SG192464A1 - 5-phenyl-isoxazole-3-carboxamides modulating hsp90 with antitumoral activities - Google Patents
5-phenyl-isoxazole-3-carboxamides modulating hsp90 with antitumoral activities Download PDFInfo
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- SG192464A1 SG192464A1 SG2013051305A SG2013051305A SG192464A1 SG 192464 A1 SG192464 A1 SG 192464A1 SG 2013051305 A SG2013051305 A SG 2013051305A SG 2013051305 A SG2013051305 A SG 2013051305A SG 192464 A1 SG192464 A1 SG 192464A1
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- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
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- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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| WO2009131951A2 (en) * | 2008-04-21 | 2009-10-29 | Institute For Oneworld Health | Compounds, compositions and methods comprising isoxazole derivatives |
| US8343976B2 (en) | 2009-04-20 | 2013-01-01 | Institute For Oneworld Health | Compounds, compositions and methods comprising pyrazole derivatives |
| EP2632849A4 (en) | 2010-10-27 | 2014-12-31 | Pixelligent Technologies Llc | SYNTHESIS, COVERAGE AND DISPERSION OF NANOCRYSTALLES |
| KR101275264B1 (ko) | 2011-08-24 | 2013-06-17 | 포항공과대학교 산학협력단 | 샤프로닌 단백질의 조절 물질 탐색 방법 |
| CN103724269B (zh) * | 2012-10-11 | 2016-12-21 | 中国科学院上海药物研究所 | 苯基1,2-异噁唑或苯基1,2-吡唑类化合物及其用途 |
| WO2015143004A1 (en) * | 2014-03-18 | 2015-09-24 | Synta Pharmaceuticals Corp. | Targeted therapeutics |
| WO2016054560A1 (en) * | 2014-10-02 | 2016-04-07 | Flatley Discovery Lab | Isoxazole compounds and methods for the treatment of cystic fibrosis |
| EP3236959B1 (en) | 2014-12-23 | 2025-09-24 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 (cdk7) |
| CN104725329B (zh) * | 2015-01-13 | 2017-01-18 | 陕西科技大学 | 一种具有抗肿瘤活性的异恶唑羧酸类化合物及其合成方法 |
| CA2978518C (en) | 2015-03-27 | 2023-11-21 | Nathanael S. Gray | Inhibitors of cyclin-dependent kinases |
| CN104803934B (zh) * | 2015-05-04 | 2018-01-02 | 陕西科技大学 | 一种具有抗肿瘤活性的苯基异噁唑羧酸类化合物及其合成方法与应用 |
| IT201700081419A1 (it) * | 2017-07-18 | 2019-01-18 | Rare Partners Srl | Derivati isossazolici come induttori di emoglobina fetale in precursori eritroidi derivati da pazienti beta-talassemici |
| WO2020005807A1 (en) | 2018-06-25 | 2020-01-02 | Dana-Farber Cancer Institute, Inc. | Taire family kinase inhibitors and uses thereof |
| EP3902542A4 (en) | 2018-12-28 | 2022-09-07 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 and uses thereof |
| CN117105880B (zh) * | 2022-10-17 | 2025-08-26 | 上海康斯维克生物医药有限公司 | 用作诱发抗原特异性反应的脲类化合物、其荧光标记物及制备方法和用途 |
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| EP1258484B1 (en) * | 2000-02-18 | 2009-01-14 | Kyowa Hakko Kirin Co., Ltd. | Novel isoxazole and thiazole compounds and use thereof as drugs |
| EA009919B1 (ru) * | 2003-02-11 | 2008-04-28 | Вернэлис (Кембридж) Лимитед | Соединения изоксазола |
| KR101394245B1 (ko) * | 2005-12-30 | 2014-05-14 | 에스케이바이오팜 주식회사 | 아이속사졸 유도체 및 이의 용도 |
| GB0603880D0 (en) * | 2006-02-27 | 2006-04-05 | Novartis Ag | Organic compounds |
| JP2010520176A (ja) * | 2007-03-01 | 2010-06-10 | ノバルティス アーゲー | ５−（２，４−ジヒドロキシ−５−イソプロピル−フェニル）−４−（４−モルホリン−４−イルメチル−フェニル）−イソオキサゾール−３−カルボン酸エチルアミドの酸付加塩、水和物および多形、ならびにこれらの形態を含む製剤 |
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- 2009-06-30 MX MX2010013913A patent/MX2010013913A/es active IP Right Grant
- 2009-06-30 CN CN2009801255931A patent/CN102083804A/zh active Pending
- 2009-06-30 CA CA2729710A patent/CA2729710A1/en not_active Abandoned
- 2009-06-30 NZ NZ590861A patent/NZ590861A/xx not_active IP Right Cessation
- 2009-06-30 MY MYPI20105887 patent/MY150604A/en unknown
- 2009-06-30 JP JP2011515438A patent/JP5640002B2/ja not_active Expired - Fee Related
- 2009-06-30 BR BRPI0913834A patent/BRPI0913834A2/pt not_active IP Right Cessation
- 2009-06-30 US US13/001,652 patent/US8383616B2/en not_active Expired - Fee Related
- 2009-06-30 WO PCT/EP2009/058205 patent/WO2010000748A1/en not_active Ceased
- 2009-06-30 SG SG2013051305A patent/SG192464A1/en unknown
- 2009-07-03 AR ARP090102496A patent/AR072793A1/es unknown
-
2010
- 2010-12-23 IL IL210200A patent/IL210200A0/en unknown
-
2011
- 2011-01-03 ZA ZA2011/00007A patent/ZA201100007B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010013913A (es) | 2011-03-03 |
| EA201170139A1 (ru) | 2011-08-30 |
| AU2009265745A1 (en) | 2010-01-07 |
| KR20110050615A (ko) | 2011-05-16 |
| EA019793B1 (ru) | 2014-06-30 |
| TW201012815A (en) | 2010-04-01 |
| CA2729710A1 (en) | 2010-01-07 |
| MY150604A (en) | 2014-01-30 |
| JP5640002B2 (ja) | 2014-12-10 |
| ZA201100007B (en) | 2011-10-26 |
| IL210200A0 (en) | 2011-03-31 |
| CN102083804A (zh) | 2011-06-01 |
| AR072793A1 (es) | 2010-09-22 |
| TWI450898B (zh) | 2014-09-01 |
| NZ590861A (en) | 2012-08-31 |
| EP2310377A1 (en) | 2011-04-20 |
| US8383616B2 (en) | 2013-02-26 |
| US20110245221A1 (en) | 2011-10-06 |
| WO2010000748A1 (en) | 2010-01-07 |
| EP2310377B1 (en) | 2015-09-16 |
| AU2009265745B2 (en) | 2013-07-04 |
| JP2011526594A (ja) | 2011-10-13 |
| BRPI0913834A2 (pt) | 2015-10-20 |
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