SG11201907605YA - Light detection systems and methods for using thereof - Google Patents

Light detection systems and methods for using thereof

Info

Publication number
SG11201907605YA
SG11201907605YA SG11201907605YA SG11201907605YA SG11201907605YA SG 11201907605Y A SG11201907605Y A SG 11201907605YA SG 11201907605Y A SG11201907605Y A SG 11201907605YA SG 11201907605Y A SG11201907605Y A SG 11201907605YA SG 11201907605Y A SG11201907605Y A SG 11201907605YA
Authority
SG
Singapore
Prior art keywords
international
california
san jose
methods
light detection
Prior art date
Application number
SG11201907605YA
Other languages
English (en)
Inventor
Jianying Cao
Austin Wu
David Thao Do
Timothy Wayne Petersen
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Publication of SG11201907605YA publication Critical patent/SG11201907605YA/en

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10Beam splitting or combining systems
    • G02B27/1006Beam splitting or combining systems for splitting or combining different wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/30Measuring the intensity of spectral lines directly on the spectrum itself
    • G01J3/36Investigating two or more bands of a spectrum by separate detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J3/50Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors
    • G01J3/51Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors using colour filters
    • G01J3/513Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors using colour filters having fixed filter-detector pairs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106General arrangement of respective parts
    • G01N2021/0112Apparatus in one mechanical, optical or electronic block
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Photometry And Measurement Of Optical Pulse Characteristics (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
SG11201907605YA 2017-02-27 2018-02-12 Light detection systems and methods for using thereof SG11201907605YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762464282P 2017-02-27 2017-02-27
PCT/US2018/017859 WO2018156371A1 (en) 2017-02-27 2018-02-12 Light detection systems and methods for using thereof

Publications (1)

Publication Number Publication Date
SG11201907605YA true SG11201907605YA (en) 2019-09-27

Family

ID=63246686

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201907605YA SG11201907605YA (en) 2017-02-27 2018-02-12 Light detection systems and methods for using thereof

Country Status (9)

