SG177219A1 - Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors - Google Patents

Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors Download PDF

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Publication number
SG177219A1
SG177219A1 SG2011092863A SG2011092863A SG177219A1 SG 177219 A1 SG177219 A1 SG 177219A1 SG 2011092863 A SG2011092863 A SG 2011092863A SG 2011092863 A SG2011092863 A SG 2011092863A SG 177219 A1 SG177219 A1 SG 177219A1
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SG
Singapore
Prior art keywords
leukemia
hdac
drug resistant
inhibitor
combination
Prior art date
Application number
SG2011092863A
Other languages
English (en)
Inventor
Janine Arts
Peter Willem Jan Hellemans
Michel Marie Francois Janicot
Martin John Page
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG177219A1 publication Critical patent/SG177219A1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG2011092863A 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors SG177219A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06120726 2006-09-15
US91589507P 2007-05-03 2007-05-03

Publications (1)

Publication Number Publication Date
SG177219A1 true SG177219A1 (en) 2012-01-30

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SG2011092863A SG177219A1 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Country Status (12)

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CN (1) CN101516374B (zh)
BR (1) BRPI0716992A2 (zh)
DK (1) DK2066327T3 (zh)
ES (1) ES2399670T3 (zh)
ME (1) ME01514B (zh)
NZ (1) NZ575030A (zh)
PT (1) PT2066327E (zh)
RS (1) RS52638B (zh)
SG (1) SG177219A1 (zh)
SI (1) SI2066327T1 (zh)
UA (1) UA97249C2 (zh)
ZA (1) ZA200901818B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957066B2 (en) * 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
CN107095871A (zh) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat,一种新型的高效抗疟药物
WO2018017858A1 (en) * 2016-07-20 2018-01-25 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and compositions and uses thereof
CN114409638B (zh) * 2022-02-09 2023-02-14 深圳大学 组蛋白去乙酰化酶8选择性降解剂、制备方法及其在抗肿瘤活性中的应用
CN115028678B (zh) * 2022-07-08 2024-09-06 杭州医学院 基于vhl配体诱导bcr-abl蛋白降解的双功能分子及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781639B1 (en) * 2004-07-28 2012-01-25 Janssen Pharmaceutica NV Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

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Publication number Publication date
PT2066327E (pt) 2013-02-06
NZ575030A (en) 2012-07-27
CN101516374B (zh) 2013-04-24
ME01514B (me) 2014-04-20
ZA200901818B (en) 2010-05-26
SI2066327T1 (sl) 2013-04-30
DK2066327T3 (da) 2013-02-11
CN101516374A (zh) 2009-08-26
ES2399670T3 (es) 2013-04-02
UA97249C2 (ru) 2012-01-25
BRPI0716992A2 (pt) 2013-09-17
RS52638B (en) 2013-06-28

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