SG47012A1 - Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof - Google Patents

Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof

Info

Publication number
SG47012A1
SG47012A1 SG1996001913A SG1996001913A SG47012A1 SG 47012 A1 SG47012 A1 SG 47012A1 SG 1996001913 A SG1996001913 A SG 1996001913A SG 1996001913 A SG1996001913 A SG 1996001913A SG 47012 A1 SG47012 A1 SG 47012A1
Authority
SG
Singapore
Prior art keywords
compounds
preparation
substituted biphenyl
certain substituted
tetrazoles
Prior art date
Application number
SG1996001913A
Other languages
English (en)
Inventor
William V Murray
Ronald Russell
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of SG47012A1 publication Critical patent/SG47012A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG1996001913A 1991-11-01 1992-10-30 Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof SG47012A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/786,666 US5252753A (en) 1991-11-01 1991-11-01 Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof

Publications (1)

Publication Number Publication Date
SG47012A1 true SG47012A1 (en) 1998-03-20

Family

ID=25139265

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996001913A SG47012A1 (en) 1991-11-01 1992-10-30 Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof

Country Status (11)

Country Link
US (1) US5252753A (ja)
EP (1) EP0540356B1 (ja)
JP (1) JP3145813B2 (ja)
AT (1) ATE178058T1 (ja)
AU (1) AU651014B2 (ja)
CA (1) CA2081847A1 (ja)
DE (1) DE69228727T2 (ja)
DK (1) DK0540356T3 (ja)
ES (1) ES2130161T3 (ja)
GR (1) GR3030330T3 (ja)
SG (1) SG47012A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
CZ283315B6 (cs) * 1992-12-17 1998-02-18 Sankyo Company Limited Bifenylové deriváty, způsob výroby a farmaceutické prostředky k léčení hypertense a srdečních onemocnění, které tyto deriváty obsahují
WO1996013489A1 (en) * 1994-10-27 1996-05-09 Novartis Ag Process for the preparation of tetrazoles
FR2753705B1 (fr) * 1996-09-20 1999-08-06 Procede pour la preparation de derives de 4-methyl-biphenyle
WO2002083127A1 (fr) * 2001-04-09 2002-10-24 Tokai University Educational System Compositions inhibant la modification proteique
EP1571150A1 (en) * 2004-03-02 2005-09-07 Aventis Pharma Deutschland GmbH Process for the preparation of tryptase inhibitors
JP4511550B2 (ja) * 2004-09-02 2010-07-28 テバ ファーマシューティカル インダストリーズ リミティド オルメサルタンメドキソミルの調製法
EP1784398A1 (en) * 2004-09-02 2007-05-16 Teva Pharmaceutical Industries Ltd Purification of olmesartan medoxomil
US20070054948A1 (en) * 2004-09-02 2007-03-08 Lilach Hedvati Purification of olmesartan medoxomil
EP1749828A1 (en) 2005-08-04 2007-02-07 Farmaprojects S.L. Process for preparing an angiotensin II receptor antagonist
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US20130196971A1 (en) * 2010-09-17 2013-08-01 Christopher Joseph Aquino Fatty acid synthase inhibitors
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
DE69024556T2 (de) * 1989-07-28 1996-10-17 Merck & Co Inc Substituierte Triazolinone, Triazolinthione und Triazolinimine als Angiotensin II-Antagonisten
DE19675036I2 (de) * 1990-02-19 2004-10-21 Novartis Ag Acylverbindungen.
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process

Also Published As

Publication number Publication date
CA2081847A1 (en) 1993-05-02
US5252753A (en) 1993-10-12
JP3145813B2 (ja) 2001-03-12
AU2740492A (en) 1993-05-06
JPH05279350A (ja) 1993-10-26
DE69228727D1 (de) 1999-04-29
EP0540356A3 (en) 1993-08-25
ES2130161T3 (es) 1999-07-01
GR3030330T3 (en) 1999-09-30
DE69228727T2 (de) 1999-08-19
DK0540356T3 (da) 1999-10-11
ATE178058T1 (de) 1999-04-15
EP0540356B1 (en) 1999-03-24
EP0540356A2 (en) 1993-05-05
AU651014B2 (en) 1994-07-07

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