Country Link
US (2) US10585031B2 (zh)
EP (1) EP3586104A4 (zh)
JP (1) JP7173978B2 (zh)
KR (1) KR102608673B1 (zh)
CN (1) CN110621978B (zh)
AU (1) AU2018224006B2 (zh)
CA (1) CA3052979A1 (zh)
SG (1) SG11201907605YA (zh)
WO (1) WO2018156371A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3652555B1 (en) * 2017-08-31 2024-03-06 SZ DJI Technology Co., Ltd. A solid state light detection and ranging (lidar) system system and method for improving solid state light detection and ranging (lidar) resolution
JP7348730B2 (ja) 2019-02-22 2023-09-21 シスメックス株式会社 試料測定装置および試料測定方法
CN113508286A (zh) * 2019-03-21 2021-10-15 贝克顿·迪金森公司 光检测系统及其使用方法
US11255771B2 (en) * 2019-06-21 2022-02-22 Captl Llc Photon signal processing for particle detection
CN115176139A (zh) 2020-01-31 2022-10-11 贝克顿·迪金森公司 用于调整训练门以适应流式细胞仪数据的方法和系统
US11821830B2 (en) 2020-02-07 2023-11-21 Becton, Dickinson And Company Clustered wavelength division light detection systems and methods of using the same
WO2021225792A1 (en) 2020-05-06 2021-11-11 Becton, Dickinson And Company Methods and systems for characterizing spillover spreading in flow cytometer data
US11754487B2 (en) 2020-06-24 2023-09-12 Becton, Dickinson And Company Flow cytometric droplet dispensing systems and methods for using the same
US11680889B2 (en) 2020-06-26 2023-06-20 Becton, Dickinson And Company Dual excitation beams for irradiating a sample in a flow stream and methods for using same
CN112229781A (zh) * 2020-09-07 2021-01-15 桂林电子科技大学 一种改进的流式细胞仪的光谱细分式光纤集散探测装置
CN112147044A (zh) * 2020-09-07 2020-12-29 桂林电子科技大学 用于流式细胞仪的光谱细分式光纤集散探测装置
CN117642619A (zh) * 2021-05-14 2024-03-01 贝克顿·迪金森公司 采用光谱鉴别法检测光的系统及其使用方法
US20230053122A1 (en) 2021-08-10 2023-02-16 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
US20230046207A1 (en) 2021-08-10 2023-02-16 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960449A (en) 1975-06-05 1976-06-01 The Board Of Trustees Of Leland Stanford Junior University Measurement of angular dependence of scattered light in a flowing stream
US4347935A (en) 1979-05-16 1982-09-07 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for electrostatically sorting biological cells
US4667830A (en) 1981-06-15 1987-05-26 The Board Of Trustees Of The Leland Stanford Junior University Method and means for sorting individual particles into containers for culturing, cloning, analysis, or the like
US4690561A (en) * 1985-01-18 1987-09-01 Canon Kabushiki Kaisha Particle analyzing apparatus
US4770992A (en) 1985-11-27 1988-09-13 Den Engh Gerrit J Van Detection of specific DNA sequences by flow cytometry
US4704891A (en) 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
US5245318A (en) 1987-07-24 1993-09-14 Canon Kabushiki Kaisha Particle analyzing apparatus having pressure control system
US5040890A (en) 1987-11-25 1991-08-20 Becton, Dickinson And Company Sheathed particle flow controlled by differential pressure
US5047321A (en) 1988-06-15 1991-09-10 Becton Dickinson & Co. Method for analysis of cellular components of a fluid
US5408307A (en) * 1988-07-11 1995-04-18 Omron Tateisi Electronics Co. Cell analyzer
US5030002A (en) 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube
EP0515211A3 (en) 1991-05-23 1993-04-07 Becton Dickinson And Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
DE69218912T2 (de) 1991-08-28 1997-10-09 Becton Dickinson Co Schwerkraftsattraktionsmaschine zur anpassungsfähigen autoclusterbildung n-dimensionaler datenströme
JPH05130995A (ja) * 1991-11-14 1993-05-28 Olympus Optical Co Ltd 空間差分を用いた光断層イメージング装置
US5422712A (en) * 1992-04-01 1995-06-06 Toa Medical Electronics Co., Ltd. Apparatus for measuring fluorescent spectra of particles in a flow
NO930980L (no) * 1993-03-18 1994-09-19 Flowtech As Optisk konfigurasjon for væskeströmcytofotometer
