SG11202000893QA - Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease - Google Patents

Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Info

Publication number
SG11202000893QA
SG11202000893QA SG11202000893QA SG11202000893QA SG11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA
Authority
SG
Singapore
Prior art keywords
treatment
nitric oxide
lung disease
pulmonary hypertension
hypertension associated
Prior art date
Application number
SG11202000893QA
Other languages
English (en)
Inventor
Deborah Quinn
Parag Shah
Original Assignee
Bellerophon Pulse Tech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bellerophon Pulse Tech Llc filed Critical Bellerophon Pulse Tech Llc
Publication of SG11202000893QA publication Critical patent/SG11202000893QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022Control means therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • A61M2202/0275Nitric oxide [NO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1039Lungs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system
    • A61M2210/125Heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/30Blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/40Respiratory characteristics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202000893QA 2017-08-30 2018-08-29 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease SG11202000893QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762552022P 2017-08-30 2017-08-30
US201762611325P 2017-12-28 2017-12-28
PCT/US2018/048526 WO2019046415A1 (en) 2017-08-30 2018-08-29 USE OF INHALED NITRIC OXIDE FOR THE TREATMENT OF PULMONARY HYPERTENSION ASSOCIATED WITH PULMONARY DISEASE

Publications (1)

Publication Number Publication Date
SG11202000893QA true SG11202000893QA (en) 2020-02-27

Family

ID=65526008

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000893QA SG11202000893QA (en) 2017-08-30 2018-08-29 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Country Status (14)

Country Link
US (2) US20200188319A1 (es)
EP (2) EP3675840A4 (es)
JP (3) JP2020532521A (es)
KR (1) KR20200083443A (es)
CN (2) CN111315283A (es)
AU (2) AU2018324004A1 (es)
BR (1) BR112020004205A2 (es)
CA (2) CA3073949A1 (es)
IL (2) IL272308A (es)
MX (1) MX2020002194A (es)
PH (1) PH12020500197A1 (es)
SG (1) SG11202000893QA (es)
TW (2) TW201912151A (es)
WO (2) WO2019046415A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220137155A (ko) 2017-02-27 2022-10-11 써드 폴, 아이엔씨. 산화질소의 이동식 생성을 위한 시스템 및 방법
JP6704094B2 (ja) 2017-02-27 2020-06-03 サード ポール, インコーポレイテッドThird Pole, Inc. 酸化窒素を生成するためのシステムおよび方法
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
EP3969415A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. ELECTRODES FOR NITRIC OXIDE GENERATION
WO2020232419A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Systems and methods for generating nitric oxide
JP2023512444A (ja) 2020-01-11 2023-03-27 サード ポール,インコーポレイテッド 湿度制御を用いた酸化窒素生成のためのシステムおよび方法
US20210345952A1 (en) * 2020-05-06 2021-11-11 Janssen Pharmaceuticals, Inc. Controlling operation of drug administration devices using surgical hubs
IL298659A (en) * 2020-05-29 2023-01-01 Bellerophon Therapeutics A method for the pulsatile administration of a gaseous drug
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008073928A1 (en) * 2006-12-12 2008-06-19 Gilead Colorado, Inc. Composition for treating a pulmonary hypertension
WO2009048521A1 (en) * 2007-10-11 2009-04-16 Duke University Potentiating the effect of compound comprising nitric oxide
CA2714272C (en) * 2008-01-31 2016-06-28 Vanderbilt University Therapeutic treatment for lung conditions
AU2009202685B1 (en) * 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
EP2645860A4 (en) * 2010-12-03 2014-07-09 Geno Llc NITROGEN OXIDE TREATMENTS
CA2874842C (en) * 2012-05-31 2021-01-26 Ino Therapeutics Llc Methods of administering nitric oxide to arterial or arterialized blood
WO2014089188A1 (en) * 2012-12-04 2014-06-12 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US9795756B2 (en) * 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
CA2936490C (en) * 2014-01-10 2022-10-04 Ino Therapeutics Llc Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
WO2015148169A1 (en) * 2014-03-28 2015-10-01 Shape Medical Systems, Inc. Pattern recognition system for quantifying the likelihood of the contribution of multiple possible forms of chronic disease to patient reported dyspnea
US20170165294A1 (en) * 2015-12-11 2017-06-15 Geno Llc Method and apparatus for administering gases including nitric oxide to address fibrosis
US20170182088A1 (en) * 2015-12-28 2017-06-29 Geno Llc Method and apparatus for administering nitric oxide with supplemental drugs
KR20190014493A (ko) * 2016-02-12 2019-02-12 말린크로트 하스피탈 프로덕츠 아이피 리미티드 좌심실 보조 장치에 의한 흡인성 일산화질소의 사용 및 모니터링

Also Published As

Publication number Publication date
EP3675719A4 (en) 2021-07-14
TW201919590A (zh) 2019-06-01
JP2023100985A (ja) 2023-07-19
EP3675719A1 (en) 2020-07-08
AU2018323547A1 (en) 2020-02-13
PH12020500197A1 (en) 2020-10-19
JP2020532521A (ja) 2020-11-12
TW201912151A (zh) 2019-04-01
CA3073948A1 (en) 2019-03-07
BR112020004205A2 (pt) 2020-09-01
CN111372577A (zh) 2020-07-03
US20200188319A1 (en) 2020-06-18
CN111315283A (zh) 2020-06-19
MX2020002194A (es) 2020-11-24
EP3675840A4 (en) 2021-05-12
EP3675840A1 (en) 2020-07-08
CA3073949A1 (en) 2019-03-07
US20200360647A1 (en) 2020-11-19
IL272314A (en) 2020-03-31
AU2018324004A1 (en) 2020-02-13
JP2020532531A (ja) 2020-11-12
KR20200083443A (ko) 2020-07-08
WO2019046415A1 (en) 2019-03-07
WO2019046413A1 (en) 2019-03-07
IL272308A (en) 2020-03-31

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