SG164282A1 - Taxane derivatives functionalized at the 14-position and a process for the preparation thereof - Google Patents

Taxane derivatives functionalized at the 14-position and a process for the preparation thereof

Info

Publication number
SG164282A1
SG164282A1 SG200703232-9A SG2007032329A SG164282A1 SG 164282 A1 SG164282 A1 SG 164282A1 SG 2007032329 A SG2007032329 A SG 2007032329A SG 164282 A1 SG164282 A1 SG 164282A1
Authority
SG
Singapore
Prior art keywords
preparation
taxane derivatives
formula
derivatives functionalized
functionalized
Prior art date
Application number
SG200703232-9A
Other languages
English (en)
Inventor
Gabriele Fontana
Ezio Bombardelli
Arturo Battaglia
Eleonora Baldelli
Andrea Guerrini
Maria Luisa Gelmi
Giacomo Carenzi
Donato Pocar
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of SG164282A1 publication Critical patent/SG164282A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SG200703232-9A 2002-09-10 2003-09-05 Taxane derivatives functionalized at the 14-position and a process for the preparation thereof SG164282A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001921A ITMI20021921A1 (it) 2002-09-10 2002-09-10 Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.

Publications (1)

Publication Number Publication Date
SG164282A1 true SG164282A1 (en) 2010-09-29

Family

ID=31986024

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200703232-9A SG164282A1 (en) 2002-09-10 2003-09-05 Taxane derivatives functionalized at the 14-position and a process for the preparation thereof

Country Status (20)

Country Link
US (1) US7498452B2 (de)
EP (6) EP1980557A3 (de)
JP (2) JP4690039B2 (de)
KR (1) KR101096918B1 (de)
CN (1) CN1681799A (de)
AT (1) ATE398113T1 (de)
AU (1) AU2003267049B8 (de)
CA (1) CA2498277C (de)
DE (1) DE60321577D1 (de)
DK (4) DK2077264T3 (de)
ES (4) ES2398324T3 (de)
IL (5) IL167336A (de)
IT (1) ITMI20021921A1 (de)
NO (3) NO332250B1 (de)
PL (4) PL402333A1 (de)
PT (4) PT2264019E (de)
RU (1) RU2320652C2 (de)
SG (1) SG164282A1 (de)
SI (4) SI2264019T1 (de)
WO (1) WO2004024706A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
CN107056767B (zh) * 2015-12-04 2022-07-15 江苏恩华络康药物研发有限公司 用于制备水溶性紫杉烷类衍生物的方法及中间体

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022856A1 (en) * 1993-03-26 1994-10-13 The Research Foundation Of The State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5821363A (en) * 1994-01-28 1998-10-13 Pharmacia & Upjohn Company Antineoplastic use and pharmaceutical compositions containing them
WO2002012215A1 (en) * 2000-08-10 2002-02-14 Indena S.P.A. Process for the preparation of baccatin iii derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504222A (en) 1993-08-20 1996-04-02 The Scripps Research Institute Transformations of taxol
IL108444A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C2 taxane derivatives and pharmaceutical compositions containing them
US5719177A (en) 1994-11-04 1998-02-17 Pharmacia S.P.A. Taxane derivatives
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
JP2004506069A (ja) * 2000-08-04 2004-02-26 センサーズ・フォー・メデセン・アンド・サイエンス・インコーポレーテッド 水性環境中での検体検出
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022856A1 (en) * 1993-03-26 1994-10-13 The Research Foundation Of The State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5821363A (en) * 1994-01-28 1998-10-13 Pharmacia & Upjohn Company Antineoplastic use and pharmaceutical compositions containing them
WO2002012215A1 (en) * 2000-08-10 2002-02-14 Indena S.P.A. Process for the preparation of baccatin iii derivatives

Also Published As

Publication number Publication date
EP2298754B1 (de) 2013-08-07
ATE398113T1 (de) 2008-07-15
WO2004024706A2 (en) 2004-03-25
CA2498277C (en) 2011-07-05
ES2307965T3 (es) 2008-12-01
PL402332A1 (pl) 2013-04-02
IL167336A (en) 2009-11-18
EP2077264A2 (de) 2009-07-08
PL402333A1 (pl) 2013-04-02
DK1537093T3 (da) 2008-10-27
IL214431A0 (en) 2011-09-27
EP2298754B9 (de) 2013-12-18
ES2432024T3 (es) 2013-11-29
RU2005106361A (ru) 2005-10-10
ITMI20021921A1 (it) 2004-03-11
PL402323A1 (pl) 2013-04-02
KR101096918B1 (ko) 2011-12-22
SI2077264T1 (sl) 2013-03-29
DK2077264T3 (da) 2013-03-04
EP1537093B1 (de) 2008-06-11
RU2320652C2 (ru) 2008-03-27
DK2298754T3 (da) 2013-11-04
EP2281820A2 (de) 2011-02-09
PT1537093E (pt) 2008-09-02
IL214431A (en) 2014-05-28
NO332366B1 (no) 2012-09-03
AU2003267049A1 (en) 2004-04-30
WO2004024706A3 (en) 2004-07-08
PT2298754E (pt) 2013-11-07
EP2077264B1 (de) 2012-11-14
IL197815A (en) 2013-02-28
EP2264019A1 (de) 2010-12-22
JP4690039B2 (ja) 2011-06-01
PT2077264E (pt) 2013-01-29
IL214430A0 (en) 2011-09-27
EP2281820A3 (de) 2011-05-04
SI2264019T1 (sl) 2013-10-30
JP2010270145A (ja) 2010-12-02
DE60321577D1 (de) 2008-07-24
SI1537093T1 (sl) 2008-10-31
IL214432A (en) 2014-05-28
NO332367B1 (no) 2012-09-03
KR20050035540A (ko) 2005-04-18
EP1980557A3 (de) 2008-12-31
EP1980557A2 (de) 2008-10-15
SI2298754T1 (sl) 2013-11-29
CN1681799A (zh) 2005-10-12
EP1537093A2 (de) 2005-06-08
EP2264019B1 (de) 2013-07-24
ES2398324T3 (es) 2013-03-15
NO20110781L (no) 2005-05-10
NO20051774L (no) 2005-05-10
AU2003267049B2 (en) 2010-02-11
US20060122258A1 (en) 2006-06-08
IL214432A0 (en) 2011-09-27
CA2498277A1 (en) 2004-03-25
NO20110782L (no) 2005-05-10
EP2077264A3 (de) 2009-09-16
EP2298754A1 (de) 2011-03-23
US7498452B2 (en) 2009-03-03
NO332250B1 (no) 2012-08-06
ES2433580T3 (es) 2013-12-11
AU2003267049B8 (en) 2010-03-04
DK2264019T3 (da) 2013-10-28
PT2264019E (pt) 2013-10-28
PL375625A1 (en) 2005-12-12
JP2006503030A (ja) 2006-01-26

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