SG11202000727SA - Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry - Google Patents

Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry

Info

Publication number
SG11202000727SA
SG11202000727SA SG11202000727SA SG11202000727SA SG11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA
Authority
SG
Singapore
Prior art keywords
analysis
systems
methods
real time
mass spectrometry
Prior art date
Application number
SG11202000727SA
Other languages
English (en)
Inventor
Chao-Hsiang Wu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG11202000727SA publication Critical patent/SG11202000727SA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • G01N2001/385Diluting, dispersing or mixing samples diluting by adsorbing a fraction of the sample

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11202000727SA 2017-08-01 2018-08-01 Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry SG11202000727SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762539803P 2017-08-01 2017-08-01
PCT/US2018/044887 WO2019028187A1 (en) 2017-08-01 2018-08-01 SYSTEMS AND METHODS FOR REAL-TIME PREPARATION OF A POLYPEPTIDE SAMPLE FOR MASS SPECTROMETRY ANALYSIS

Publications (1)

Publication Number Publication Date
SG11202000727SA true SG11202000727SA (en) 2020-02-27

Family

ID=63350600

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000727SA SG11202000727SA (en) 2017-08-01 2018-08-01 Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry

Country Status (14)

Country Link
US (1) US20200355582A1 (de)
EP (1) EP3662287B1 (de)
JP (1) JP7237022B2 (de)
KR (1) KR102560646B1 (de)
CN (1) CN110869768B (de)
AU (1) AU2018309027A1 (de)
BR (1) BR112020001885A2 (de)
CA (1) CA3071676A1 (de)
CL (1) CL2020000248A1 (de)
EA (1) EA202090399A1 (de)
IL (1) IL271499A (de)
MA (1) MA49757A (de)
SG (1) SG11202000727SA (de)
WO (1) WO2019028187A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7483731B2 (ja) 2019-02-14 2024-05-15 アムジエン・インコーポレーテツド 試料の調製及びその試料のリアルタイムアッセイの実施のためのシステム及び方法
FR3096459B1 (fr) * 2019-05-20 2024-03-08 Ct Hospitalier Universitaire Montpellier Procédé de préparation d’un échantillon peptidique
CR20230531A (es) * 2021-04-23 2024-01-08 Amgen Inc Composiciones de anticuerpos anti-tslp y usos de las mismas
CN117177992A (zh) * 2021-04-23 2023-12-05 美国安进公司 经修饰的抗tslp抗体
WO2023164672A2 (en) * 2022-02-24 2023-08-31 Venn Biosciences Corporation Sample preparation for glycoproteomic analysis that includes diagnosis of disease

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06511084A (ja) * 1991-09-30 1994-12-08 パーセプティブ バイオシステムズ インコーポレイテッド 蛋白のクロマトグラフィーシステム
CA2146177C (en) * 1995-04-03 2000-09-05 Adrian P. Wade Intelligent flow analysis network
WO1997001755A2 (en) * 1995-06-26 1997-01-16 Perseptive Biosystems, Inc. High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
EP1300679A3 (de) * 1995-06-26 2004-04-14 Perseptive Biosystems, Inc. Molekulare Selektion und Analyse
JPH1194816A (ja) * 1997-09-22 1999-04-09 Mitsubishi Heavy Ind Ltd 高速液体クロマトグラフ分析装置
US20080153711A1 (en) * 2000-02-08 2008-06-26 Regents Of The University Of Michigan Protein microarray system
RS51829B (sr) 2001-08-23 2012-02-29 Genmab A/S. Ljudska antitela specifična za interleukin 15 (il-15)
US20040053356A1 (en) * 2001-12-28 2004-03-18 Mds Proteomics Inc. Enzyme/chemical reactor based protein processing method for proteomics analysis by mass spectrometry
US20040009567A1 (en) * 2001-12-28 2004-01-15 Mds Proteomics Inc. Enzyme/chemical reactor based protein processing method for proteomics analysis by mass spectrometry
WO2003078962A2 (en) * 2002-03-11 2003-09-25 President And Fellows Of Harvard College Detection and quantification of modified proteins
DE602004015932D1 (de) * 2003-01-13 2008-10-02 Univ Michigan Verfahren zur bildung eines protein-mikroarraysystems
TW200508936A (en) * 2003-03-12 2005-03-01 Bionova Corp The establishment of proteome structure profile databases and their uses
WO2005000226A2 (en) * 2003-06-06 2005-01-06 Diversa Corporation Mixed bed multi-dimensional chromatography systems and methods of making and using them
CA2589860A1 (en) 2005-01-24 2006-08-03 Amgen Inc. Humanized anti-amyloid antibody
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
AU2008265128A1 (en) 2007-06-20 2008-12-24 Irm Llc Methods and compositions for treating allergic diseases
JP2010536355A (ja) 2007-08-31 2010-12-02 エフ.ホフマン−ラ ロシュ アーゲー グリコシル化プロファイル分析
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
TWI516501B (zh) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Pcsk9拮抗劑類
CN102687020A (zh) 2009-10-09 2012-09-19 西福根有限公司 利用特征肽和质谱对混合物中的单个重组蛋白进行多重定量
US9453845B2 (en) * 2010-02-01 2016-09-27 Cell Signaling Technology, Inc. Mass spectroscopy analysis of mutant polypeptides in biological samples
EP2548015A1 (de) * 2010-03-15 2013-01-23 Anderson Forschung Group, Inc. Verbesserte massenspektrometrische assays für peptide
US9322014B1 (en) * 2012-11-28 2016-04-26 Sandia Corporation Multiplexed microfluidic approach for nucleic acid enrichment
WO2015072265A1 (ja) * 2013-11-12 2015-05-21 公立大学法人福島県立医科大学 分離分析用キャピラリーデバイス、分離分析用マイクロ流体チップ、タンパク質又はペプチド分析方法、電気泳動装置、及び分離分析用マイクロ流体チップ電気泳動装置
CN106716105B (zh) * 2014-08-19 2020-09-11 基础科学公司 用于质谱分析法的利用注射器输送的超净自动进样器
EP3241022B1 (de) * 2014-12-31 2023-11-08 DH Technologies Development Pte. Ltd. Verfahren zur protein- und peptidreduktion

Also Published As

Publication number Publication date
AU2018309027A1 (en) 2020-01-16
CN110869768A (zh) 2020-03-06
EP3662287B1 (de) 2024-02-28
EP3662287A1 (de) 2020-06-10
CA3071676A1 (en) 2019-02-07
JP7237022B2 (ja) 2023-03-10
CN110869768B (zh) 2023-11-21
CL2020000248A1 (es) 2020-08-14
MA49757A (fr) 2020-06-10
JP2020530103A (ja) 2020-10-15
EA202090399A1 (ru) 2020-05-20
KR20200035093A (ko) 2020-04-01
WO2019028187A1 (en) 2019-02-07
BR112020001885A2 (pt) 2020-08-04
IL271499A (en) 2020-02-27
US20200355582A1 (en) 2020-11-12
KR102560646B1 (ko) 2023-07-27

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