SG11202000727SA - Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry - Google Patents

Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry

Info

Publication number
SG11202000727SA
SG11202000727SA SG11202000727SA SG11202000727SA SG11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA SG 11202000727S A SG11202000727S A SG 11202000727SA
Authority
SG
Singapore
Prior art keywords
analysis
systems
methods
real time
mass spectrometry
Prior art date
Application number
SG11202000727SA
Inventor
Chao-Hsiang Wu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG11202000727SA publication Critical patent/SG11202000727SA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • G01N2001/385Diluting, dispersing or mixing samples diluting by adsorbing a fraction of the sample

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
SG11202000727SA 2017-08-01 2018-08-01 Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry SG11202000727SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762539803P 2017-08-01 2017-08-01
PCT/US2018/044887 WO2019028187A1 (en) 2017-08-01 2018-08-01 Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry

Publications (1)

Publication Number Publication Date
SG11202000727SA true SG11202000727SA (en) 2020-02-27

Family

ID=63350600

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000727SA SG11202000727SA (en) 2017-08-01 2018-08-01 Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry

Country Status (14)

Country Link
US (1) US20200355582A1 (en)
EP (1) EP3662287B1 (en)
JP (1) JP7237022B2 (en)
KR (1) KR102560646B1 (en)
CN (1) CN110869768B (en)
AU (1) AU2018309027A1 (en)
BR (1) BR112020001885A2 (en)
CA (1) CA3071676A1 (en)
CL (1) CL2020000248A1 (en)
EA (1) EA202090399A1 (en)
IL (1) IL271499A (en)
MA (1) MA49757A (en)
SG (1) SG11202000727SA (en)
WO (1) WO2019028187A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3924083B1 (en) * 2019-02-14 2024-05-15 Amgen Inc. Systems and methods for preparing a sample and performing a real-time assay of the sample
FR3096459B1 (en) * 2019-05-20 2024-03-08 Ct Hospitalier Universitaire Montpellier Process for preparing a peptide sample
BR112023022041A2 (en) * 2021-04-23 2023-12-26 Amgen Inc MODIFIED ANTI-TSLP ANTIBODIES
WO2022226339A1 (en) * 2021-04-23 2022-10-27 Amgen Inc. Anti-tslp antibody compositions and uses thereof
WO2023164672A2 (en) * 2022-02-24 2023-08-31 Venn Biosciences Corporation Sample preparation for glycoproteomic analysis that includes diagnosis of disease

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0610297A1 (en) * 1991-09-30 1994-08-17 Perseptive Biosystems, Inc. Protein chromatography system
CA2146177C (en) * 1995-04-03 2000-09-05 Adrian P. Wade Intelligent flow analysis network
EP0835446B1 (en) * 1995-06-26 2003-04-09 Perseptive Biosystems, Inc. High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
EP1300679A3 (en) * 1995-06-26 2004-04-14 Perseptive Biosystems, Inc. Molecular selection and analysis
JPH1194816A (en) * 1997-09-22 1999-04-09 Mitsubishi Heavy Ind Ltd High performance liquid chromatograph analyzer
US20080153711A1 (en) * 2000-02-08 2008-06-26 Regents Of The University Of Michigan Protein microarray system
BR0212136A (en) 2001-08-23 2004-12-07 Genmab As Isolated human monoclonal antibody, methods for inhibiting tnfa production in t cells or monocytes and t cell proliferation, hybridoma, transfectoma, transgenic non-human animal, method for producing a human monoclonal antibody, pharmaceutical composition, methods for treating or preventing a human il-15 mediated disorder, psoriasis and rheumatoid arthritis, method for diagnosing a disease, nucleic acid, and expression vector
US20040053356A1 (en) * 2001-12-28 2004-03-18 Mds Proteomics Inc. Enzyme/chemical reactor based protein processing method for proteomics analysis by mass spectrometry
US20040009567A1 (en) * 2001-12-28 2004-01-15 Mds Proteomics Inc. Enzyme/chemical reactor based protein processing method for proteomics analysis by mass spectrometry
WO2003078962A2 (en) * 2002-03-11 2003-09-25 President And Fellows Of Harvard College Detection and quantification of modified proteins
AU2004204502B2 (en) * 2003-01-13 2008-05-29 The Regents Of The University Of Michigan Method to form a protein microarray system
WO2004081535A2 (en) * 2003-03-12 2004-09-23 Bionova Corporation The establishment of proteome structure profile databases and their uses
WO2005000226A2 (en) * 2003-06-06 2005-01-06 Diversa Corporation Mixed bed multi-dimensional chromatography systems and methods of making and using them
WO2006081171A1 (en) 2005-01-24 2006-08-03 Amgen Inc. Humanized anti-amyloid antibody
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
EA201000006A1 (en) 2007-06-20 2010-10-29 Айрм Ллк METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALLERGIC DISEASES
WO2009027041A1 (en) * 2007-08-31 2009-03-05 F. Hoffmann-La Roche Ag Glycosylation profile analysis
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
TWI516501B (en) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Pcsk9 antagonists
BR112012007815A2 (en) * 2009-10-09 2018-03-20 Symphogen As multiplex quantification of recombinant proteins in a mixture by signature peptides and mass spectrometry.
US9453845B2 (en) * 2010-02-01 2016-09-27 Cell Signaling Technology, Inc. Mass spectroscopy analysis of mutant polypeptides in biological samples
US9274124B2 (en) * 2010-03-15 2016-03-01 Anderson Forschung Group, Inc. Mass spectrometric assays for peptides
US9322014B1 (en) * 2012-11-28 2016-04-26 Sandia Corporation Multiplexed microfluidic approach for nucleic acid enrichment
JP6422131B2 (en) * 2013-11-12 2018-11-14 公立大学法人福島県立医科大学 Capillary device for separation analysis, microfluidic chip for separation analysis, protein or peptide analysis method, electrophoresis apparatus, and microfluidic chip electrophoresis apparatus for separation analysis
CN106716105B (en) * 2014-08-19 2020-09-11 基础科学公司 Ultra-clean autosampler for mass spectrometry using syringe delivery
US10280206B2 (en) * 2014-12-31 2019-05-07 Dh Technologies Development Pte. Ltd. Methods for protein and peptide reduction

Also Published As

Publication number Publication date
CN110869768A (en) 2020-03-06
JP7237022B2 (en) 2023-03-10
US20200355582A1 (en) 2020-11-12
EA202090399A1 (en) 2020-05-20
CA3071676A1 (en) 2019-02-07
WO2019028187A1 (en) 2019-02-07
MA49757A (en) 2020-06-10
KR102560646B1 (en) 2023-07-27
CL2020000248A1 (en) 2020-08-14
KR20200035093A (en) 2020-04-01
BR112020001885A2 (en) 2020-08-04
CN110869768B (en) 2023-11-21
JP2020530103A (en) 2020-10-15
IL271499A (en) 2020-02-27
EP3662287B1 (en) 2024-02-28
AU2018309027A1 (en) 2020-01-16
EP3662287A1 (en) 2020-06-10

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