SG168407A1 - Methods and compositions for the treatment of gastrointestinal disorders - Google Patents
Methods and compositions for the treatment of gastrointestinal disordersInfo
- Publication number
- SG168407A1 SG168407A1 SG200705302-8A SG2007053028A SG168407A1 SG 168407 A1 SG168407 A1 SG 168407A1 SG 2007053028 A SG2007053028 A SG 2007053028A SG 168407 A1 SG168407 A1 SG 168407A1
- Authority
- SG
- Singapore
- Prior art keywords
- disorders
- constipation
- conditions
- dyspepsia
- functional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44309803P | 2003-01-28 | 2003-01-28 | |
US47128803P | 2003-05-15 | 2003-05-15 | |
US51946003P | 2003-11-12 | 2003-11-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG168407A1 true SG168407A1 (en) | 2011-02-28 |
Family
ID=32854294
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2012003802A SG192300A1 (en) | 2003-01-28 | 2004-01-28 | Methods and compositions for the treatment of gastrointestinal disorders |
SG200705302-8A SG168407A1 (en) | 2003-01-28 | 2004-01-28 | Methods and compositions for the treatment of gastrointestinal disorders |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2012003802A SG192300A1 (en) | 2003-01-28 | 2004-01-28 | Methods and compositions for the treatment of gastrointestinal disorders |
Country Status (29)
Country | Link |
---|---|
US (3) | US20040266989A1 (fr) |
EP (3) | EP1911763B1 (fr) |
JP (3) | JP4584911B2 (fr) |
KR (2) | KR101227626B1 (fr) |
CN (2) | CN100589839C (fr) |
AT (2) | ATE365174T1 (fr) |
AU (2) | AU2004210161B2 (fr) |
BE (1) | BE2013C032I2 (fr) |
BR (2) | BRPI0407071B8 (fr) |
CA (1) | CA2514507C (fr) |
CY (5) | CY1110905T1 (fr) |
DE (2) | DE602004028678D1 (fr) |
DK (3) | DK1911763T3 (fr) |
ES (3) | ES2387848T3 (fr) |
FR (2) | FR13C0029I2 (fr) |
HK (1) | HK1078768A1 (fr) |
HU (1) | HUS1300022I1 (fr) |
IL (2) | IL169863A (fr) |
LT (1) | LTC1594517I2 (fr) |
LU (2) | LU92201I2 (fr) |
MX (1) | MXPA05008097A (fr) |
NL (1) | NL300593I2 (fr) |
NO (2) | NO334112B1 (fr) |
NZ (2) | NZ541595A (fr) |
PT (3) | PT1911763E (fr) |
RU (2) | RU2353383C2 (fr) |
SG (2) | SG192300A1 (fr) |
SI (3) | SI1911763T1 (fr) |
WO (1) | WO2004069165A2 (fr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102643333B (zh) | 2001-03-29 | 2019-04-23 | 药物协和公司 | 用于治疗组织炎症和癌变的鸟苷酸环化酶受体激动剂 |
US7371727B2 (en) * | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US20060281682A1 (en) * | 2003-01-28 | 2006-12-14 | Currie Mark G | Methods and compositions for the treatment of gastrointestinal disorders |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
SI1911763T1 (sl) * | 2003-01-28 | 2010-11-30 | Ironwood Pharmaceuticals Inc | Sestavki za zdravljenje gastrointestinalnih motenj |
US7494979B2 (en) * | 2003-06-13 | 2009-02-24 | Ironwood Pharmaceuticals, Inc. | Method for treating congestive heart failure and other disorders |
US20070010450A1 (en) * | 2003-06-13 | 2007-01-11 | Microbia, Inc., A Massachusetts Corporation | Methods and compositions for the treatment of gastrointestinal disorders |
WO2005115412A2 (fr) * | 2004-05-25 | 2005-12-08 | University Of Georgia Research Foundation, Inc. | Compositions et procedes de modulation d'une reponse immunitaire |
WO2006046746A1 (fr) * | 2004-10-26 | 2006-05-04 | Ajinomoto Co., Inc. | Agent préventif/thérapeutique pour des douleurs viscérales |
