SG52147A1 - 5-Amino-8-methyl-7-pyrrolidinylquinoline-3- carboxylic acid derivative - Google Patents

5-Amino-8-methyl-7-pyrrolidinylquinoline-3- carboxylic acid derivative

Info

Publication number
SG52147A1
SG52147A1 SG1995000487A SG1995000487A SG52147A1 SG 52147 A1 SG52147 A1 SG 52147A1 SG 1995000487 A SG1995000487 A SG 1995000487A SG 1995000487 A SG1995000487 A SG 1995000487A SG 52147 A1 SG52147 A1 SG 52147A1
Authority
SG
Singapore
Prior art keywords
compounds
hydrogen atom
carboxylic acid
alkyl group
lower alkyl
Prior art date
Application number
SG1995000487A
Other languages
English (en)
Inventor
Yasuo Ito
Hideo Kato
Singo Yasuda
Noriyuki Kado
Toshihiko Yoshida
Yoichi Yamamoto
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Publication of SG52147A1 publication Critical patent/SG52147A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Epoxy Resins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG1995000487A 1993-08-27 1994-06-20 5-Amino-8-methyl-7-pyrrolidinylquinoline-3- carboxylic acid derivative SG52147A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23431093 1993-08-27
JP28627293 1993-10-22
JP7631894 1994-03-24

Publications (1)

Publication Number Publication Date
SG52147A1 true SG52147A1 (en) 1998-09-28

Family

ID=27302121

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1995000487A SG52147A1 (en) 1993-08-27 1994-06-20 5-Amino-8-methyl-7-pyrrolidinylquinoline-3- carboxylic acid derivative

Country Status (23)

Country Link
US (1) US5547962A (de)
EP (1) EP0641793B1 (de)
JP (1) JP2673937B2 (de)
KR (1) KR100218807B1 (de)
CN (1) CN1048242C (de)
AT (1) ATE144508T1 (de)
AU (1) AU676729B2 (de)
CA (1) CA2126118C (de)
CZ (1) CZ286524B6 (de)
DE (1) DE69400791T2 (de)
DK (1) DK0641793T3 (de)
ES (1) ES2096413T3 (de)
FI (1) FI113174B (de)
GR (1) GR3021715T3 (de)
HU (1) HU221952B1 (de)
IL (1) IL110060A (de)
MY (1) MY111702A (de)
NO (1) NO305515B1 (de)
NZ (1) NZ260851A (de)
PL (1) PL175870B1 (de)
SG (1) SG52147A1 (de)
TW (1) TW252107B (de)
UA (1) UA39859C2 (de)

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CA2210007A1 (en) * 1995-01-24 1996-08-01 Yasuo Ito Quinoline carboxylic acid
US6121285A (en) 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
WO1999014214A1 (en) 1997-09-15 1999-03-25 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
WO2000029369A1 (fr) * 1998-11-18 2000-05-25 Asahi Glass Company Ltd. Derives d'acide aminoacrylique et procede de production correspondant
CA2367373C (en) 1999-03-17 2011-09-20 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
CN1312131C (zh) * 2000-02-09 2007-04-25 第一制药株式会社 包含作为活性成分的吡啶酮羧酸的抗耐酸细菌药
US6825353B2 (en) 2000-02-25 2004-11-30 Daiichi Pharmaceutical Co., Ltd. Process for producing quinolonecarboxylic acids and intermediates thereof
IL151451A0 (en) * 2000-02-25 2003-04-10 Daiichi Seiyaku Co Process for producing quinolonecarboxylic acids and intermediates thereof
KR20010044286A (ko) * 2001-02-01 2001-06-05 남근수 알킬-3-(2,6-디할로겐-5-플루오로)-옥소-3-피리딘프로피오네이트의 제조방법
WO2006123767A1 (ja) 2005-05-20 2006-11-23 Daiichi Sankyo Company, Limited 不斉四置換炭素原子含有化合物の製法
US7842818B2 (en) * 2005-09-28 2010-11-30 Daiichi Sankyo Company, Limited Process for preparation of tetrasubstituted 5-azaspiro[2.4]- heptane derivatives and optically active intermediates thereof
MX2008012488A (es) * 2006-03-28 2008-10-10 Procter & Gamble Un proceso de acoplamiento para preparar intermedios de quinolona.
CA2647457C (en) * 2006-03-28 2011-05-24 The Procter & Gamble Company A hydride reduction process for preparing quinolone intermediates
SMP200800058B (it) * 2006-03-28 2009-09-07 Procter & Gamble Sali e polimorfi malati di un acido (3s, 5s) -7- [3-ammino-5-metilpiperidinil]-1-ciclopropil-1,4-diidro-8-metossi-4-osso-3-chinolincarbossilico
TWI362386B (en) * 2007-03-30 2012-04-21 Daiichi Sankyo Co Ltd A production method for the qunolon-carboxylic acid derivative
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens

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IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPH0635457B2 (ja) * 1985-06-28 1994-05-11 杏林製薬株式会社 ピリドンカルボン酸誘導体およびその製造方法
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
JPH0637489B2 (ja) * 1985-09-21 1994-05-18 杏林製薬株式会社 キノロンカルボン酸誘導体およびその製造方法
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
EP0242789A3 (de) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate und Verfahren zu ihrer Herstellung
ATE58538T1 (de) * 1986-07-04 1990-12-15 Chemie Linz Gmbh 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
US4771055A (en) * 1986-07-28 1988-09-13 Warner-Lambert Company 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
JPS63152318A (ja) * 1986-08-07 1988-06-24 Dainippon Pharmaceut Co Ltd 抗マイコプラズマ剤
US5190955A (en) * 1987-01-28 1993-03-02 Bayer Aktiengesellschaft Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
DE3702393A1 (de) * 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
JPS63275567A (ja) * 1987-05-07 1988-11-14 Dainippon Pharmaceut Co Ltd 新規キノリン誘導体、そのエステルおよびその塩
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
US5164392A (en) * 1987-10-16 1992-11-17 Dainippon Pharmaceutical Co., Ltd. Quinoline derivatives and antibacterial agent containing them
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JPH0219377A (ja) * 1988-07-08 1990-01-23 Kyorin Pharmaceut Co Ltd ８‐メチルキノロンカルボン酸誘導体
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
IE76284B1 (en) * 1988-09-22 1997-10-08 Abbott Lab Amino acid quinoline and naphthyridine derivatives
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
PT93420A (pt) * 1989-03-15 1990-11-07 Kanebo Ltd Processo para a preparacao de derivados de acido quinolinocarboxilico e de composicoes antibacterianas que os contem
EP0390215B1 (de) * 1989-03-30 1995-06-07 Wakunaga Seiyaku Kabushiki Kaisha Chinolon-Derivate und deren Salze, Verfahren zu deren Herstellung und diese enthaltende antibakterielle Wirkstoffe
CA2012681A1 (en) * 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
DE3910920A1 (de) * 1989-04-05 1990-10-11 Bayer Ag Enantiomerenreine 7-(3-amino-1-pyrrolidinyl)-chinolon- und -naphthyridoncarbonsaeuren
DE4032560A1 (de) * 1990-10-13 1992-04-16 Bayer Ag 7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate
CA2099591C (en) * 1990-12-05 2002-11-12 Rajeshwar Singh 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3- carboxylic acid compounds useful as antibacterial agents
US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
KR950014567B1 (ko) * 1991-08-01 1995-12-08 주식회사대웅제약 신규한 퀴놀론 카르복실산 유도체

Also Published As

Publication number Publication date
AU676729B2 (en) 1997-03-20
US5547962A (en) 1996-08-20
NO305515B1 (no) 1999-06-14
IL110060A0 (en) 1994-10-07
FI942976A0 (fi) 1994-06-21
UA39859C2 (uk) 2001-07-16
NZ260851A (en) 1996-03-26
CN1117491A (zh) 1996-02-28
CZ157494A3 (en) 1995-10-18
FI942976A (fi) 1995-02-28
ATE144508T1 (de) 1996-11-15
GR3021715T3 (en) 1997-02-28
PL304063A1 (en) 1995-03-06
MY111702A (en) 2000-11-30
CZ286524B6 (cs) 2000-05-17
KR950005823A (ko) 1995-03-20
JPH07309864A (ja) 1995-11-28
ES2096413T3 (es) 1997-03-01
EP0641793B1 (de) 1996-10-23
NO942309L (no) 1995-02-28
FI113174B (fi) 2004-03-15
DE69400791T2 (de) 1997-03-06
EP0641793A1 (de) 1995-03-08
DK0641793T3 (da) 1996-11-25
JP2673937B2 (ja) 1997-11-05
HU9401954D0 (en) 1994-09-28
AU6487094A (en) 1995-03-09
CA2126118C (en) 2001-02-06
IL110060A (en) 1999-10-28
HUT67259A (en) 1995-03-28
CN1048242C (zh) 2000-01-12
CA2126118A1 (en) 1995-02-28
TW252107B (de) 1995-07-21
NO942309D0 (no) 1994-06-17
HU221952B1 (hu) 2003-03-28
KR100218807B1 (ko) 1999-09-01
DE69400791D1 (de) 1996-11-28
PL175870B1 (pl) 1999-02-26

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