BRPI0716992A2 - inibidores da histona desacetilase com atividade combinada sobre as histona desacetilases classe i e classe iib em combinaÇço com inibidores da proteossoma - Google Patents
inibidores da histona desacetilase com atividade combinada sobre as histona desacetilases classe i e classe iib em combinaÇço com inibidores da proteossomaInfo
- Publication number
- BRPI0716992A2 BRPI0716992A2 BRPI0716992-2A2A BRPI0716992A BRPI0716992A2 BR PI0716992 A2 BRPI0716992 A2 BR PI0716992A2 BR PI0716992 A BRPI0716992 A BR PI0716992A BR PI0716992 A2 BRPI0716992 A2 BR PI0716992A2
- Authority
- BR
- Brazil
- Prior art keywords
- class
- histone
- inhibitors
- combination
- combined activity
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
INIBIDORES DA HISTONA DESACETILASE COM ATIVIDADE COMBINADA SOBRE AS HISTONA DESACETILASES CLASSE I E CLASSE IIB EM COMBINAÇçO COM INIBIDORES DA PROTEOSSOMA. A presente invenção refere-se a combinações de um inibidor da proteossoma e de um inibidor da histona desacetilase pelo inibidor com atividade combinada sobre histona desacetilases classe I e classe IIB, para inibir o crescimento de células tumorais, úteis no tratamento do câncer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06120726 | 2006-09-15 | ||
US91589507P | 2007-05-03 | 2007-05-03 | |
PCT/EP2007/059518 WO2008031817A2 (en) | 2006-09-15 | 2007-09-11 | Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0716992A2 true BRPI0716992A2 (pt) | 2013-09-17 |
Family
ID=41040414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0716992-2A2A BRPI0716992A2 (pt) | 2006-09-15 | 2007-09-11 | inibidores da histona desacetilase com atividade combinada sobre as histona desacetilases classe i e classe iib em combinaÇço com inibidores da proteossoma |
Country Status (12)
Country | Link |
---|---|
CN (1) | CN101516374B (pt) |
BR (1) | BRPI0716992A2 (pt) |
DK (1) | DK2066327T3 (pt) |
ES (1) | ES2399670T3 (pt) |
ME (1) | ME01514B (pt) |
NZ (1) | NZ575030A (pt) |
PT (1) | PT2066327E (pt) |
RS (1) | RS52638B (pt) |
SG (1) | SG177219A1 (pt) |
SI (1) | SI2066327T1 (pt) |
UA (1) | UA97249C2 (pt) |
ZA (1) | ZA200901818B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8957066B2 (en) * | 2011-02-28 | 2015-02-17 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
CN107095871A (zh) * | 2016-02-22 | 2017-08-29 | 中国科学院上海巴斯德研究所 | Quisinostat,一种新型的高效抗疟药物 |
WO2018017858A1 (en) * | 2016-07-20 | 2018-01-25 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and compositions and uses thereof |
CN114409638B (zh) * | 2022-02-09 | 2023-02-14 | 深圳大学 | 组蛋白去乙酰化酶8选择性降解剂、制备方法及其在抗肿瘤活性中的应用 |
CN115028678B (zh) * | 2022-07-08 | 2024-09-06 | 杭州医学院 | 基于vhl配体诱导bcr-abl蛋白降解的双功能分子及其制备方法和应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1781639B1 (en) * | 2004-07-28 | 2012-01-25 | Janssen Pharmaceutica NV | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
-
2007
- 2007-09-11 SI SI200731143T patent/SI2066327T1/sl unknown
- 2007-09-11 PT PT78033974T patent/PT2066327E/pt unknown
- 2007-09-11 UA UAA200900388A patent/UA97249C2/ru unknown
- 2007-09-11 RS RS20130038A patent/RS52638B/en unknown
- 2007-09-11 ME MEP-2013-15A patent/ME01514B/me unknown
- 2007-09-11 DK DK07803397.4T patent/DK2066327T3/da active
- 2007-09-11 SG SG2011092863A patent/SG177219A1/en unknown
- 2007-09-11 ES ES07803397T patent/ES2399670T3/es active Active
- 2007-09-11 CN CN200780034143.2A patent/CN101516374B/zh active Active
- 2007-09-11 NZ NZ575030A patent/NZ575030A/en unknown
- 2007-09-11 BR BRPI0716992-2A2A patent/BRPI0716992A2/pt not_active Application Discontinuation
-
2009
- 2009-03-13 ZA ZA200901818A patent/ZA200901818B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT2066327E (pt) | 2013-02-06 |
NZ575030A (en) | 2012-07-27 |
CN101516374B (zh) | 2013-04-24 |
ME01514B (me) | 2014-04-20 |
SG177219A1 (en) | 2012-01-30 |
ZA200901818B (en) | 2010-05-26 |
SI2066327T1 (sl) | 2013-04-30 |
DK2066327T3 (da) | 2013-02-11 |
CN101516374A (zh) | 2009-08-26 |
ES2399670T3 (es) | 2013-04-02 |
UA97249C2 (ru) | 2012-01-25 |
RS52638B (en) | 2013-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |