SG181628A1 - Vaccine compositions - Google Patents

Vaccine compositions Download PDF

Info

Publication number
SG181628A1
SG181628A1 SG2012042784A SG2012042784A SG181628A1 SG 181628 A1 SG181628 A1 SG 181628A1 SG 2012042784 A SG2012042784 A SG 2012042784A SG 2012042784 A SG2012042784 A SG 2012042784A SG 181628 A1 SG181628 A1 SG 181628A1
Authority
SG
Singapore
Prior art keywords
klh
composition
peptide
concentration
linker
Prior art date
Application number
SG2012042784A
Other languages
English (en)
Inventor
Syed Saleem Ahmed
Iii John Joseph Buckley
Lavinia Marina Lewis
Brandi Rae Osborne
Sandipan Sinha
Jennifer Marie Thorn
Ferhana Zaman
Original Assignee
Celldex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celldex Therapeutics Inc filed Critical Celldex Therapeutics Inc
Publication of SG181628A1 publication Critical patent/SG181628A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001104Epidermal growth factor receptors [EGFR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/62Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG2012042784A 2009-12-22 2010-12-08 Vaccine compositions SG181628A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28908309P 2009-12-22 2009-12-22
PCT/IB2010/055674 WO2011077309A2 (en) 2009-12-22 2010-12-08 Vaccine compositions

Publications (1)

Publication Number Publication Date
SG181628A1 true SG181628A1 (en) 2012-07-30

Family

ID=43797591

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2012042784A SG181628A1 (en) 2009-12-22 2010-12-08 Vaccine compositions
SG10201408505SA SG10201408505SA (en) 2009-12-22 2010-12-08 Vaccine compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201408505SA SG10201408505SA (en) 2009-12-22 2010-12-08 Vaccine compositions

Country Status (13)

Country Link
US (3) US20130034573A1 (cg-RX-API-DMAC7.html)
EP (2) EP3257525A3 (cg-RX-API-DMAC7.html)
JP (2) JP6007105B2 (cg-RX-API-DMAC7.html)
KR (1) KR20120120185A (cg-RX-API-DMAC7.html)
CN (2) CN107412754A (cg-RX-API-DMAC7.html)
AU (1) AU2010334428B2 (cg-RX-API-DMAC7.html)
CA (1) CA2785585A1 (cg-RX-API-DMAC7.html)
IL (1) IL220308A0 (cg-RX-API-DMAC7.html)
MX (1) MX337070B (cg-RX-API-DMAC7.html)
NZ (2) NZ600978A (cg-RX-API-DMAC7.html)
RU (1) RU2581020C2 (cg-RX-API-DMAC7.html)
SG (2) SG181628A1 (cg-RX-API-DMAC7.html)
WO (1) WO2011077309A2 (cg-RX-API-DMAC7.html)

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KR101776976B1 (ko) * 2010-02-21 2017-09-08 바이엘 헬스케어 엘엘씨 생체분자의 활성화 및 접합 방법
KR101502360B1 (ko) * 2013-03-20 2015-03-25 주식회사 옵티팜 신규한 국내형 돼지생식기호흡기증후군 바이러스
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
SG11202100371RA (en) * 2018-07-19 2021-02-25 Helixmith Co Ltd Lyophilized pharmaceutical compositions for naked dna gene therapy
US20220273755A1 (en) * 2019-11-21 2022-09-01 Multiple Fortune Holding Limited Pharmaceutical composition, use and method for applying ganoderma microsporum immunomodulatory protein and keyhole limpet hemocyanin in carcinoma treatment

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Also Published As

Publication number Publication date
US20130034573A1 (en) 2013-02-07
EP2515934A2 (en) 2012-10-31
RU2012131162A (ru) 2014-01-27
CA2785585A1 (en) 2011-06-30
AU2010334428A1 (en) 2012-07-05
MX337070B (es) 2016-02-11
JP2013515049A (ja) 2013-05-02
JP6007105B2 (ja) 2016-10-12
NZ600978A (en) 2014-08-29
WO2011077309A3 (en) 2011-10-06
MX2012007283A (es) 2012-07-30
WO2011077309A2 (en) 2011-06-30
JP2015180667A (ja) 2015-10-15
EP3257525A3 (en) 2018-02-28
EP2515934B1 (en) 2017-05-17
EP3257525A2 (en) 2017-12-20
SG10201408505SA (en) 2015-02-27
CN102762224A (zh) 2012-10-31
KR20120120185A (ko) 2012-11-01
NZ629256A (en) 2016-02-26
CN107412754A (zh) 2017-12-01
US20190365886A1 (en) 2019-12-05
RU2581020C2 (ru) 2016-04-10
JP6146927B2 (ja) 2017-06-14
US20150087815A1 (en) 2015-03-26
AU2010334428B2 (en) 2015-05-21
IL220308A0 (en) 2012-07-31

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