US20090253634A1 (en) * | 2005-08-19 | 2009-10-08 | Microbia, Inc. | Methods and Compositions for the Treatment of Gastrointestinal Disorders |
RU2566708C2 (ru) | 2005-09-29 | 2015-10-27 | Ипсен Фарма С.А.С. | Композиции и способы стимуляции двигательной функции желудочно-кишечного тракта |
WO2007101161A2 (fr) * | 2006-02-24 | 2007-09-07 | Ironwood Pharmaceuticals, Inc. | Méthodes et compositions servant au traitement de troubles gastro-intestinaux |
WO2008106429A2 (fr) * | 2007-02-26 | 2008-09-04 | Ironwood Pharmaceuticals, Inc. | Procédés et compositions pour le traitement de l'insuffisance cardiaque et d'autres troubles |
WO2008137318A1 (fr) * | 2007-05-04 | 2008-11-13 | Ironwood Pharmaceuticals, Inc. | Compositions et procédés de traitement de troubles associés à la rétention de sel ou de fluide |
US8969514B2 (en) * | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP2810951B1 (fr) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles |
WO2009149278A1 (fr) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utiles dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles |
US20110306125A1 (en) * | 2008-06-30 | 2011-12-15 | Ironwood Pharmaceuticals, Inc. | Protein Expression Methods |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
MX2011001620A (es) * | 2008-08-15 | 2011-03-25 | Ironwood Pharmaceuticals Inc | Formulaciones que contienen linaclotida para administracion oral. |
WO2010059733A1 (fr) | 2008-11-19 | 2010-05-27 | Forest Laboratories Holdings Limited | Forme cristalline de la linaclotide |
ES2608050T3 (es) | 2008-12-03 | 2017-04-05 | Synergy Pharmaceuticals Inc. | Formulaciones de agonistas de guanilato ciclasa C y métodos de uso |
ES2439998T3 (es) * | 2009-04-10 | 2014-01-27 | Corden Pharma Colorado, Inc. | Procedimiento para aislar linaclotida |
JP2013501071A (ja) * | 2009-08-06 | 2013-01-10 | アイロンウッド ファーマシューティカルズ, インコーポレイテッド | リナクロチドを含む処方物 |
US20130045239A1 (en) * | 2009-08-13 | 2013-02-21 | Ironwood Pharmaceuticals, Inc. | Method for Modulating the Pharmacodynamic Effect of Orally Administered Guanylate Cyclase Receptor Agonists |
AU2010314866B2 (en) * | 2009-11-09 | 2014-10-30 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
RU2012128509A (ru) * | 2009-12-07 | 2014-01-20 | Айронвуд Фармасьютикалз, Инк. | Способы лечения заболеваний желудочно-кишечного тракта |
PL2536742T3 (pl) | 2010-02-17 | 2017-11-30 | Ironwood Pharmaceuticals, Inc. | Leczenie zaburzeń żołądkowo-jelitowych |
WO2011145062A1 (fr) | 2010-05-21 | 2011-11-24 | Link Research & Grants Corporation | Traitement des acouphènes et de dysfonctions auditives apparentées |
WO2011156453A2 (fr) | 2010-06-09 | 2011-12-15 | Combimab, Inc. | Peptides thérapeutiques |
ES2919136T3 (es) | 2010-08-11 | 2022-07-22 | Ironwood Pharmaceuticals Inc | Formulaciones estables de linaclotida |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2810243C (fr) | 2010-09-15 | 2021-04-20 | Synergy Pharmaceuticals Inc. | Preparations d'agonistes du guanylate cyclase-c et methodes d'utilisation |
WO2012155114A1 (fr) | 2011-05-11 | 2012-11-15 | Ironwood Pharmaceuticals, Inc. | Nouveaux dérivés d'uroguanyline et leur utilisation pour le traitement des troubles gastro-intestinaux |
CA2835624A1 (fr) | 2011-05-11 | 2012-11-15 | Ironwood Pharmaceuticals, Inc. | Traitements de troubles gastro-intestinaux |
