SG11202011094PA - Method for preparing oligonucleic acid compound - Google Patents

Method for preparing oligonucleic acid compound

Info

Publication number
SG11202011094PA
SG11202011094PA SG11202011094PA SG11202011094PA SG11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA
Authority
SG
Singapore
Prior art keywords
preparing
acid compound
oligonucleic acid
oligonucleic
compound
Prior art date
Application number
SG11202011094PA
Other languages
English (en)
Inventor
Yutaro Kotobuki
Fumiya URABE
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of SG11202011094PA publication Critical patent/SG11202011094PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
SG11202011094PA 2018-05-10 2019-05-10 Method for preparing oligonucleic acid compound SG11202011094PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018091231 2018-05-10
PCT/JP2019/018828 WO2019216433A1 (ja) 2018-05-10 2019-05-10 オリゴ核酸化合物の製造方法

Publications (1)

Publication Number Publication Date
SG11202011094PA true SG11202011094PA (en) 2020-12-30

Family

ID=68468137

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011094PA SG11202011094PA (en) 2018-05-10 2019-05-10 Method for preparing oligonucleic acid compound

Country Status (9)

Country Link
US (1) US11560401B2 (zh)
EP (1) EP3792269A4 (zh)
JP (1) JP7394749B2 (zh)
KR (1) KR20210008055A (zh)
CN (1) CN112384520A (zh)
AU (1) AU2019266768B2 (zh)
CA (1) CA3099778A1 (zh)
SG (1) SG11202011094PA (zh)
WO (1) WO2019216433A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109851593B (zh) * 2019-02-01 2021-04-16 沈阳药科大学 基于淋巴介导转运的甘油三酯前药及其制备方法
WO2021095874A1 (ja) * 2019-11-13 2021-05-20 日本新薬株式会社 オリゴ核酸化合物の製造方法
KR20240004559A (ko) * 2021-04-28 2024-01-11 니뽄 신야쿠 가부시키가이샤 올리고 핵산 화합물의 제조 방법
WO2023127918A1 (ja) * 2021-12-27 2023-07-06 日本新薬株式会社 オリゴ核酸化合物の製造方法

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* Cited by examiner, † Cited by third party
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FR2130844A5 (zh) 1971-03-23 1972-11-10 Commissariat Energie Atomique
JPS5668388A (en) 1979-11-10 1981-06-09 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of cell body of spirulina algae
DE69033986T2 (de) 1989-12-20 2003-03-13 Antivirals Inc Ungeladene, auf Morpholin basierende Polymere mit Chiralen, Phosphor enthaltenden Brücken zwischen den Untereinheiten
WO2003106468A1 (en) 2002-06-13 2003-12-24 Rhodia, Inc. Process of making phosphordiamidite compounds
US8067571B2 (en) * 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
JP2010505741A (ja) * 2006-05-10 2010-02-25 エイブイアイ バイオファーマ, インコーポレイテッド カチオン性のサブユニット間結合を有するオリゴヌクレオチドアナログ
KR100886139B1 (ko) 2007-11-13 2009-02-27 주식회사 삼천리제약 올리고뉴클레오타이드의 제조방법
WO2009064471A1 (en) 2007-11-15 2009-05-22 Avi Biopharma, Inc. Method of synthesis of morpholino oligomers
JP5548852B2 (ja) 2009-05-29 2014-07-16 国立大学法人東京農工大学 疎水性基結合ヌクレオシド、疎水性基結合ヌクレオシド溶液、及び疎水性基結合オリゴヌクレオチド合成方法
DK2623507T3 (da) 2010-09-30 2017-01-02 Nippon Shinyaku Co Ltd Morpholinonukleinsyrederivat
US9029528B2 (en) 2011-05-17 2015-05-12 Ajinomoto Co., Inc. Solution-based method of making oligonucleotides via phosphoramidite coupling
KR102271212B1 (ko) 2011-11-18 2021-07-01 사렙타 쎄러퓨틱스, 인코퍼레이티드 기능적으로-변형된 올리고뉴클레오티드 및 이의 서브유니트
WO2013082548A1 (en) 2011-11-30 2013-06-06 Sarepta Therapeutics, Inc. Oligonucleotides for treating expanded repeat diseases
WO2013122236A1 (ja) 2012-02-17 2013-08-22 味の素株式会社 塩基部保護オリゴヌクレオチド
CN104768964B (zh) * 2012-09-21 2017-03-29 国立大学法人大阪大学 具有胍桥的人工核苷和寡核苷酸
CN104918949B (zh) 2012-11-14 2017-10-10 武田药品工业株式会社 核酸的液相合成方法
JP6477464B2 (ja) * 2013-05-24 2019-03-06 味の素株式会社 モルフォリノオリゴヌクレオチドの製造方法
CN106795186B (zh) * 2014-10-14 2021-03-02 味之素株式会社 吗啉代寡核苷酸的制备方法
EP3266792B1 (en) 2015-03-04 2020-12-30 Jitsubo Co., Ltd. Peptide synthesis method

Also Published As

Publication number Publication date
CN112384520A (zh) 2021-02-19
AU2019266768A1 (en) 2020-12-17
US20210261596A1 (en) 2021-08-26
JP7394749B2 (ja) 2023-12-08
CA3099778A1 (en) 2019-11-14
EP3792269A4 (en) 2022-06-22
WO2019216433A1 (ja) 2019-11-14
US11560401B2 (en) 2023-01-24
EP3792269A1 (en) 2021-03-17
AU2019266768B2 (en) 2024-02-29
KR20210008055A (ko) 2021-01-20
JPWO2019216433A1 (ja) 2021-05-27

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