SG11202003762VA - Synthesis of boronate ester derivatives and uses thereof - Google Patents

Synthesis of boronate ester derivatives and uses thereof

Info

Publication number
SG11202003762VA
SG11202003762VA SG11202003762VA SG11202003762VA SG11202003762VA SG 11202003762V A SG11202003762V A SG 11202003762VA SG 11202003762V A SG11202003762V A SG 11202003762VA SG 11202003762V A SG11202003762V A SG 11202003762VA SG 11202003762V A SG11202003762V A SG 11202003762VA
Authority
SG
Singapore
Prior art keywords
synthesis
ester derivatives
boronate ester
boronate
derivatives
Prior art date
Application number
SG11202003762VA
Other languages
English (en)
Inventor
Serge Boyer
Scott Hecker
Gerardus Verzijl
Petrus Hermsen
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of SG11202003762VA publication Critical patent/SG11202003762VA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/46Ruthenium, rhodium, osmium or iridium
    • B01J23/462Ruthenium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/04Esters of boric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
SG11202003762VA 2017-11-01 2018-10-30 Synthesis of boronate ester derivatives and uses thereof SG11202003762VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762580343P 2017-11-01 2017-11-01
PCT/US2018/058143 WO2019089542A1 (en) 2017-11-01 2018-10-30 Synthesis of boronate ester derivatives and uses thereof

Publications (1)

Publication Number Publication Date
SG11202003762VA true SG11202003762VA (en) 2020-05-28

Family

ID=66245250

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003762VA SG11202003762VA (en) 2017-11-01 2018-10-30 Synthesis of boronate ester derivatives and uses thereof

Country Status (15)

Country Link
US (2) US20200308197A1 (ar)
EP (1) EP3704130A4 (ar)
JP (1) JP7480050B2 (ar)
KR (1) KR20200076730A (ar)
CN (1) CN111556872B (ar)
AU (1) AU2018360502B2 (ar)
BR (1) BR112020008498A2 (ar)
CA (1) CA3080763A1 (ar)
CL (1) CL2020001143A1 (ar)
CO (1) CO2020006299A2 (ar)
JO (1) JOP20200101A1 (ar)
MX (2) MX2020004425A (ar)
PH (1) PH12020550544A1 (ar)
SG (1) SG11202003762VA (ar)
WO (1) WO2019089542A1 (ar)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783443A (en) 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
DE10119274A1 (de) * 2001-04-20 2002-10-31 Juelich Enzyme Products Gmbh Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen
EP1386901B1 (en) * 2002-07-30 2015-07-01 Takasago International Corporation Method for producing an optically active beta-amino acid
DE102004022397A1 (de) * 2004-05-06 2005-12-01 Consortium für elektrochemische Industrie GmbH Chirale C2-symmetrische Biphenyle, deren Herstellung sowie Metallkomplexe enthaltend diese Liganden und deren Verwendung als Katalysatoren in chirogenen Synthesen
WO2007034909A1 (ja) * 2005-09-22 2007-03-29 Kaneka Corporation (3r,5r)-7-アミノ-3,5-ジヒドロキシヘプタン酸誘導体の製造法
BR112013003045B1 (pt) * 2010-08-10 2021-08-31 Rempex Pharmaceuticals, Inc. Composto e respectivo uso, composição farmacêutica, recipiente estéril e método para preparar composição farmacêutica para administração
WO2013056163A1 (en) * 2011-10-14 2013-04-18 The Regents Of The University Of California Beta-lactamase inhibitors
WO2013122888A2 (en) * 2012-02-15 2013-08-22 Rempex Pharmaceuticals, Inc. Methods of treating bacterial infections
US9422314B2 (en) * 2012-12-07 2016-08-23 VenatoRx Pharmaceuticals, Inc. Beta-lactamase inhibitors
EP4356736A2 (en) * 2014-05-05 2024-04-24 Melinta Therapeutics, Inc. Synthesis of boronate salts

Also Published As

Publication number Publication date
AU2018360502A1 (en) 2020-06-04
CL2020001143A1 (es) 2020-10-30
CA3080763A1 (en) 2019-05-09
CN111556872A (zh) 2020-08-18
MX2020004425A (es) 2020-08-06
KR20200076730A (ko) 2020-06-29
WO2019089542A1 (en) 2019-05-09
EP3704130A4 (en) 2021-07-07
PH12020550544A1 (en) 2021-03-22
EP3704130A1 (en) 2020-09-09
BR112020008498A2 (pt) 2020-10-20
CO2020006299A2 (es) 2020-06-09
AU2018360502B2 (en) 2024-05-02
JP2021501205A (ja) 2021-01-14
JP7480050B2 (ja) 2024-05-09
CN111556872B (zh) 2024-05-10
JOP20200101A1 (ar) 2022-10-30
US20200308197A1 (en) 2020-10-01
MX2023000529A (es) 2023-02-13
US20190127396A1 (en) 2019-05-02

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