WO2012170804A1 (fr) | 2011-06-08 | 2012-12-13 | Ironwood Pharmaceuticals, Inc. | Traitements destinés à des troubles gastro-intestinaux |
WO2012170766A1 (fr) | 2011-06-08 | 2012-12-13 | Ironwood Pharmaceuticals, Inc. | Traitements de troubles gastro-intestinaux |
MD480Z5 (ro) * | 2011-07-07 | 2012-09-30 | Эльвира АНДОН | Metodă de tratament al colitei ulceroase nespecifice acute |
DK2776055T3 (en) | 2011-08-17 | 2017-03-06 | Ironwood Pharmaceuticals Inc | TREATMENTS FOR GASTROINTESTINAL DISORDERS |
EA022546B1 (ru) * | 2011-09-28 | 2016-01-29 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биоорганической Химии Им. Академиков М.М. Шемякина И Ю.А. Овчинникова Российской Академии Наук | Способ торможения роста карциномы эрлиха у лабораторного животного |
US20140018307A1 (en) * | 2012-07-12 | 2014-01-16 | Forest Laboratories Holdings Ltd. | Linaclotide compositions |
RU2528641C2 (ru) * | 2012-08-22 | 2014-09-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия им. Н.Н. Бурденко" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения больных с синдромом диспепсии в сочетании с избыточной массой тела |
CN102875655B (zh) * | 2012-09-29 | 2014-12-17 | 深圳翰宇药业股份有限公司 | 一种合成利那洛肽的方法 |
EP2950803A1 (fr) | 2013-01-30 | 2015-12-09 | Sandoz AG | Forme cristalline de linaclotide |
CA2905438A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
EP3030252B1 (fr) | 2013-08-09 | 2018-11-07 | Ardelyx, Inc. | Composés et procédés d'inhibition du transport de phosphate |
DK3288578T3 (da) * | 2015-05-01 | 2023-05-01 | Ironwood Pharmaceuticals Inc | Sammensætninger til colonrensning og behandling af gastrointestinale lidelser |
EP3430056A4 (fr) * | 2016-03-15 | 2019-11-20 | The Regents of the University of California | Méthodes et compositions pour traiter et prévenir des maladies associées à l'intégrine alpha 8 beta 1 |
CN107929718A (zh) * | 2017-10-19 | 2018-04-20 | 南京星银药业集团有限公司 | Glp‑1类似物及gc‑c受体激动剂组合物缓释制剂及其制备方法 |
CA3115178A1 (fr) * | 2018-10-23 | 2020-04-30 | Abk Biomedical Incorporated | Dispositif d'administration |
CN109467606A (zh) * | 2018-11-15 | 2019-03-15 | 大连理工大学 | 一种大肠杆菌肠毒素STa-LTB-STb融合蛋白及其编码基因和应用 |
US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
RU2712761C1 (ru) * | 2019-07-02 | 2020-01-31 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Средство для стимуляции регенерации эндотелия легких при сочетании метаболического синдрома и хронической обструктивной болезни легких |
CN111265653B (zh) * | 2020-02-09 | 2023-05-09 | 华中科技大学同济医学院附属协和医院 | 心房利钠肽在制备炎症性肠病治疗药物中的应用 |
WO2021191865A1 (fr) * | 2020-03-26 | 2021-09-30 | Dusa Pharmaceuticals, Inc. | Gestion de lésions de la neurofibromatose dermique |
WO2023144292A1 (fr) | 2022-01-28 | 2023-08-03 | Fresenius Kabi Ipsum S.R.L. | Procédé de préparation de linaclotide |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US121961A (en) * | 1871-12-19 | Improvement in devices for supporting pipe-cores | ||
US266989A (en) * | 1882-11-07 | Automatic fire | ||
US73628A (en) * | 1868-01-21 | mitchell | ||
US258687A (en) * | 1882-05-30 | Grain-binder | ||
US232013A (en) * | 1880-09-07 | Henry h | ||
US152868A (en) * | 1874-07-07 | Improvement in type-setting machines | ||
US32684A (en) * | 1861-07-02 | Stump-extkactob | ||
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
US6342373B1 (en) * | 1983-11-21 | 2002-01-29 | Ucp Gen-Pharma Ag | Process for preparing recombinant eglin, protease inhibitor |
IT1217123B (it) | 1987-02-05 | 1990-03-14 | Rotta Research Lab | Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione |
GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
CH679207A5 (fr) | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
CA2046830C (fr) | 1990-07-19 | 1999-12-14 | Patrick P. Deluca | Systeme d'administration des medicaments comprenant une interaction entre une proteine ou une polypeptide et un polymere hydrophobe biodegradable |
HUT64023A (en) | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
FR2674849B1 (fr) | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
CH683149A5 (fr) | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
US5140102A (en) | 1991-09-23 | 1992-08-18 | Monsanto Company | Pentadecapeptide, guanylin, which stimulates intestinal guanylate cyclase |
EP0619738B1 (fr) * | 1991-12-02 | 2003-07-09 | Millennium Pharmaceuticals, Inc. | Polypeptides d'immunoglobulines inhibiteurs se liant au recepteur beta humain du facteur de croissance d'origine plaquettaire |
US5824645A (en) | 1991-12-30 | 1998-10-20 | Neurex Corporation | Method of treating inflammation |
ATE165977T1 (de) | 1991-12-30 | 1998-05-15 | Neurex Corp | Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie |
GB9211268D0 (en) | 1992-05-28 | 1992-07-15 | Ici Plc | Salts of basic peptides with carboxyterminated polyesters |
US5969097A (en) * | 1992-06-23 | 1999-10-19 | G. D. Searle & Co. | Human guanylin |
CA2150574A1 (fr) | 1993-01-06 | 1994-07-21 | Shalaby W. Shalaby | Conjugues moleculaires ioniques de polyesters degradables et de polypeptides bioactifs |
US5672659A (en) | 1993-01-06 | 1997-09-30 | Kinerton Limited | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
US5395490A (en) | 1993-05-14 | 1995-03-07 | Intertec, Ltd. | Method for treating materials by the application of electromagnetic energy at resonant absorption frequencies |
CA2174928C (fr) * | 1993-10-26 | 2011-08-16 | Scott A. Waldman | Compositions se fixant specifiquement a des cellules cancereuses colo-rectales et procedes d'utilisation |
US5489670A (en) * | 1993-10-29 | 1996-02-06 | G. D. Searle & Co. | Human uroguanylin |
US5610145A (en) | 1994-04-15 | 1997-03-11 | Warner-Lambert Company | Tachykinin antagonists |
US5612052A (en) | 1995-04-13 | 1997-03-18 | Poly-Med, Inc. | Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof |
DE122005000043I2 (de) | 1995-06-27 | 2006-08-03 | Elan Pharm Inc | Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der progression neuropathischer Schmerzerkrankungen |
US6054429A (en) | 1996-03-08 | 2000-04-25 | Elan Pharmaceuticals, Inc. | Epidural method of producing analgesia |
US5795864A (en) | 1995-06-27 | 1998-08-18 | Neurex Corporation | Stable omega conopetide formulations |
SK66798A3 (en) | 1995-11-24 | 1999-01-11 | Smithkline Beecham Spa | Quinoline derivative, preparation method thereof, pharmaceutical composition containing the same and its use |
GB9524104D0 (en) | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
CA2250981C (fr) | 1996-04-23 | 2002-07-02 | Kinerton Limited | Polymeres polylactiques acides |
US6589750B2 (en) | 1997-02-20 | 2003-07-08 | Institut Pasteur | Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives |
