JPS6445389A - 3-amino-4-(dihydroxyphosphinyl)butanoic acid and production thereof - Google Patents
3-amino-4-(dihydroxyphosphinyl)butanoic acid and production thereofInfo
- Publication number
- JPS6445389A JPS6445389A JP20088187A JP20088187A JPS6445389A JP S6445389 A JPS6445389 A JP S6445389A JP 20088187 A JP20088187 A JP 20088187A JP 20088187 A JP20088187 A JP 20088187A JP S6445389 A JPS6445389 A JP S6445389A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- expressed
- dihydroxyphosphinyl
- amino
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound expressed by formula I. USE:A synthetic intermediate for peptide derivatives capable of exhibiting physiological activity and antimicrobial properties, industrially, economically and advantageously available in a simplified process. PREPARATION:A 4-iodomethylazetidin-2-one expressed by formula II is reacted with a trialkyl phosphite expressed by the formula P(OR)3 (R is 1-8C alkyl) to provide a 4-(dialkoxyphosphinylmethyl)azetidin-2-one expressed by formula III, which is then hydrolyzed. Furthermore, the compound expressed by formula II which is a starting material is readily obtained by mixing chlorosulfonyl isocyanate with allyl iodide at a low temperature.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20088187A JPS6445389A (en) | 1987-08-13 | 1987-08-13 | 3-amino-4-(dihydroxyphosphinyl)butanoic acid and production thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20088187A JPS6445389A (en) | 1987-08-13 | 1987-08-13 | 3-amino-4-(dihydroxyphosphinyl)butanoic acid and production thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6445389A true JPS6445389A (en) | 1989-02-17 |
JPH0523275B2 JPH0523275B2 (en) | 1993-04-02 |
Family
ID=16431792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP20088187A Granted JPS6445389A (en) | 1987-08-13 | 1987-08-13 | 3-amino-4-(dihydroxyphosphinyl)butanoic acid and production thereof |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6445389A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5136725A (en) * | 1989-11-16 | 1992-08-11 | Sportartikel Fabrik Karl Uhl Gmbh | Sports glove, in particular for goalies |
-
1987
- 1987-08-13 JP JP20088187A patent/JPS6445389A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5136725A (en) * | 1989-11-16 | 1992-08-11 | Sportartikel Fabrik Karl Uhl Gmbh | Sports glove, in particular for goalies |
Also Published As
Publication number | Publication date |
---|---|
JPH0523275B2 (en) | 1993-04-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313111 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
EXPY | Cancellation because of completion of term |