DK2066327T3 - Histondeacetylaseinhibitorer med kombineret aktivitet mod klassse I- og klasse IIB-histondeacetylaser i kombination med proteasominihibitorer - Google Patents

Histondeacetylaseinhibitorer med kombineret aktivitet mod klassse I- og klasse IIB-histondeacetylaser i kombination med proteasominihibitorer

Info

Publication number
DK2066327T3
DK2066327T3 DK07803397.4T DK07803397T DK2066327T3 DK 2066327 T3 DK2066327 T3 DK 2066327T3 DK 07803397 T DK07803397 T DK 07803397T DK 2066327 T3 DK2066327 T3 DK 2066327T3
Authority
DK
Denmark
Prior art keywords
class
inhibitors
combination
activity against
histone
Prior art date
Application number
DK07803397.4T
Other languages
Danish (da)
English (en)
Inventor
Janine Arts
Peter Willem Jan Hellemans
Martin John Page
Michel Marie Francois Janicot
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority claimed from PCT/EP2007/059518 external-priority patent/WO2008031817A2/en
Application granted granted Critical
Publication of DK2066327T3 publication Critical patent/DK2066327T3/da

Links

DK07803397.4T 2006-09-15 2007-09-11 Histondeacetylaseinhibitorer med kombineret aktivitet mod klassse I- og klasse IIB-histondeacetylaser i kombination med proteasominihibitorer DK2066327T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06120726 2006-09-15
US91589507P 2007-05-03 2007-05-03
PCT/EP2007/059518 WO2008031817A2 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Publications (1)

Publication Number Publication Date
DK2066327T3 true DK2066327T3 (da) 2013-02-11

Family

ID=41040414

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07803397.4T DK2066327T3 (da) 2006-09-15 2007-09-11 Histondeacetylaseinhibitorer med kombineret aktivitet mod klassse I- og klasse IIB-histondeacetylaser i kombination med proteasominihibitorer

Country Status (12)

Country Link
CN (1) CN101516374B (zh)
BR (1) BRPI0716992A2 (zh)
DK (1) DK2066327T3 (zh)
ES (1) ES2399670T3 (zh)
ME (1) ME01514B (zh)
NZ (1) NZ575030A (zh)
PT (1) PT2066327E (zh)
RS (1) RS52638B (zh)
SG (1) SG177219A1 (zh)
SI (1) SI2066327T1 (zh)
UA (1) UA97249C2 (zh)
ZA (1) ZA200901818B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957066B2 (en) * 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
CN107095871A (zh) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat,一种新型的高效抗疟药物
WO2018017858A1 (en) * 2016-07-20 2018-01-25 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and compositions and uses thereof
CN114409638B (zh) * 2022-02-09 2023-02-14 深圳大学 组蛋白去乙酰化酶8选择性降解剂、制备方法及其在抗肿瘤活性中的应用
CN115028678B (zh) * 2022-07-08 2024-09-06 杭州医学院 基于vhl配体诱导bcr-abl蛋白降解的双功能分子及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781639B1 (en) * 2004-07-28 2012-01-25 Janssen Pharmaceutica NV Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Also Published As

Publication number Publication date
PT2066327E (pt) 2013-02-06
NZ575030A (en) 2012-07-27
CN101516374B (zh) 2013-04-24
ME01514B (me) 2014-04-20
SG177219A1 (en) 2012-01-30
ZA200901818B (en) 2010-05-26
SI2066327T1 (sl) 2013-04-30
CN101516374A (zh) 2009-08-26
ES2399670T3 (es) 2013-04-02
UA97249C2 (ru) 2012-01-25
BRPI0716992A2 (pt) 2013-09-17
RS52638B (en) 2013-06-28

Similar Documents

Publication Publication Date Title
HK1136770A1 (en) Histone deacetylase inhibitors with combined activity on class-i and class- iib histone deacetylases in combination with proteasome inhibitors
HK1220179A1 (zh) 組蛋白去乙酰的抑制劑
HK1161583A1 (zh) 脫乙酰酶抑制劑和其用途
ZA200905060B (en) Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
HK1133199A1 (zh) 組蛋白脫乙酰基酶和微管蛋白脫乙酰基酶抑制劑
EP1973872A4 (en) HISTONDEACETYLASE HEMMER AND PROPHARMAKA THEREOF
IL188692A0 (en) Histone deacetylase inhibitors
EP1991247A4 (en) BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS
IL198263A0 (en) Hydroxamates as inhibitors of histone deacetylase
EP1735319A4 (en) Histone deacetylase INHIBITORS
EP1755601A4 (en) HISTONE DEACETYLASE INHIBITORS
EP1789381A4 (en) Histone deacetylase INHIBITORS
EP1945617A4 (en) HISTONDEACETYLASEINHIBITORS WITH ARYLPYRAZOLYL MOTIVES
EP2222162A4 (en) MYRISTATE INHIBITORS WITH SMALL BCR-ABL MOLECULES AND METHODS OF USE
EP1771167A4 (en) INHIBITORS OF HISTONE DEACETYLASE
EP1991226A4 (en) Histone deacetylase INHIBITORS
IL193458A0 (en) Histone deacetylase inhibitors
ZA200801351B (en) Sulphonypyrrole hydrochloride salts as histone deacetylases inhibitors
ZA200703390B (en) New histone deacetylases inhibitors
IL214244A (en) Diastylase Heisone Inhibitors and their use in healing
EP2308868A4 (en) HISTONDEACETYLASEINHIBITORS AND APPLICATIONS THEREOF
EP2208721A4 (en) HISTONE DEACETYLASE INHIBITOR, COMPOSITION AND USE THEREOF
DK2096167T3 (da) Aptamer mod midkin og anvendelse deraf
EP1784386A4 (en) HISTONE DEACETYLASE INHIBITORS
EP1784194A4 (en) HISTONE DEACETYLASE INHIBITORS