WO1998037894A1 (fr) | 1997-02-28 | 1998-09-03 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Combinaison synergique d'inhibiteurs de la phosphodiesterase et d'agonistes de la cyclase d'adenylate ou d'agonistes de la cyclyse guanylique |
US5893985A (en) | 1997-03-14 | 1999-04-13 | The Lincoln Electric Company | Plasma arc torch |
NZ329807A (en) | 1997-04-23 | 2000-07-28 | Pfizer | NK-1 receptor antagonists and P receptor antagonists 2-Diarylmethyl-3-amino-1-azabicyclo[2.2.2]octane derivatives and amino substituted N-containing rings as agents for treating irritable bowel syndrome |
ATE273996T1 (de) | 1997-09-12 | 2004-09-15 | Pharis Biotec Gmbh | Zusammensetzung zur therapie von diabetes mellitus und fettsucht |
US20010006972A1 (en) | 1998-04-21 | 2001-07-05 | Stephen A. Williams | Nk-1 receptor antagonists for the treatment of symptoms of irritable bowel syndrome |
IT1304152B1 (it) | 1998-12-10 | 2001-03-08 | Mediolanum Farmaceutici Srl | Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato |
PT1185294E (pt) | 1999-06-23 | 2005-08-31 | Pasteur Institut | Metodos terapeuticos e composicoes para o tratamento de perturbacoes comportamentais e interpessoais enfraquecidas |
KR20020031407A (ko) | 1999-08-18 | 2002-05-01 | 다푸르 가브리에 | 펩타이드의 서방형 제제 |
SE9903291D0 (sv) | 1999-09-15 | 1999-09-15 | Astra Ab | New process |
EP1220872A1 (fr) | 1999-10-06 | 2002-07-10 | Pharmacia Corporation | Uroguanyline, anticancereux intestinal |
US6734188B1 (en) | 1999-11-01 | 2004-05-11 | John Rhodes | Composition for treatment of constipation and irritable bowel syndrome |
AUPQ514600A0 (en) | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
AU3580001A (en) | 2000-03-01 | 2001-09-12 | University College London | Modulators of the endocannabinoid uptake and of the vallinoid receptors |
DK1216707T3 (da) | 2000-12-22 | 2005-05-09 | Pasteur Institut | Fremgangsmåde til screening af ligandmolekyler, der specifikt binder til NEP-bindingsstederne for QHNPR-pentapeptidet |
WO2002062369A2 (fr) | 2001-02-02 | 2002-08-15 | Pharmacia Corporation | Combinaisons d'uroguanyline et d'inhibiteur de cyclooxygenase-2 pour l'inhibition du cancer de l'intestin |
CN102643333B (zh) * | 2001-03-29 | 2019-04-23 | 药物协和公司 | 用于治疗组织炎症和癌变的鸟苷酸环化酶受体激动剂 |
WO2002079235A2 (fr) | 2001-03-30 | 2002-10-10 | University Of Copenhagen | Compositions et procedes de modulation de l'activite du recepteur signalant la guanylyl cylclase et de traitement de la maladie de meniere |
MY134211A (en) | 2001-05-18 | 2007-11-30 | Smithkline Beecham Corp | Novel use |
DE10292434D2 (de) * | 2001-06-05 | 2004-07-29 | Yueksel Savas | Verwendung eines Peptids, welches Guanylat Cyclase C aktiviert, für die Behandlung von Atemwegserkrankungen über die Luftwege, Arzneimittel, Inhalationsvorrichtung und Diagnoseverfahren |
FR2830451B1 (fr) | 2001-10-09 | 2004-04-30 | Inst Nat Sante Rech Med | Utilisation de peptides analogues de la thymuline(pat)pour la fabrication de medicaments contre la douleur |
EP1321142A1 (fr) | 2001-12-21 | 2003-06-25 | Novartis AG | Forme solide pour l'administration orale du Tégaserode |
US20040121961A1 (en) * | 2002-02-04 | 2004-06-24 | Jaime Masferrer | Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer |
US20030232013A1 (en) * | 2002-02-22 | 2003-12-18 | Gary Sieckman | Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides |
EP1531846A4 (fr) | 2002-02-27 | 2006-04-19 | Us Gov Health & Human Serv | Conjugues de ligand, adaptateur et agent cytotoxique, compositions associees et procedes d'utilisation relatifs |
AU2003225837B2 (en) | 2002-03-15 | 2008-11-06 | Forest Laboratories Holdings Limited | NE and 5-HT reuptake inhibitors for treating visceral pain syndromes |
CN100411618C (zh) | 2002-05-17 | 2008-08-20 | 迪欧加药品公司 | 有效的选择性阿片受体调制剂化合物的用途 |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7371727B2 (en) * | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
SI1911763T1 (sl) * | 2003-01-28 | 2010-11-30 | Ironwood Pharmaceuticals Inc | Sestavki za zdravljenje gastrointestinalnih motenj |
US20060281682A1 (en) * | 2003-01-28 | 2006-12-14 | Currie Mark G | Methods and compositions for the treatment of gastrointestinal disorders |
US7304036B2 (en) * | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
WO2004071436A2 (fr) | 2003-02-10 | 2004-08-26 | Thomas Jefferson University | Utilisation de ligands gcc |
US20090253634A1 (en) | 2005-08-19 | 2009-10-08 | Microbia, Inc. | Methods and Compositions for the Treatment of Gastrointestinal Disorders |
-
2004
- 2004-01-28 SI SI200431521T patent/SI1911763T1/sl unknown
- 2004-01-28 EP EP07011869A patent/EP1911763B1/fr not_active Expired - Lifetime
- 2004-01-28 CA CA2514507A patent/CA2514507C/fr not_active Expired - Lifetime
- 2004-01-28 NZ NZ541595A patent/NZ541595A/en not_active IP Right Cessation
- 2004-01-28 EP EP10170038A patent/EP2246360B1/fr not_active Expired - Lifetime
- 2004-01-28 KR KR1020057013966A patent/KR101227626B1/ko active IP Right Grant
- 2004-01-28 WO PCT/US2004/002390 patent/WO2004069165A2/fr active Application Filing
- 2004-01-28 US US10/766,735 patent/US20040266989A1/en not_active Abandoned
- 2004-01-28 CN CN200480008533A patent/CN100589839C/zh not_active Expired - Lifetime
- 2004-01-28 EP EP04706011A patent/EP1594517B1/fr not_active Expired - Lifetime
- 2004-01-28 DK DK07011869.0T patent/DK1911763T3/da active
- 2004-01-28 NZ NZ570134A patent/NZ570134A/en not_active IP Right Cessation
- 2004-01-28 PT PT07011869T patent/PT1911763E/pt unknown
- 2004-01-28 DE DE602004028678T patent/DE602004028678D1/de not_active Expired - Lifetime
- 2004-01-28 DE DE602004007105T patent/DE602004007105T2/de not_active Expired - Lifetime
- 2004-01-28 BR BRPI0407071A patent/BRPI0407071B8/pt active IP Right Grant
- 2004-01-28 RU RU2005127058/15A patent/RU2353383C2/ru active
- 2004-01-28 MX MXPA05008097A patent/MXPA05008097A/es active IP Right Grant
- 2004-01-28 BR BR122018074353A patent/BR122018074353B8/pt active IP Right Grant
- 2004-01-28 CN CN2009102662250A patent/CN101787073B/zh not_active Expired - Lifetime
- 2004-01-28 PT PT10170038T patent/PT2246360E/pt unknown
- 2004-01-28 KR KR1020117019764A patent/KR101227627B1/ko active IP Right Grant
- 2004-01-28 ES ES10170038T patent/ES2387848T3/es not_active Expired - Lifetime
- 2004-01-28 RU RU2008147983/15A patent/RU2543350C2/ru active
- 2004-01-28 SI SI200431918T patent/SI2246360T1/sl unknown
- 2004-01-28 SG SG2012003802A patent/SG192300A1/en unknown
- 2004-01-28 JP JP2006503109A patent/JP4584911B2/ja not_active Expired - Lifetime
- 2004-01-28 ES ES04706011T patent/ES2285417T3/es not_active Expired - Lifetime
- 2004-01-28 ES ES07011869T patent/ES2350123T3/es not_active Expired - Lifetime
- 2004-01-28 AU AU2004210161A patent/AU2004210161B2/en active Active