US5483469A (en) 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US5464581A (en) 1993-08-02 1995-11-07 The Regents Of The University Of California Flow cytometer
US5700692A (en) 1994-09-27 1997-12-23 Becton Dickinson And Company Flow sorter with video-regulated droplet spacing
US5643796A (en) 1994-10-14 1997-07-01 University Of Washington System for sensing droplet formation time delay in a flow cytometer
US5602039A (en) 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
US5620842A (en) 1995-03-29 1997-04-15 Becton Dickinson And Company Determination of the number of fluorescent molecules on calibration beads for flow cytometry
US6307629B1 (en) 1997-08-12 2001-10-23 Lj Laboratories, L.L.C. Apparatus and method for measuring optical characteristics of an object
US5995235A (en) * 1997-02-13 1999-11-30 Applied Materials, Inc. Bandpass photon detector
US6821740B2 (en) 1998-02-25 2004-11-23 Becton, Dickinson And Company Flow cytometric methods for the concurrent detection of discrete functional conformations of PRB in single cells
US6249348B1 (en) 1998-11-23 2001-06-19 Lj Laboratories, L.L.C. Integrated spectrometer assembly and methods
US6198864B1 (en) 1998-11-24 2001-03-06 Agilent Technologies, Inc. Optical wavelength demultiplexer
US6608682B2 (en) * 1999-01-25 2003-08-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6372506B1 (en) 1999-07-02 2002-04-16 Becton, Dickinson And Company Apparatus and method for verifying drop delay in a flow cytometer
US6687395B1 (en) 1999-07-21 2004-02-03 Surromed, Inc. System for microvolume laser scanning cytometry
US6813017B1 (en) 1999-10-20 2004-11-02 Becton, Dickinson And Company Apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
US6461058B1 (en) 1999-10-28 2002-10-08 Agilent Technologies, Inc. Optoelectronic component
US6362888B1 (en) 1999-12-23 2002-03-26 Lj Laboratories, L.L.C. Spectrometer assembly
US6809804B1 (en) 2000-05-11 2004-10-26 Becton, Dickinson And Company System and method for providing improved event reading and data processing capabilities in a flow cytometer
WO2002101339A2 (en) 2000-10-12 2002-12-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6594009B2 (en) 2001-02-27 2003-07-15 Honeywell International Inc. Flow cytometer and ultraviolet light disinfecting systems
US6870976B2 (en) 2001-03-13 2005-03-22 Opnext, Inc. Filter based multiplexer/demultiplexer component
US7345758B2 (en) 2001-05-17 2008-03-18 Cytopeia Apparatus for analyzing and sorting biological particles
WO2003016842A1 (fr) 2001-08-13 2003-02-27 Hamamatsu Photonics K.K. Spectrometre et procede de separation spectrale
US6683314B2 (en) 2001-08-28 2004-01-27 Becton, Dickinson And Company Fluorescence detection instrument with reflective transfer legs for color decimation
US6870165B2 (en) 2001-10-19 2005-03-22 Biocal Technology, Inc. Multi-color multiplexed analysis in a bio-separation system
US7201875B2 (en) 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
US7304723B2 (en) 2002-10-25 2007-12-04 Arkray, Inc. Light source unit, photoreceptive unit and multichannel photodetector using the same
WO2004076997A1 (ja) 2003-02-28 2004-09-10 Hamamatsu Photonics K.K. 分光装置
JP4109174B2 (ja) * 2003-09-17 2008-07-02 浜松ホトニクス株式会社 分光装置
US6961126B2 (en) * 2003-10-23 2005-11-01 Honeywell International Inc. Optical wavelength splitter
US7098439B2 (en) * 2003-12-22 2006-08-29 Searete Llc Augmented photo-detector filter
US7792228B2 (en) 2004-03-15 2010-09-07 Samsung Electronics Co., Ltd. Apparatus and method for digital down-conversion in a multi-mode wireless terminal
US7264794B2 (en) 2004-12-17 2007-09-04 The General Hospital Methods of in vivo cytometry
JP4756948B2 (ja) 2005-08-08 2011-08-24 ベイバイオサイエンス株式会社 フローサイトメータおよびフローサイトメトリ方法
US7595473B2 (en) * 2005-08-22 2009-09-29 Tufts University Method and system of array imaging
DE102005054184B4 (de) 2005-11-14 2020-10-29 Carl Zeiss Microscopy Gmbh Multispektrale Beleuchtungsvorrichtung und Messverfahren
