SG52494A1 - 2-aminoalykl-5-aminoalkylamino substituted-isoquinoindazoles-6(2H)-ones - Google Patents

2-aminoalykl-5-aminoalkylamino substituted-isoquinoindazoles-6(2H)-ones

Info

Publication number
SG52494A1
SG52494A1 SG1996005180A SG1996005180A SG52494A1 SG 52494 A1 SG52494 A1 SG 52494A1 SG 1996005180 A SG1996005180 A SG 1996005180A SG 1996005180 A SG1996005180 A SG 1996005180A SG 52494 A1 SG52494 A1 SG 52494A1
Authority
SG
Singapore
Prior art keywords
alkyl
group
phenylalkyl
hydrogen
nr2r3
Prior art date
Application number
SG1996005180A
Other languages
English (en)
Inventor
A Paul Krapcho
Ernesto Menta
Abrogio Oliva
Silvano Spinelli
Original Assignee
Univ Vermont
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/103,641 external-priority patent/US5519029A/en
Application filed by Univ Vermont, Boehringer Mannheim Italia filed Critical Univ Vermont
Publication of SG52494A1 publication Critical patent/SG52494A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
SG1996005180A 1992-09-08 1993-09-08 2-aminoalykl-5-aminoalkylamino substituted-isoquinoindazoles-6(2H)-ones SG52494A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94160792A 1992-09-08 1992-09-08
US08/103,641 US5519029A (en) 1992-09-08 1993-08-11 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones

Publications (1)

Publication Number Publication Date
SG52494A1 true SG52494A1 (en) 1998-09-28

Family

ID=26800681

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996005180A SG52494A1 (en) 1992-09-08 1993-09-08 2-aminoalykl-5-aminoalkylamino substituted-isoquinoindazoles-6(2H)-ones

Country Status (17)

Country Link
EP (1) EP0662076B1 (fr)
JP (1) JP3497168B2 (fr)
CN (1) CN1051549C (fr)
AT (1) ATE200491T1 (fr)
AU (1) AU680431B2 (fr)
CZ (1) CZ288366B6 (fr)
DE (1) DE69330131T2 (fr)
DK (1) DK0662076T3 (fr)
ES (1) ES2155452T3 (fr)
FI (1) FI109538B (fr)
GR (1) GR3036175T3 (fr)
HU (1) HU220616B1 (fr)
NO (1) NO302618B1 (fr)
PT (1) PT662076E (fr)
RU (1) RU2130937C1 (fr)
SG (1) SG52494A1 (fr)
WO (1) WO1994006795A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5596097A (en) * 1994-03-08 1997-01-21 The University Of Vermont Hetero-annulated indazoles
AU713107B2 (en) * 1995-07-06 1999-11-25 University Of Vermont, The New pyrido-thiopyranoindazoles with antitumor activity
IT1277576B1 (it) * 1995-09-13 1997-11-11 Boehringer Mannheim Italia 2-2-(2-idrossietil) ammino etil -5- 2-metilammino etil ammino indazolo 4,3-gh isochinolin-6 (2h)-one come agente antitumorale
IT1286509B1 (it) * 1996-11-29 1998-07-15 Boehringer Mannheim Italia Derivati 2, 3, 4, 7-tetraidropiridoindazolo-(1,4)benzodiazepinici aventi attivita' antitumorale
US6747039B2 (en) 2002-03-12 2004-06-08 Albany Molecular Research, Inc. Aza-benzothiopyranoindazoles with antitumor activity
CN103787970A (zh) * 2014-01-14 2014-05-14 北京万全德众医药生物技术有限公司 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69211A (en) * 1982-07-23 1987-01-30 Warner Lambert Co Substituted anthra(1,9-cd)pyrazol-6(2h)-ones,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0662076B1 (fr) 2001-04-11
HUT70145A (en) 1995-09-28
PT662076E (pt) 2001-09-28
WO1994006795A1 (fr) 1994-03-31
DE69330131T2 (de) 2001-08-30
CN1101046A (zh) 1995-04-05
EP0662076A1 (fr) 1995-07-12
DK0662076T3 (da) 2001-05-07
FI109538B (fi) 2002-08-30
JPH08503933A (ja) 1996-04-30
AU4844193A (en) 1994-04-12
CN1051549C (zh) 2000-04-19
NO950877D0 (no) 1995-03-07
ATE200491T1 (de) 2001-04-15
GR3036175T3 (en) 2001-10-31
FI951023A (fi) 1995-03-31
AU680431B2 (en) 1997-07-31
JP3497168B2 (ja) 2004-02-16
RU95110932A (ru) 1996-12-27
ES2155452T3 (es) 2001-05-16
NO950877L (no) 1995-05-08
FI951023A0 (fi) 1995-03-06
HU9500676D0 (en) 1995-04-28
NO302618B1 (no) 1998-03-30
HU220616B1 (hu) 2002-03-28
CZ59895A3 (en) 1995-11-15
RU2130937C1 (ru) 1999-05-27
DE69330131D1 (de) 2001-05-17
CZ288366B6 (en) 2001-06-13

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