JP2013518923A5 - - Google Patents
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- Publication number
- JP2013518923A5 JP2013518923A5 JP2012552469A JP2012552469A JP2013518923A5 JP 2013518923 A5 JP2013518923 A5 JP 2013518923A5 JP 2012552469 A JP2012552469 A JP 2012552469A JP 2012552469 A JP2012552469 A JP 2012552469A JP 2013518923 A5 JP2013518923 A5 JP 2013518923A5
- Authority
- JP
- Japan
- Prior art keywords
- single bond
- represented
- bond
- following structure
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- FEOLNMRUZBLTJM-UGFGJWANSA-N CC(C)[C@@H](C(NC(C)(Cc1cc(O)ccc1)C(N(CCC1)NC1C(O[C@@H](C/C=C/C=C/[C@@H]([C@H](C)[C@@H](C)[C@H]1CCC(C)=O)O)/C(/C)=C/C=C/C(N2OCCCC2)=O)=O)=O)=O)NC1=O Chemical compound CC(C)[C@@H](C(NC(C)(Cc1cc(O)ccc1)C(N(CCC1)NC1C(O[C@@H](C/C=C/C=C/[C@@H]([C@H](C)[C@@H](C)[C@H]1CCC(C)=O)O)/C(/C)=C/C=C/C(N2OCCCC2)=O)=O)=O)=O)NC1=O FEOLNMRUZBLTJM-UGFGJWANSA-N 0.000 description 1
- 0 CC(C)[C@@](C(NC(C1)([C@@]1c1cc(O)ccc1)C(N(CCCC1C(O[C@@](CC=CC=C[C@@]([C@](C)[C@]([C@]2CCC(C)=O)O*)O)C(C)=CC=CC(*)=O)=O)C1C=N)=O)=O)NC2=O Chemical compound CC(C)[C@@](C(NC(C1)([C@@]1c1cc(O)ccc1)C(N(CCCC1C(O[C@@](CC=CC=C[C@@]([C@](C)[C@]([C@]2CCC(C)=O)O*)O)C(C)=CC=CC(*)=O)=O)C1C=N)=O)=O)NC2=O 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1002097.2A GB201002097D0 (en) | 2010-02-09 | 2010-02-09 | Novel compounds |
| GB1002097.2 | 2010-02-09 | ||
| GB1006128.1 | 2010-04-13 | ||
| GBGB1006128.1A GB201006128D0 (en) | 2010-04-13 | 2010-04-13 | Novel compounds |
| GBGB1101085.7A GB201101085D0 (en) | 2011-01-21 | 2011-01-21 | Novel compounds |
| GB1101085.7 | 2011-01-21 | ||
| PCT/GB2011/050236 WO2011098809A1 (en) | 2010-02-09 | 2011-02-09 | Sanglifehrin based compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013518923A JP2013518923A (ja) | 2013-05-23 |
| JP2013518923A5 true JP2013518923A5 (enExample) | 2015-11-19 |
| JP5894935B2 JP5894935B2 (ja) | 2016-03-30 |
Family
ID=43836693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552469A Expired - Fee Related JP5894935B2 (ja) | 2010-02-09 | 2011-02-09 | サングリフェリン系化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9119853B2 (enExample) |
| EP (1) | EP2533784B1 (enExample) |
| JP (1) | JP5894935B2 (enExample) |
| AU (1) | AU2011214135B2 (enExample) |
| BR (1) | BR112012019866A8 (enExample) |
| CA (1) | CA2788761C (enExample) |
| ES (1) | ES2541853T3 (enExample) |
| MX (1) | MX2012008873A (enExample) |
| WO (1) | WO2011098809A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201008123D0 (en) * | 2010-05-17 | 2010-06-30 | Biotica Tech Ltd | Novel compounds |
| JO3063B1 (ar) * | 2011-03-29 | 2017-03-15 | Neurovive Pharmaceutical Ab | مركب مبتكر وطرق لانتاجه |
| GB201118334D0 (en) * | 2011-10-24 | 2011-12-07 | Biotica Tech Ltd | Novel dosage form |
| CA3043131A1 (en) | 2016-11-18 | 2018-05-24 | Neurovive Pharmaceutical Ab | Use of sanglifehrin macrocyclic analogues as anticancer compounds |
| CN113498342A (zh) * | 2018-12-21 | 2021-10-12 | 锐新医药公司 | 参与协同结合的化合物和其用途 |
| CN114786777A (zh) | 2019-11-04 | 2022-07-22 | 锐新医药公司 | Ras抑制剂 |
| AU2021345111B2 (en) | 2020-09-15 | 2025-11-27 | Revolution Medicines, Inc. | Indole derivatives as Ras inhibitors in the treatment of cancer |
| AR125782A1 (es) | 2021-05-05 | 2023-08-16 | Revolution Medicines Inc | Inhibidores de ras |
| CR20230558A (es) | 2021-05-05 | 2024-01-24 | Revolution Medicines Inc | Inhibidores de ras para el tratamiento del cáncer |
| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR006514A1 (es) | 1995-07-04 | 1999-09-08 | Sandoz Ag | Un macrolido, sus usos, un proceso para producirlo, un aislado biologicamente puro capaz de producirlo, y una composicion farmaceutica quelo comprende |
| US6124453A (en) | 1995-07-04 | 2000-09-26 | Novartis Ag | Macrolides |
| DK0910633T3 (da) | 1996-07-05 | 2010-03-29 | Biotica Tech Ltd | Hybrid polyketidsyntase I-gen |
| GB9814622D0 (en) | 1998-07-06 | 1998-09-02 | Biotica Tech Ltd | Polyketides,their preparation,and materials for use therein |
| AR054778A1 (es) | 2005-06-17 | 2007-07-18 | Novartis Ag | Uso de sangliferina en hcv |
| JP5801534B2 (ja) | 2007-01-04 | 2015-10-28 | デビオファーム インターナショナル ソシエテ アノニム | ウールリッヒ型先天筋ジストロフィーの処置のための、非免疫抑制性シクロスポリン |
| US8962329B2 (en) | 2008-09-24 | 2015-02-24 | Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences | Gene cluster |
| JO3063B1 (ar) | 2011-03-29 | 2017-03-15 | Neurovive Pharmaceutical Ab | مركب مبتكر وطرق لانتاجه |
-
2011
- 2011-02-09 AU AU2011214135A patent/AU2011214135B2/en not_active Ceased
- 2011-02-09 CA CA2788761A patent/CA2788761C/en not_active Expired - Fee Related
- 2011-02-09 EP EP20110704308 patent/EP2533784B1/en not_active Not-in-force
- 2011-02-09 MX MX2012008873A patent/MX2012008873A/es active IP Right Grant
- 2011-02-09 WO PCT/GB2011/050236 patent/WO2011098809A1/en not_active Ceased
- 2011-02-09 ES ES11704308.3T patent/ES2541853T3/es active Active
- 2011-02-09 US US13/575,212 patent/US9119853B2/en active Active
- 2011-02-09 JP JP2012552469A patent/JP5894935B2/ja not_active Expired - Fee Related
- 2011-02-09 BR BR112012019866A patent/BR112012019866A8/pt not_active Application Discontinuation
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