US8149402B2 (en) * 2006-02-22 2012-04-03 Accuri Cytometers, Inc. Optical system for a flow cytometer
EP1987389B1 (en) 2006-02-22 2017-06-14 Accuri Instruments Inc. Optical system for a flow cytometer
US7738094B2 (en) 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
US7728974B2 (en) 2007-02-07 2010-06-01 Cytopeia, Inc. Enhanced detection system and method
WO2009005748A1 (en) * 2007-06-29 2009-01-08 The Trustees Of Columbia University In The City Ofnew York Optical imaging or spectroscopy systems and methods
US8140300B2 (en) 2008-05-15 2012-03-20 Becton, Dickinson And Company High throughput flow cytometer operation with data quality assessment and control
US8233146B2 (en) 2009-01-13 2012-07-31 Becton, Dickinson And Company Cuvette for flow-type particle analyzer
JP5382852B2 (ja) 2009-02-06 2014-01-08 株式会社オンチップ・バイオテクノロジーズ 使い捨てチップ型フローセルとそれを用いたフローサイトメーター
EP2400892B1 (en) * 2009-02-27 2020-03-25 Beckman Coulter, Inc. Fluorescence detection instrument with orthogonal laser entry
US8487235B2 (en) 2009-04-13 2013-07-16 Rockwell Automation Technologies, Inc. Photoelectric sensor for sensing a target at a predetermined location
US8223445B2 (en) 2009-09-21 2012-07-17 Cytopeia Lens positioning apparatus
CN103154784B (zh) * 2010-07-01 2016-11-16 新港公司 光多路分用系统
US8488244B1 (en) * 2010-07-12 2013-07-16 Alliance Fiber Optic Products, Inc. Ultra compact optical multiplexer or demultiplexer
US8528427B2 (en) 2010-10-29 2013-09-10 Becton, Dickinson And Company Dual feedback vacuum fluidics for a flow-type particle analyzer
JP5681517B2 (ja) 2011-02-15 2015-03-11 新日本空調株式会社 粒子導電性判別装置及び粒子導電性判別方法
CN103649294B (zh) 2011-04-29 2016-05-18 贝克顿·迪金森公司 多路分类系统和方法
US9037204B2 (en) * 2011-09-07 2015-05-19 Covidien Lp Filtered detector array for optical patient sensors
CN103906496B (zh) 2011-09-30 2018-03-06 贝克顿·迪金森公司 流体交换方法与装置
US8599487B2 (en) 2011-11-21 2013-12-03 Coherent, Inc. Beam-combiner for fiber-delivered laser-beams of different wavelengths
US9518925B2 (en) * 2011-12-22 2016-12-13 Radisens Diagnostics Limited High resolution, wide dynamic range microfluidic detection system
CN104508455B (zh) 2012-08-07 2017-10-03 索尼公司 用于细颗粒测量设备的层流监控方法、细颗粒分析方法以及细颗粒测量设备
US8994941B2 (en) 2012-11-28 2015-03-31 General Electric Company Optical system, apparatus and method for performing flow cytometry
WO2014139128A1 (en) 2013-03-14 2014-09-18 Source Photonics (Chengdu) Co., Ltd. Actively aligned detectors for optical and optoelectronic arrays
WO2014144868A1 (en) * 2013-03-15 2014-09-18 Beckman Coulter, Inc. Compound optical flow cells and method of manufacture and use
US9366616B2 (en) 2013-04-12 2016-06-14 Becton, Dickinson And Company Automated set-up for cell sorting
US9957554B1 (en) * 2013-12-19 2018-05-01 National Technology & Engineering Solutions Of Sandia, Llc Microfluidic platform for multiplexed detection in single cells and methods thereof
CN107850542B (zh) * 2015-08-21 2023-10-24 株式会社日立制作所 光检测装置
US10613096B2 (en) * 2015-08-28 2020-04-07 Captl Llc Multi-spectral microparticle-fluorescence photon cytometry
CN205241687U (zh) 2015-09-28 2016-05-18 周辉 激光活体肿瘤细胞或其它病理细胞检测装置
US10187175B2 (en) * 2016-11-18 2019-01-22 Kohoku Kogyo Co., Ltd. Optical multiplexer/demultiplexer and optical transceiver

Also Published As

Publication number Publication date
EP3586104A4 (en) 2020-12-16
US20180246029A1 (en) 2018-08-30
JP7173978B2 (ja) 2022-11-17
WO2018156371A1 (en) 2018-08-30
CN110621978B (zh) 2023-07-11
CN110621978A (zh) 2019-12-27
US11085869B2 (en) 2021-08-10
AU2018224006B2 (en) 2022-09-22
US10585031B2 (en) 2020-03-10
US20200158623A1 (en) 2020-05-21
JP2020512540A (ja) 2020-04-23
AU2018224006A1 (en) 2019-08-15
CA3052979A1 (en) 2018-08-30
EP3586104A1 (en) 2020-01-01
KR102608673B1 (ko) 2023-11-30
KR20190115095A (ko) 2019-10-10

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