SG144689A1 - Embryonic stem cells and neural progenitor cells derived therefrom - Google Patents

Embryonic stem cells and neural progenitor cells derived therefrom

Info

Publication number
SG144689A1
SG144689A1 SG200206039-0A SG2002060390A SG144689A1 SG 144689 A1 SG144689 A1 SG 144689A1 SG 2002060390 A SG2002060390 A SG 2002060390A SG 144689 A1 SG144689 A1 SG 144689A1
Authority
SG
Singapore
Prior art keywords
cells
neural
differentiation
embryonic stem
progenitor cells
Prior art date
Application number
SG200206039-0A
Other languages
English (en)
Inventor
Martin Frederick Pera
Tamir Ben Hur
Benjamin Eithan Reubinoff
Original Assignee
Univ Singapore
Univ Monash
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore, Univ Monash, Hadasit Med Res Service filed Critical Univ Singapore
Publication of SG144689A1 publication Critical patent/SG144689A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/395—Thyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90—Polysaccharides
    • C12N2501/91—Heparin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG200206039-0A 2001-10-04 2002-10-04 Embryonic stem cells and neural progenitor cells derived therefrom SG144689A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/970,543 US7011828B2 (en) 2000-03-14 2001-10-04 Implanting neural progenitor cells derived for human embryonic stem cells

Publications (1)

Publication Number Publication Date
SG144689A1 true SG144689A1 (en) 2008-08-28

Family

ID=25517110

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200206039-0A SG144689A1 (en) 2001-10-04 2002-10-04 Embryonic stem cells and neural progenitor cells derived therefrom

Country Status (7)

