-29 |
US5877193A (en) | 1999-03-02 |
CA2210613A1 (en) | 1998-01-19 |
AU725496B2 (en) | 2000-10-12 |
CO4900053A1 (es) | 2000-03-27 |
BR9704023A (pt) | 1998-11-17 |
HUP9701193A3 (en) | 2000-08-28 |
IL121298A0 (en) | 1998-01-04 |
PL321203A1 (en) | 1998-02-02 |
KR980008228A (ko) | 1998-04-30 |
JPH1067761A (ja) | 1998-03-10 |
YU30297A (sh) | 2000-10-30 |
CN1176101A (zh) | 1998-03-18 |
EP0819681A3 (de) | 1998-02-04 |
IL121298A (en) | 2001-03-19 |
NZ328331A (en) | 1999-05-28 |
JP2991679B2 (ja) | 1999-12-20 |
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