SG11202011884QA - Pharmaceutical combination, composition, and combination preparation comprising glucokinase activator and sglt-2 inhibitor and preparation methods and uses thereof - Google Patents

Pharmaceutical combination, composition, and combination preparation comprising glucokinase activator and sglt-2 inhibitor and preparation methods and uses thereof

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Publication number
SG11202011884QA
SG11202011884QA SG11202011884QA SG11202011884QA SG11202011884QA SG 11202011884Q A SG11202011884Q A SG 11202011884QA SG 11202011884Q A SG11202011884Q A SG 11202011884QA SG 11202011884Q A SG11202011884Q A SG 11202011884QA SG 11202011884Q A SG11202011884Q A SG 11202011884QA
Authority
SG
Singapore
Prior art keywords
combination
preparation
sglt
inhibitor
composition
Prior art date
Application number
SG11202011884QA
Inventor
Li Chen
Yongguo Li
Gaosen Wang
Huisheng Gao
Original Assignee
Hua Medicine Shanghai Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hua Medicine Shanghai Ltd filed Critical Hua Medicine Shanghai Ltd
Publication of SG11202011884QA publication Critical patent/SG11202011884QA/en

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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TWI764000B (en) 2022-05-11
WO2019228363A1 (en) 2019-12-05
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