SG11202000893QA - Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease - Google Patents

Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Info

Publication number
SG11202000893QA
SG11202000893QA SG11202000893QA SG11202000893QA SG11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA SG 11202000893Q A SG11202000893Q A SG 11202000893QA
Authority
SG
Singapore
Prior art keywords
treatment
nitric oxide
lung disease
pulmonary hypertension
hypertension associated
Prior art date
Application number
SG11202000893QA
Inventor
Deborah Quinn
Parag Shah
Original Assignee
Bellerophon Pulse Tech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bellerophon Pulse Tech Llc filed Critical Bellerophon Pulse Tech Llc
Publication of SG11202000893QA publication Critical patent/SG11202000893QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022Control means therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • A61M2202/0275Nitric oxide [NO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1039Lungs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system
    • A61M2210/125Heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/30Blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/40Respiratory characteristics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202000893QA 2017-08-30 2018-08-29 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease SG11202000893QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762552022P 2017-08-30 2017-08-30
US201762611325P 2017-12-28 2017-12-28
PCT/US2018/048526 WO2019046415A1 (en) 2017-08-30 2018-08-29 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Publications (1)

Publication Number Publication Date
SG11202000893QA true SG11202000893QA (en) 2020-02-27

Family

ID=65526008

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000893QA SG11202000893QA (en) 2017-08-30 2018-08-29 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Country Status (14)

Country Link
US (2) US20200360647A1 (en)
EP (2) EP3675840A4 (en)
JP (3) JP2020532531A (en)
KR (1) KR20200083443A (en)
CN (2) CN111315283A (en)
AU (2) AU2018323547A1 (en)
BR (1) BR112020004205A2 (en)
CA (2) CA3073948A1 (en)
IL (2) IL272308A (en)
MX (1) MX2020002194A (en)
PH (1) PH12020500197A1 (en)
SG (1) SG11202000893QA (en)
TW (2) TW201912151A (en)
WO (2) WO2019046413A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020010523A (en) 2017-02-27 2021-02-09 Third Pole Inc Systems and methods for generating nitric oxide.
CN113456966A (en) 2017-02-27 2021-10-01 第三极股份有限公司 System and method for mobile generation of nitric oxide
CN113620263A (en) 2017-02-27 2021-11-09 第三极股份有限公司 System and method for generating nitric oxide
EP3969415A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. Electrodes for nitric oxide generation
JP2022532654A (en) 2019-05-15 2022-07-15 サード ポール,インコーポレイテッド Systems and methods for producing nitric oxide
CN115151183A (en) 2020-01-11 2022-10-04 第三极股份有限公司 System and method for nitric oxide generation with humidity control
US20210345952A1 (en) * 2020-05-06 2021-11-11 Janssen Pharmaceuticals, Inc. Controlling operation of drug administration devices using surgical hubs
CN116096446A (en) * 2020-05-29 2023-05-09 背勒丰治疗公司 Method for pulsed delivery of gaseous medicaments
EP4167920A1 (en) 2020-06-18 2023-04-26 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007333115B2 (en) * 2006-12-12 2013-01-10 Gilead Sciences, Inc. Composition for treating a pulmonary hypertension
WO2009048521A1 (en) * 2007-10-11 2009-04-16 Duke University Potentiating the effect of compound comprising nitric oxide
WO2009099998A2 (en) * 2008-01-31 2009-08-13 Vanderbilt University Therapeutic treatment for lung conditions
CA3130908A1 (en) * 2009-06-30 2010-12-30 Mallinckrodt Hospital Products IP Limited Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
WO2012075420A1 (en) * 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
JP6215314B2 (en) * 2012-05-31 2017-10-18 イノ セラピューティクス エルエルシー Method for administering nitric oxide to arterial blood or arterialized blood
LT2928531T (en) * 2012-12-04 2017-07-10 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US9795756B2 (en) * 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
CN106456666A (en) * 2014-01-10 2017-02-22 Ino治疗有限责任公司 Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
CN106572813B (en) * 2014-03-28 2020-07-17 沙普医疗系统公司 Pattern recognition system for quantifying likelihood of contribution of multiple possible forms of chronic disease to a patient reported dyspnea
BR112018011762A2 (en) * 2015-12-11 2018-12-04 Vero Biotech LLC method and apparatus for administering gases including nitric oxide to control fibrosis
WO2017116776A1 (en) * 2015-12-28 2017-07-06 Geno Llc Method and apparatus for administering nitric oxide with supplemental drugs
EP3970730B1 (en) * 2016-02-12 2024-05-01 Mallinckrodt Pharmaceuticals Ireland Limited System for use and monitoring of inhaled nitric oxide with left ventricular assist devices

Also Published As

Publication number Publication date
IL272314A (en) 2020-03-31
IL272308A (en) 2020-03-31
EP3675840A4 (en) 2021-05-12
JP2020532531A (en) 2020-11-12
CN111372577A (en) 2020-07-03
PH12020500197A1 (en) 2020-10-19
WO2019046415A1 (en) 2019-03-07
US20200188319A1 (en) 2020-06-18
AU2018324004A1 (en) 2020-02-13
EP3675840A1 (en) 2020-07-08
JP2020532521A (en) 2020-11-12
MX2020002194A (en) 2020-11-24
CA3073949A1 (en) 2019-03-07
TW201912151A (en) 2019-04-01
CA3073948A1 (en) 2019-03-07
TW201919590A (en) 2019-06-01
AU2018323547A1 (en) 2020-02-13
BR112020004205A2 (en) 2020-09-01
JP2023100985A (en) 2023-07-19
WO2019046413A1 (en) 2019-03-07
EP3675719A1 (en) 2020-07-08
EP3675719A4 (en) 2021-07-14
US20200360647A1 (en) 2020-11-19
KR20200083443A (en) 2020-07-08
CN111315283A (en) 2020-06-19

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