JP5818693B2 - インフルエンザ赤血球凝集素およびノイラミニダーゼ変異体 - Google Patents

インフルエンザ赤血球凝集素およびノイラミニダーゼ変異体 Download PDF

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JP5818693B2
JP5818693B2 JP2011550155A JP2011550155A JP5818693B2 JP 5818693 B2 JP5818693 B2 JP 5818693B2 JP 2011550155 A JP2011550155 A JP 2011550155A JP 2011550155 A JP2011550155 A JP 2011550155A JP 5818693 B2 JP5818693 B2 JP 5818693B2
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residues
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sequences
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JP2012517239A (ja
JP2012517239A5 (enExample
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ジン，ホン
チェン，シン
スバラオ，カンタ
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メディミューン，エルエルシー
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ ナショナル インスティテューツ オブ ヘルス
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ ナショナル インスティテューツ オブ ヘルス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011550155A 2009-02-12 2010-02-03 インフルエンザ赤血球凝集素およびノイラミニダーゼ変異体 Expired - Fee Related JP5818693B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15209409P 2009-02-12 2009-02-12
US61/152,094 2009-02-12
PCT/US2010/022970 WO2010093537A2 (en) 2009-02-12 2010-02-03 Influenza hemagglutinin and neuraminidase variants

Publications (3)

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JP2012517239A JP2012517239A (ja) 2012-08-02
JP2012517239A5 JP2012517239A5 (enExample) 2013-03-14
JP5818693B2 true JP5818693B2 (ja) 2015-11-18

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US (2) US8613935B2 (enExample)
EP (1) EP2396033B1 (enExample)
JP (1) JP5818693B2 (enExample)
CN (1) CN102361649A (enExample)
AU (1) AU2010213966B2 (enExample)
BR (1) BRPI1008549A2 (enExample)
CA (1) CA2752205A1 (enExample)
MX (2) MX2011008497A (enExample)
RU (2) RU2535970C2 (enExample)
SG (2) SG173642A1 (enExample)
WO (1) WO2010093537A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610525Y2 (ja) 1986-02-06 1994-03-16 三洋電機株式会社 キヤプスタンモ−タ制御回路

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AU2005248377B2 (en) 2004-05-25 2011-03-24 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
KR101586968B1 (ko) 2006-08-09 2016-01-20 메디뮨 엘엘씨 인플루엔자 헤마글루티닌 및 뉴라미니다제 변이체
WO2010093537A2 (en) 2009-02-12 2010-08-19 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
AU2011305371B2 (en) * 2010-09-21 2015-05-21 Massachusetts Institute Of Technology Human-adapted HA polypeptides, vaccines, and influenza treatment
CN108103084B (zh) * 2017-11-21 2020-06-26 浙江迪福润丝生物科技有限公司 区分免疫和感染动物h5亚型禽流感疫苗株及其制备方法和应用

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610525Y2 (ja) 1986-02-06 1994-03-16 三洋電機株式会社 キヤプスタンモ−タ制御回路

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MX2011008497A (es) 2011-12-16
SG173642A1 (en) 2011-09-29
US20100330118A1 (en) 2010-12-30
AU2010213966A1 (en) 2011-09-01
MX343411B (es) 2016-11-04
AU2010213966B2 (en) 2015-01-22
BRPI1008549A2 (pt) 2016-03-15
JP2012517239A (ja) 2012-08-02
RU2011137404A (ru) 2013-03-20
SG2014010185A (en) 2014-06-27
EP2396033A4 (en) 2013-10-23
RU2535970C2 (ru) 2014-12-20
EP2396033B1 (en) 2016-09-28
WO2010093537A2 (en) 2010-08-19
US20140079726A1 (en) 2014-03-20
WO2010093537A3 (en) 2010-10-07
US8613935B2 (en) 2013-12-24
CN102361649A (zh) 2012-02-22
EP2396033A2 (en) 2011-12-21
RU2014140731A (ru) 2016-04-27
CA2752205A1 (en) 2010-08-19
US9119812B2 (en) 2015-09-01

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