Country Link
US (1) US7011828B2 (fr)
EP (1) EP1302536A3 (fr)
JP (2) JP2004248507A (fr)
AU (1) AU2002301347B2 (fr)
CA (1) CA2406610A1 (fr)
IL (1) IL152106A0 (fr)
SG (1) SG144689A1 (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2403000C (fr) * 2000-03-14 2015-06-23 Es Cell International Pte Ltd Cellules embryonnaires et cellules souches neuronales derivees de celles-ci
US20080268054A1 (en) * 2000-12-04 2008-10-30 Eugene Bell Dermal derived human stem cells and compositions and methods thereof
US7566101B2 (en) * 2002-07-15 2009-07-28 Hennessy Industries, Inc. Vehicle wheel balance weights
US20070020608A1 (en) * 2003-05-08 2007-01-25 Peter Eriksson Method for the generation of neural progenitor cells
US7638328B2 (en) * 2003-05-08 2009-12-29 Cellartis Ab Method for efficient transfer of human blastocyst-derived stem cells (hBS cells) from a feeder-supported to a feeder-free culture system, long-term propagation of hBS cells under feeder-free conditions and use of cultured hBS cells for applications in myocardial regeneration
JP4389037B2 (ja) * 2003-06-03 2009-12-24 独立行政法人理化学研究所 Ｅｓ細胞の電気パルス処理によって得られた神経細胞
GB2427876B (en) * 2004-04-09 2009-02-18 Ronald S Goldstein Methods for generating neuronal cells from human embryonic stem cells and uses thereof
JP2007532128A (ja) * 2004-04-13 2007-11-15 カレッジ オブ メディスン ポーチョン シーエイチエー ユニバーシティ インダストリー−アカデミック コーポレーション ファウンデーション 生殖幹細胞の単離、増殖および分化のインビトロ方法
US7622108B2 (en) 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
ATE506431T1 (de) 2004-04-23 2011-05-15 Bioe Llc Mehrfachlinien-vorläuferzellen
JP2006149329A (ja) * 2004-12-01 2006-06-15 Univ Of Tokyo 繊毛上皮細胞調製方法
JP2006204292A (ja) * 2004-12-27 2006-08-10 Asahi Kasei Corp ヒト胚性幹細胞分化抑制剤
US8178349B2 (en) * 2005-02-09 2012-05-15 Burnham Institute For Medical Research Homogeneous neural precursor cells
WO2006101834A1 (fr) * 2005-03-17 2006-09-28 Stratatech Corporation Substituts de la peau a purete amelioree
WO2006110806A2 (fr) * 2005-04-12 2006-10-19 The Trustees Of The University Of Pennsylvania Cellules souches adultes multipotentes
KR20080056182A (ko) * 2005-09-02 2008-06-20 에이전시 포 사이언스, 테크놀로지 앤드 리서치 간엽 줄기 세포의 유도 방법
ITNA20060017A1 (it) * 2006-02-20 2007-08-21 Aquino Riccardo D Tecnica di prelievo e selezione di un una popolazione di cellule staminali di tipo embrionale da tessuti follicolari peridentari di uomo adulto.
EP2019858B1 (fr) 2006-04-17 2012-06-13 BioE LLC Différenciation des cellules progénitrices à lignées multiples en cellules épithéliales respiratoires
US20080003681A1 (en) * 2006-06-28 2008-01-03 Mahalaxmi Gita Bangera Methods for altering cellular susceptibility to infection
GB0622394D0 (en) 2006-11-09 2006-12-20 Univ Cambridge Tech Differentiation of pluripotent cells
CN101835479A (zh) * 2007-07-25 2010-09-15 佰欧益有限公司 多系祖细胞分化为软骨细胞
US8338176B2 (en) * 2007-07-30 2012-12-25 The Board Of Trustees Of The Leland Stanford Junior University Derivation of neural stem cells from embryonic stem cells
WO2009058451A2 (fr) * 2007-08-02 2009-05-07 California Stem Cell, Inc. Cellules progénitrices neuronales et procédés de dérivation et de purification de cellules progénitrices neuronales de cellules souches embryonnaires
KR101175175B1 (ko) * 2008-07-28 2012-08-20 서울대학교병원 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포
US8642334B2 (en) 2009-02-17 2014-02-04 Memorial Sloan Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
JP5783504B2 (ja) * 2009-03-30 2015-09-24 国立研究開発法人国立環境研究所 胎生プログラミングに対する影響を評価するための方法
US20110052549A1 (en) * 2009-08-27 2011-03-03 The Regents Of The University Of California Cell culture device to differentiate stem cells in a specific orientation
JP2013506681A (ja) * 2009-10-02 2013-02-28 バクスター・インターナショナル・インコーポレイテッド 腎損傷の処置における使用のための造血幹細胞
WO2011074690A1 (fr) 2009-12-14 2011-06-23 Kyoto University Composition pharmaceutique destinée à la prévention ou au traitement de la sclérose latérale amyotrophique
ES2725549T3 (es) 2010-07-12 2019-09-24 Univ Southern California Sustrato biocompatible para facilitar las interconexiones entre células madre y tejidos diana y métodos para implantarlo
CA2815223A1 (fr) * 2010-10-26 2012-07-19 Case Western Reserve University Procedes de differenciation pour la production de populations de cellules gliales
US9487752B2 (en) * 2011-03-30 2016-11-08 Cellular Dynamics International, Inc. Priming of pluripotent stem cells for neural differentiation
US8877489B2 (en) 2011-12-05 2014-11-04 California Institute Of Technology Ultrathin parylene-C semipermeable membranes for biomedical applications
US10478206B2 (en) 2011-04-29 2019-11-19 University Of Southern California Instruments and methods for the implantation of cell-seeded substrates
ES2779453T3 (es) 2011-11-04 2020-08-17 Memorial Sloan Kettering Cancer Center Neuronas de dopamina (DA) del mesencéfalo para injerto
US9248013B2 (en) 2011-12-05 2016-02-02 California Institute Of Technology 3-Dimensional parylene scaffold cage
US20130216495A1 (en) 2012-02-21 2013-08-22 Baxter Healthcare Sa Pharmaceutical composition comprising cd34+ cells
JP6335117B2 (ja) 2012-03-21 2018-05-30 国立大学法人京都大学 アルツハイマー病の治療薬および／または予防薬のスクリーニング方法
KR102073111B1 (ko) * 2012-10-16 2020-02-04 메르츠 파마 게엠베하 운트 코. 카가아 신경독소 폴리펩티드의 생물학적 활성의 결정을 위한 세포 테스트 시스템
AU2014236150B2 (en) 2013-03-14 2019-10-31 The Regents Of The University Of California In vitro production of medial ganglionic eminence precursor cells
EP2989198A4 (fr) 2013-04-26 2016-10-26 Sloan Kettering Inst Cancer Interneurones corticaux et autres cellules neuronales produits par la différentiation dirigée de cellules pluripotentes et multipotentes
CN105940101A (zh) 2013-11-21 2016-09-14 纪念斯隆-凯特琳癌症中心 由人多能干细胞特化功能性颅基板衍生物
JP6329468B2 (ja) * 2014-09-16 2018-05-23 三菱製紙株式会社 線維芽細胞のガラス化凍結保存方法
WO2016101017A1 (fr) 2014-12-24 2016-06-30 Neuorphan Pty Ltd Améliorations de procédés de culture d'oligodendrocytes et de méthodes de traitement de troubles neurodégénératifs à l'aide d'hormones thyroïdiennes ou analogues

