SG11202011883RA - Pharmaceutical combination, composition, and combination formulation containing glucokinase activator and ppar receptor activator, and preparation methods and uses thereof - Google Patents
Pharmaceutical combination, composition, and combination formulation containing glucokinase activator and ppar receptor activator, and preparation methods and uses thereofInfo
- Publication number
- SG11202011883RA SG11202011883RA SG11202011883RA SG11202011883RA SG11202011883RA SG 11202011883R A SG11202011883R A SG 11202011883RA SG 11202011883R A SG11202011883R A SG 11202011883RA SG 11202011883R A SG11202011883R A SG 11202011883RA SG 11202011883R A SG11202011883R A SG 11202011883RA
- Authority
- SG
- Singapore
- Prior art keywords
- activator
- combination
- composition
- preparation methods
- formulation containing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 2
- 101150014691 PPARA gene Proteins 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 229940124828 glucokinase activator Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 108091006084 receptor activators Proteins 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
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- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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SG11202011886TA SG11202011886TA (en) | 2018-05-31 | 2019-05-28 | PHARMACEUTICAL COMBINATION, COMPOSITION AND FORMULATION CONTAINING GLUCOKINASE ACTIVATOR AND a-GLUCOSIDASE INHIBITOR, PREPARATION METHODS THEREFOR AND USES THEREOF |
SG11202011881PA SG11202011881PA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition and combination formulation comprising glucokinase activator and dpp-iv inhibitor, and preparation method and use thereof |
SG11202011888VA SG11202011888VA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition and compound preparation containing glucokinase activator and k-atp channel blocker, preparation method therefor and use thereof |
SG11202011884QA SG11202011884QA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition, and combination preparation comprising glucokinase activator and sglt-2 inhibitor and preparation methods and uses thereof |
SG11202011883RA SG11202011883RA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition, and combination formulation containing glucokinase activator and ppar receptor activator, and preparation methods and uses thereof |
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SG11202011886TA SG11202011886TA (en) | 2018-05-31 | 2019-05-28 | PHARMACEUTICAL COMBINATION, COMPOSITION AND FORMULATION CONTAINING GLUCOKINASE ACTIVATOR AND a-GLUCOSIDASE INHIBITOR, PREPARATION METHODS THEREFOR AND USES THEREOF |
SG11202011881PA SG11202011881PA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition and combination formulation comprising glucokinase activator and dpp-iv inhibitor, and preparation method and use thereof |
SG11202011888VA SG11202011888VA (en) | 2018-05-31 | 2019-05-28 | Pharmaceutical combination, composition and compound preparation containing glucokinase activator and k-atp channel blocker, preparation method therefor and use thereof |
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US11813274B2 (en) * | 2020-04-22 | 2023-11-14 | Hua Medicine (Shanghai) Ltd. | Treating untreated or treatment-resistant diabetes with glucokinase activator and sodium-glucose cotransporter-2 inhibitor |
WO2021212360A1 (en) * | 2020-04-22 | 2021-10-28 | Hua Medicine (Shanghai) Ltd. | Treating untreated or treatment-resistant diabetes with glucokinase activator and sodium-glucose cotransporter-2 inhibitor |
CA3185831A1 (en) * | 2020-06-04 | 2021-12-09 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
WO2021243646A1 (en) * | 2020-06-04 | 2021-12-09 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with hepatic impairment |
US11857536B2 (en) | 2020-06-04 | 2024-01-02 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
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