DK0540356T3 - Fremgangsmåde til fremstilling af visse substituerede biphenyltetrazolderivater - Google Patents

Fremgangsmåde til fremstilling af visse substituerede biphenyltetrazolderivater

Info

Publication number
DK0540356T3
DK0540356T3 DK92309968T DK92309968T DK0540356T3 DK 0540356 T3 DK0540356 T3 DK 0540356T3 DK 92309968 T DK92309968 T DK 92309968T DK 92309968 T DK92309968 T DK 92309968T DK 0540356 T3 DK0540356 T3 DK 0540356T3
Authority
DK
Denmark
Prior art keywords
biphenyltetrazole
derivatives
preparation
certain substituted
disclosed
Prior art date
Application number
DK92309968T
Other languages
English (en)
Inventor
William V Murray
Ronald Russell
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Application granted granted Critical
Publication of DK0540356T3 publication Critical patent/DK0540356T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK92309968T 1991-11-01 1992-10-30 Fremgangsmåde til fremstilling af visse substituerede biphenyltetrazolderivater DK0540356T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/786,666 US5252753A (en) 1991-11-01 1991-11-01 Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof

Publications (1)

Publication Number Publication Date
DK0540356T3 true DK0540356T3 (da) 1999-10-11

Family

ID=25139265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92309968T DK0540356T3 (da) 1991-11-01 1992-10-30 Fremgangsmåde til fremstilling af visse substituerede biphenyltetrazolderivater

Country Status (11)

Country Link
US (1) US5252753A (da)
EP (1) EP0540356B1 (da)
JP (1) JP3145813B2 (da)
AT (1) ATE178058T1 (da)
AU (1) AU651014B2 (da)
CA (1) CA2081847A1 (da)
DE (1) DE69228727T2 (da)
DK (1) DK0540356T3 (da)
ES (1) ES2130161T3 (da)
GR (1) GR3030330T3 (da)
SG (1) SG47012A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
JP3501484B2 (ja) * 1992-12-17 2004-03-02 三共株式会社 ビフェニル誘導体
DE69521904T2 (de) * 1994-10-27 2002-04-04 Novartis Ag, Basel Verfahren zur herstellung tetrazole
FR2753705B1 (fr) * 1996-09-20 1999-08-06 Procede pour la preparation de derives de 4-methyl-biphenyle
JPWO2002083127A1 (ja) * 2001-04-09 2004-09-30 宮田　敏男 蛋白修飾物生成抑制組成物
EP1571150A1 (en) * 2004-03-02 2005-09-07 Aventis Pharma Deutschland GmbH Process for the preparation of tryptase inhibitors
KR100953878B1 (ko) * 2004-09-02 2010-04-22 테바 파마슈티컬 인더스트리즈 리미티드 올메살탄 메독소밀의 정제
US20070054948A1 (en) * 2004-09-02 2007-03-08 Lilach Hedvati Purification of olmesartan medoxomil
JP4511550B2 (ja) * 2004-09-02 2010-07-28 テバ ファーマシューティカル インダストリーズ リミティド オルメサルタンメドキソミルの調製法
EP1749828A1 (en) 2005-08-04 2007-02-07 Farmaprojects S.L. Process for preparing an angiotensin II receptor antagonist
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012037298A1 (en) * 2010-09-17 2012-03-22 Glaxosmithkline Llc Fatty acid synthase inhibitors
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
EP0412594B1 (en) * 1989-07-28 1996-01-03 Merck & Co. Inc. Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists
DE122007000050I1 (de) * 1990-02-19 2007-11-08 Novartis Ag Acylverbindungen
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process

Also Published As

Publication number Publication date
US5252753A (en) 1993-10-12
DE69228727D1 (de) 1999-04-29
EP0540356B1 (en) 1999-03-24
JP3145813B2 (ja) 2001-03-12
SG47012A1 (en) 1998-03-20
ATE178058T1 (de) 1999-04-15
AU651014B2 (en) 1994-07-07
EP0540356A3 (en) 1993-08-25
DE69228727T2 (de) 1999-08-19
CA2081847A1 (en) 1993-05-02
JPH05279350A (ja) 1993-10-26
ES2130161T3 (es) 1999-07-01
AU2740492A (en) 1993-05-06
EP0540356A2 (en) 1993-05-05
GR3030330T3 (en) 1999-09-30

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