SG11201903841PA - High speed deep tissue imaging system using multiplexed scanned temporal focusing - Google Patents

High speed deep tissue imaging system using multiplexed scanned temporal focusing

Info

Publication number
SG11201903841PA
SG11201903841PA SG11201903841PA SG11201903841PA SG11201903841PA SG 11201903841P A SG11201903841P A SG 11201903841PA SG 11201903841P A SG11201903841P A SG 11201903841PA SG 11201903841P A SG11201903841P A SG 11201903841PA SG 11201903841P A SG11201903841P A SG 11201903841PA
Authority
SG
Singapore
Prior art keywords
sub
international
target volume
multiplexed
laser pulse
Prior art date
Application number
SG11201903841PA
Other languages
English (en)
Inventor
Alipasha Vaziri
Original Assignee
Univ Vienna
Alipasha Vaziri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vienna, Alipasha Vaziri filed Critical Univ Vienna
Publication of SG11201903841PA publication Critical patent/SG11201903841PA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/10—Scanning
    • G01N2201/105—Purely optical scan
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/005—Optical devices external to the laser cavity, specially adapted for lasers, e.g. for homogenisation of the beam or for manipulating laser pulses, e.g. pulse shaping

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Electromagnetism (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Ink Jet (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
SG11201903841PA 2016-10-30 2017-10-30 High speed deep tissue imaging system using multiplexed scanned temporal focusing SG11201903841PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662414788P 2016-10-30 2016-10-30
PCT/US2017/059044 WO2018081711A1 (en) 2016-10-30 2017-10-30 High speed deep tissue imaging system using multiplexed scanned temporal focusing

Publications (1)

Publication Number Publication Date
SG11201903841PA true SG11201903841PA (en) 2019-05-30

Family

ID=62025515

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903841PA SG11201903841PA (en) 2016-10-30 2017-10-30 High speed deep tissue imaging system using multiplexed scanned temporal focusing

Country Status (9)

Country Link
US (1) US11988603B2 (ja)
EP (1) EP3532827B1 (ja)
JP (1) JP2019536059A (ja)
KR (1) KR20190082252A (ja)
CN (1) CN110168351A (ja)
CA (1) CA3042229A1 (ja)
IL (1) IL266284B2 (ja)
SG (1) SG11201903841PA (ja)
WO (1) WO2018081711A1 (ja)

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US20220034805A1 (en) * 2018-09-20 2022-02-03 University Court Of The University Of St Andrews Imaging an object through a scattering medium
CN109745010B (zh) * 2019-01-31 2024-05-14 北京超维景生物科技有限公司 定位式吸附显微镜探测装置及激光扫描显微镜
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US11408032B2 (en) 2020-01-17 2022-08-09 Element Biosciences, Inc. Tube lens design for improved depth-of-field
GB2593456B (en) * 2020-03-18 2024-02-28 Thermo Fisher Scient Ecublens Sarl Double-pulse laser system
WO2022061191A1 (en) * 2020-09-20 2022-03-24 The Regents Of The University Of California Transverse sheet illumination microscopy (transim)
CN112816447B (zh) * 2020-12-30 2022-02-15 华南理工大学 基于二维频率空间编码的多光子激发成像系统及成像方法
US11789333B2 (en) 2021-03-01 2023-10-17 Lawrence Livermore National Security, Llc System and method for temporal dispersion compensator
TWI764627B (zh) * 2021-03-17 2022-05-11 上儀股份有限公司 一種雷射脈寬高調製系統
EP4334707A1 (en) * 2021-05-05 2024-03-13 The Rockefeller University Spatiotemporal multiplexing module
CN113484281B (zh) * 2021-05-28 2023-03-14 太原理工大学 一种基于生物组织独特光散射特性的光学加密装置及方法
CN116148227B (zh) * 2023-04-23 2023-07-28 广东大湾区空天信息研究院 时间分辨光谱快速测量系统及方法

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Also Published As

Publication number Publication date
EP3532827B1 (en) 2023-05-31
JP2019536059A (ja) 2019-12-12
IL266284B1 (en) 2023-09-01
CA3042229A1 (en) 2018-05-03
IL266284B2 (en) 2024-01-01
US11988603B2 (en) 2024-05-21
US20200182792A1 (en) 2020-06-11
IL266284A (en) 2019-06-30
WO2018081711A1 (en) 2018-05-03
EP3532827A1 (en) 2019-09-04
EP3532827A4 (en) 2020-07-01
KR20190082252A (ko) 2019-07-09
CN110168351A (zh) 2019-08-23

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