SG162817A1 - Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma - Google Patents

Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma

Info

Publication number
SG162817A1
SG162817A1 SG201004451-9A SG2010044519A SG162817A1 SG 162817 A1 SG162817 A1 SG 162817A1 SG 2010044519 A SG2010044519 A SG 2010044519A SG 162817 A1 SG162817 A1 SG 162817A1
Authority
SG
Singapore
Prior art keywords
compositions
expressed
methods
cancer cells
immune responses
Prior art date
Application number
SG201004451-9A
Other languages
English (en)
Inventor
Qiu Zhiyong
Adrian Bot
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of SG162817A1 publication Critical patent/SG162817A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG201004451-9A 2005-06-17 2006-06-16 Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma SG162817A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69157905P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
SG162817A1 true SG162817A1 (en) 2010-07-29

Family

ID=37325697

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201004451-9A SG162817A1 (en) 2005-06-17 2006-06-16 Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma

Country Status (14)

Country Link
US (2) US7999088B2 (pt)
EP (3) EP2385060A3 (pt)
JP (1) JP5416968B2 (pt)
KR (1) KR20080026181A (pt)
CN (1) CN101198620A (pt)
AU (1) AU2006259220C1 (pt)
BR (1) BRPI0611794A2 (pt)
CA (1) CA2612516C (pt)
ES (1) ES2413079T3 (pt)
IL (1) IL188113A (pt)
MX (1) MX2007015933A (pt)
NZ (1) NZ591908A (pt)
SG (1) SG162817A1 (pt)
WO (1) WO2006138567A2 (pt)

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CA2592972A1 (en) * 2004-12-29 2006-07-06 Mannkind Corporation Methods to bypass cd+4 cells in the induction of an immune response
WO2006138562A2 (en) * 2005-06-17 2006-12-28 Mannkind Corporation Epitope analogues
NZ564360A (en) * 2005-06-17 2011-03-31 Mannkind Corp Immunogenic product comprising a nucleic acid capable of expressing a PRAME epitope and a PSMA epitope and a peptide composition
SG162817A1 (en) 2005-06-17 2010-07-29 Mannkind Corp Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma
WO2008008541A2 (en) * 2006-07-14 2008-01-17 Mannkind Corporation Methods to elicit, enhance and sustain immune responses against mhc class-i restricted epitopes, for prophylactic or therapeutic purposes
CN106220721B (zh) 2007-03-26 2020-04-07 莱顿大学医学中心附属莱顿教学医院 Prame衍生的肽以及包括该肽的免疫原组合物
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RU2554821C1 (ru) * 2014-02-18 2015-06-27 Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Красноярский Государственный Медицинский Университет Имени Профессора В.Ф. Войно-Ясенецкого Министерства Здравоохранения Российской Федерации" Способ оценки степени локальной холодовой травмы в раннем реактивном периоде
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EP3400005A1 (en) * 2016-01-08 2018-11-14 Vaccibody AS Neoepitope rna cancer vaccine
CN106367406A (zh) * 2016-08-28 2017-02-01 苏州普罗达生物科技有限公司 Udp糖基转移酶免疫原多肽及其用途
CN106581668B (zh) * 2016-12-31 2020-03-24 广州姿生生物科技有限公司 一种抗原表位肽组合物及其应用
CN112686128B (zh) * 2020-12-28 2022-10-14 南京览众智能科技有限公司 基于机器学习的教室课桌检测方法
JP2024518378A (ja) 2021-05-05 2024-05-01 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｐｒａｍｅに特異的に結合する抗原結合タンパク質

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Also Published As

Publication number Publication date
AU2006259220B2 (en) 2012-10-11
EP1896494B1 (en) 2013-04-03
CA2612516C (en) 2015-03-24
IL188113A (en) 2015-03-31
IL188113A0 (en) 2008-03-20
AU2006259220C1 (en) 2013-05-16
KR20080026181A (ko) 2008-03-24
CA2612516A1 (en) 2006-12-28
US7999088B2 (en) 2011-08-16
US20110269949A1 (en) 2011-11-03
WO2006138567A2 (en) 2006-12-28
US20070004662A1 (en) 2007-01-04
JP5416968B2 (ja) 2014-02-12
MX2007015933A (es) 2008-04-21
BRPI0611794A2 (pt) 2010-09-28
ES2413079T3 (es) 2013-07-15
CN101198620A (zh) 2008-06-11
EP2385060A2 (en) 2011-11-09
EP2385060A3 (en) 2012-02-15
EP1896494A2 (en) 2008-03-12
EP2385059A2 (en) 2011-11-09
EP2385059A3 (en) 2012-02-15
AU2006259220A1 (en) 2006-12-28
US8674081B2 (en) 2014-03-18
WO2006138567A3 (en) 2007-02-15
NZ591908A (en) 2012-09-28
JP2008543315A (ja) 2008-12-04

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