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000027995A1 (fr) * 1998-11-09 2000-05-18 Monash University Cellules souches embryonnaires
WO2001068815A1 (fr) * 2000-03-14 2001-09-20 Es Cell International Pte Ltd Cellules embryonnaires et cellules souches neuronales derivees de celles-ci
WO2001088104A2 (fr) * 2000-05-17 2001-11-22 Geron Corporation Populations de progeniteurs neuronaux

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968829A (en) * 1997-09-05 1999-10-19 Cytotherapeutics, Inc. Human CNS neural stem cells
DE19756864C5 (de) 1997-12-19 2014-07-10 Oliver Brüstle Neurale Vorläuferzellen, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von neuralen Defekten
AU779694B2 (en) * 2000-03-14 2005-02-03 Es Cell International Pte Ltd Embryonic stem cells and neural progenitor cells derived therefrom

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000027995A1 (fr) * 1998-11-09 2000-05-18 Monash University Cellules souches embryonnaires
WO2001068815A1 (fr) * 2000-03-14 2001-09-20 Es Cell International Pte Ltd Cellules embryonnaires et cellules souches neuronales derivees de celles-ci
WO2001088104A2 (fr) * 2000-05-17 2001-11-22 Geron Corporation Populations de progeniteurs neuronaux

Also Published As

Publication number Publication date
JP2004248507A (ja) 2004-09-09
CA2406610A1 (fr) 2003-04-04
EP1302536A3 (fr) 2004-03-24
IL152106A0 (en) 2003-07-31
EP1302536A2 (fr) 2003-04-16
US7011828B2 (en) 2006-03-14
AU2002301347B2 (en) 2008-04-03
US20020164308A1 (en) 2002-11-07
JP2008201792A (ja) 2008-09-04

Similar Documents

Publication Publication Date Title
SG144689A1 (en) Embryonic stem cells and neural progenitor cells derived therefrom
WO2003065999A3 (fr) Lignees de cellules qui ont prolifere et leurs utilisations
WO2006050330A3 (fr) Plaquettes de cellules souches
WO2003004605A3 (fr) Osteoblastes et cellules mesenchymateuses provenant de cellule souche embryonnaire humaine
GB2428044A (en) Method of forming mesenchymal stem cells from embryonic stem cells
WO2006044204A3 (fr) Progeniteurs neuronaux obtenus par culture de cellules souches embryonnaires humaines sans cellules nourricieres
DE50112855D1 (de) Verfahren zur Herstellung von Knorpelimplantaten mittels in vitro gezüchteter Chondrozyten
WO2009137624A3 (fr) Cellules formant des colonies hémangioblastiques et cellules hémangioblastiques non transplantables
AU2002258477A1 (en) Use of rna interference for the creation of lineage specific es and other undifferentiated cells and production of differentiated cells in vitro by co-culture
MX2012000455A (es) Composiciones de matriz extra-celular y medio acondicionado a partir de celulas cultivadas bajo condiciones hipoxicas.
WO2006017134A3 (fr) Cellules mesendodermiques et cellules de ligne pre-primitive
BRPI0619579B8 (pt) Métodos para aumentar a expectativa de vida replicativa e/ou estabilidade de uma célula produtora de anticorpo, para expressar um gene de uma célula b codificando a cadeia pesada de ig e/ou cadeia leve de ig, para produzir linhagem de células b, para obter anticorpos, e, método ex vivo para produzir anticorpos capazes de especificamente ligar um antígeno de interesse
HK1118577A1 (en) Rnai expression constructs rnai
HUP0500477A2 (hu) Eljárások és készítmények embrionális és felnőttkori őssejtek támogatására stromasejtek alkalmazásával
ATE553186T1 (de) Bandscheibenreparatur und verfahren dafür
WO2007080590A3 (fr) Progéniteurs de tissus conjonctifs obtenus à partir de cellules souches embryonnaires humaines à des fins de génie tissulaire
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
WO2002070729A3 (fr) Substituts de peau ameliores et utilisations correspondantes
WO2004113513A3 (fr) Procedes et compositions pour moduler la croissance et la differentiation des cellules souches
NO20090598L (no) 6,9-disubstituerte purinderivater og deres anvendelse for behandling av hud
WO2004011603A3 (fr) Cardiomyocytes fonctionnels provenant de cellules souches embryonnaires humaines
DE60041821D1 (de) Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen
ATE481477T1 (de) Endothelvorläuferzellen und verfahren zur verwendung davon
Muffat et al. CNS disease models with human pluripotent stem cells in the CRISPR age
WO2004007683A3 (fr) Reprogrammation cellulaire dans un hydrogel peptidique et utilisations associees