SG173642A1 - Influenza hemagglutinin and neuraminidase variants - Google Patents

Influenza hemagglutinin and neuraminidase variants Download PDF

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Publication number
SG173642A1
SG173642A1 SG2011057791A SG2011057791A SG173642A1 SG 173642 A1 SG173642 A1 SG 173642A1 SG 2011057791 A SG2011057791 A SG 2011057791A SG 2011057791 A SG2011057791 A SG 2011057791A SG 173642 A1 SG173642 A1 SG 173642A1
Authority
SG
Singapore
Prior art keywords
virus
seq
residues
influenza
polypeptide
Prior art date
Application number
SG2011057791A
Other languages
English (en)
Inventor
Hong Jin
Xing Cheng
Kanta Subbarao
Original Assignee
Medimmune Llc
Us Gov Nat Inst Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc, Us Gov Nat Inst Health filed Critical Medimmune Llc
Publication of SG173642A1 publication Critical patent/SG173642A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG2011057791A 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants SG173642A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15209409P 2009-02-12 2009-02-12
PCT/US2010/022970 WO2010093537A2 (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants

Publications (1)

Publication Number Publication Date
SG173642A1 true SG173642A1 (en) 2011-09-29

Family

ID=42562246

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011057791A SG173642A1 (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants
SG2014010185A SG2014010185A (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2014010185A SG2014010185A (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants

Country Status (11)

Country Link
US (2) US8613935B2 (enExample)
EP (1) EP2396033B1 (enExample)
JP (1) JP5818693B2 (enExample)
CN (1) CN102361649A (enExample)
AU (1) AU2010213966B2 (enExample)
BR (1) BRPI1008549A2 (enExample)
CA (1) CA2752205A1 (enExample)
MX (2) MX2011008497A (enExample)
RU (2) RU2535970C2 (enExample)
SG (2) SG173642A1 (enExample)
WO (1) WO2010093537A2 (enExample)

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AU2007286161B2 (en) 2006-08-09 2013-05-02 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
SG173642A1 (en) 2009-02-12 2011-09-29 Medimmune Llc Influenza hemagglutinin and neuraminidase variants
US8802110B2 (en) * 2010-09-21 2014-08-12 Massachusetts Institute Of Technology Influenza treatment and/or characterization, human-adapted HA polypeptides; vaccines
CN108103084B (zh) * 2017-11-21 2020-06-26 浙江迪福润丝生物科技有限公司 区分免疫和感染动物h5亚型禽流感疫苗株及其制备方法和应用

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Also Published As

Publication number Publication date
JP2012517239A (ja) 2012-08-02
EP2396033A2 (en) 2011-12-21
JP5818693B2 (ja) 2015-11-18
RU2011137404A (ru) 2013-03-20
CN102361649A (zh) 2012-02-22
MX343411B (es) 2016-11-04
EP2396033A4 (en) 2013-10-23
RU2014140731A (ru) 2016-04-27
US9119812B2 (en) 2015-09-01
MX2011008497A (es) 2011-12-16
AU2010213966A1 (en) 2011-09-01
US20140079726A1 (en) 2014-03-20
WO2010093537A3 (en) 2010-10-07
AU2010213966B2 (en) 2015-01-22
BRPI1008549A2 (pt) 2016-03-15
WO2010093537A2 (en) 2010-08-19
SG2014010185A (en) 2014-06-27
US8613935B2 (en) 2013-12-24
US20100330118A1 (en) 2010-12-30
RU2535970C2 (ru) 2014-12-20
EP2396033B1 (en) 2016-09-28
CA2752205A1 (en) 2010-08-19

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