- 2004-01-28 AT AT04706011T patent/ATE365174T1/de active
- 2004-01-28 PT PT04706011T patent/PT1594517E/pt unknown
- 2004-01-28 AT AT07011869T patent/ATE477268T1/de active
- 2004-01-28 DK DK04706011T patent/DK1594517T3/da active
- 2004-01-28 SI SI200430401T patent/SI1594517T1/sl unknown
- 2004-01-28 SG SG200705302-8A patent/SG168407A1/en unknown
- 2004-01-28 DK DK10170038.3T patent/DK2246360T3/da active
-
2005
- 2005-07-25 IL IL169863A patent/IL169863A/en active IP Right Grant
- 2005-08-18 NO NO20053864A patent/NO334112B1/no not_active IP Right Cessation
- 2005-11-23 HK HK05110618A patent/HK1078768A1/xx not_active IP Right Cessation
-
2007
- 2007-08-09 CY CY20071101072T patent/CY1110905T1/el unknown
- 2007-10-31 US US11/930,696 patent/US7704947B2/en not_active Expired - Lifetime
-
2009
- 2009-11-10 AU AU2009235993A patent/AU2009235993B2/en active Active
-
2010
- 2010-04-05 US US12/754,138 patent/US8080526B2/en not_active Expired - Lifetime
- 2010-06-22 JP JP2010141519A patent/JP5563384B2/ja not_active Expired - Lifetime
- 2010-11-04 CY CY20101101000T patent/CY1111058T1/el unknown
-
2012
- 2012-08-09 IL IL221380A patent/IL221380A0/en active IP Right Grant
- 2012-09-19 CY CY20121100859T patent/CY1113217T1/el unknown
-
2013
- 2013-02-28 JP JP2013038602A patent/JP5748791B2/ja not_active Expired - Lifetime
- 2013-04-05 NO NO20130460A patent/NO336768B1/no not_active IP Right Cessation
- 2013-05-22 LT LTPA2013013C patent/LTC1594517I2/lt unknown
- 2013-05-22 HU HUS1300022 patent/HUS1300022I1/hu unknown
- 2013-05-22 LU LU92201C patent/LU92201I2/fr unknown
- 2013-05-22 LU LU92200C patent/LU92200I2/fr unknown
- 2013-05-22 NL NL300593C patent/NL300593I2/nl unknown
- 2013-05-23 FR FR13C0029C patent/FR13C0029I2/fr active Active
- 2013-05-23 FR FR13C0030C patent/FR13C0030I1/fr active Active
- 2013-05-24 CY CY2013022C patent/CY2013022I1/el unknown
- 2013-05-24 CY CY2013021C patent/CY2013021I1/el unknown
- 2013-05-24 BE BE2013C032C patent/BE2013C032I2/nl unknown
Non-Patent Citations (2)
Title |
---|
ISOLATION AND NUCLEOTIDE SEQUENCE DETERMINATION OF A GENE ENCODING A HEAT- STABLE ENTEROTOXIN OF ESCHERICHIA COLI * |
THERAPEUTIC APPLICATIONS OF GUANYLATE CYCLASE-C RECEPTOR AGONISTS * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG168407A1 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
SG153824A1 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2005016244A3 (fr) | Methodes et compositions pour le traitement de troubles gastro-intestinaux | |
WO2007022531A3 (fr) | Compositions et methodes de traitement de troubles gastro-intestinaux | |
WO2006086653A3 (fr) | Procedes et compositions pour le traitement de troubles gastro-intestinaux | |
WO2007101158A3 (fr) | Méthodes et compositions servant au traitement de troubles gastro-intestinaux | |
WO2008002971A3 (fr) | Procédés et compositions destinés au traitement de troubles gastro-intestinaux | |
MX340234B (es) | Tratamiento para transtornos gastrointestinales. | |
WO2005074575A3 (fr) | Procedes et compositions pour traiter des troubles gastro-intestinaux | |
IL171356A (en) | Anti-interferon receptor antibody for treatment of inflammatory bowel disease | |
WO2007062168A3 (fr) | Procede et compositions pour le traitement de desordres gastrointestinaux | |
CY1113569T1 (el) | Μεθοδοι και συνθεσεις για την αγωγη γαστρεντερικων διαταραχων |