NO950877L - Aminoalkylamino-substituerte isokinoindazoloner med antitumoraktivitet - Google Patents

Aminoalkylamino-substituerte isokinoindazoloner med antitumoraktivitet

Info

Publication number
NO950877L
NO950877L NO950877A NO950877A NO950877L NO 950877 L NO950877 L NO 950877L NO 950877 A NO950877 A NO 950877A NO 950877 A NO950877 A NO 950877A NO 950877 L NO950877 L NO 950877L
Authority
NO
Norway
Prior art keywords
alkyl
group
phenylalkyl
hydrogen
nr2r3
Prior art date
Application number
NO950877A
Other languages
English (en)
Other versions
NO302618B1 (no
NO950877D0 (no
Inventor
Paul A Krapcho
Ernesto Menta
Ambrogio Oliva
Silvano Spinelli
Original Assignee
Univ Vermont
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/103,641 external-priority patent/US5519029A/en
Application filed by Univ Vermont, Boehringer Mannheim Italia filed Critical Univ Vermont
Publication of NO950877D0 publication Critical patent/NO950877D0/no
Publication of NO950877L publication Critical patent/NO950877L/no
Publication of NO302618B1 publication Critical patent/NO302618B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO950877A 1992-09-08 1995-03-07 Aminoalkylamino-substituerte isokinoindazoloner med antitumoraktivitet NO302618B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94160792A 1992-09-08 1992-09-08
US08/103,641 US5519029A (en) 1992-09-08 1993-08-11 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
PCT/US1993/008241 WO1994006795A1 (en) 1992-09-08 1993-09-08 2-aminoalkyl-5-aminoalkylamino substituted isoquinoindazole-6-(2h)-ones with antitumour activity

Publications (3)

Publication Number Publication Date
NO950877D0 NO950877D0 (no) 1995-03-07
NO950877L true NO950877L (no) 1995-05-08
NO302618B1 NO302618B1 (no) 1998-03-30

Family

ID=26800681

Family Applications (1)

Application Number Title Priority Date Filing Date
NO950877A NO302618B1 (no) 1992-09-08 1995-03-07 Aminoalkylamino-substituerte isokinoindazoloner med antitumoraktivitet

Country Status (17)

Country Link
EP (1) EP0662076B1 (no)
JP (1) JP3497168B2 (no)
CN (1) CN1051549C (no)
AT (1) ATE200491T1 (no)
AU (1) AU680431B2 (no)
CZ (1) CZ288366B6 (no)
DE (1) DE69330131T2 (no)
DK (1) DK0662076T3 (no)
ES (1) ES2155452T3 (no)
FI (1) FI109538B (no)
GR (1) GR3036175T3 (no)
HU (1) HU220616B1 (no)
NO (1) NO302618B1 (no)
PT (1) PT662076E (no)
RU (1) RU2130937C1 (no)
SG (1) SG52494A1 (no)
WO (1) WO1994006795A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5596097A (en) * 1994-03-08 1997-01-21 The University Of Vermont Hetero-annulated indazoles
JPH11513020A (ja) * 1995-07-06 1999-11-09 ユニバーシティ オブ バーモント 抗腫瘍活性を有する新規ピリド−チオピラノインダゾール類
IT1277576B1 (it) * 1995-09-13 1997-11-11 Boehringer Mannheim Italia 2-2-(2-idrossietil) ammino etil -5- 2-metilammino etil ammino indazolo 4,3-gh isochinolin-6 (2h)-one come agente antitumorale
IT1286509B1 (it) * 1996-11-29 1998-07-15 Boehringer Mannheim Italia Derivati 2, 3, 4, 7-tetraidropiridoindazolo-(1,4)benzodiazepinici aventi attivita' antitumorale
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US6747039B2 (en) 2002-03-12 2004-06-08 Albany Molecular Research, Inc. Aza-benzothiopyranoindazoles with antitumor activity
CN103787970A (zh) * 2014-01-14 2014-05-14 北京万全德众医药生物技术有限公司 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56782B1 (en) * 1982-07-23 1991-12-18 Warner Lambert Co Substituted anthra(1,9-cd)pyrazol-6(2h)-ones
JPH0676409B2 (ja) * 1990-11-22 1994-09-28 協和醗酵工業株式会社 ピラゾロアクリドン誘導体

Also Published As

Publication number Publication date
CZ59895A3 (en) 1995-11-15
HUT70145A (en) 1995-09-28
CZ288366B6 (en) 2001-06-13
DE69330131D1 (de) 2001-05-17
HU220616B1 (hu) 2002-03-28
SG52494A1 (en) 1998-09-28
AU680431B2 (en) 1997-07-31
PT662076E (pt) 2001-09-28
FI951023A7 (fi) 1995-03-31
RU2130937C1 (ru) 1999-05-27
EP0662076A1 (en) 1995-07-12
CN1051549C (zh) 2000-04-19
CN1101046A (zh) 1995-04-05
DE69330131T2 (de) 2001-08-30
EP0662076B1 (en) 2001-04-11
FI109538B (fi) 2002-08-30
JP3497168B2 (ja) 2004-02-16
WO1994006795A1 (en) 1994-03-31
AU4844193A (en) 1994-04-12
ES2155452T3 (es) 2001-05-16
NO302618B1 (no) 1998-03-30
JPH08503933A (ja) 1996-04-30
NO950877D0 (no) 1995-03-07
FI951023A0 (fi) 1995-03-06
HU9500676D0 (en) 1995-04-28
GR3036175T3 (en) 2001-10-31
ATE200491T1 (de) 2001-04-15
DK0662076T3 (da) 2001-05-07
RU95110932A (ru) 1996-12-27

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees